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Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly in regions with high hepatitis B virus prevalence.

24 Jan 2026

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer (CRPC).

24 Jan 2026

Blood-based epigenetic signatures enable early risk assessment in prediabetes

Prediabetes is an extremely heterogeneous metabolic disorder. Scientists from several partner institutes of the German Center for Diabetes Research (DZD) have now used artificial intelligence (AI) to identify epigenetic markers that indicate an elevated risk of complications.

24 Jan 2026

Nearly half of adults now live with heart disease as obesity and diabetes surge

The 2026 American Heart Association Heart Disease and Stroke Statistics report shows that nearly half of adults are living with cardiovascular disease, with cardiometabolic risk factors projected to rise substantially by 2050. Despite progress in smoking reduction and cholesterol control, worsening obesity, diabetes, hypertension, sleep health, and persistent inequities threaten future cardiovascular health.

22 Jan 2026

Discovery explains why people with IBD have higher risk of colorectal cancer

A chain of immune reactions in the gut—driven by a key signaling protein and a surge of white blood cells from the bone marrow—may help explain why people with inflammatory bowel disease (IBD) have a higher risk of colorectal cancer, according to a preclinical study by Weill Cornell Medicine investigators.

22 Jan 2026

Methionine: A dietary key to surviving infection

As soon as you are wounded-whether from grabbing a hot pan or contracting the flu-you begin a unique journey through variable symptoms toward either recovery or death.

22 Jan 2026

Lifelong health: The Northern Finland Birth Cohort 1966 enters a new era of aging research

One of the world’s most extensive birth cohorts is now entering later adulthood. At the University of Oulu in Finland, the Northern Finland Birth Cohort 1966 (NFBC1966) is launching a major new follow-up combining decades of biological, social, and environmental data with modern digital health tools to examine how lifelong exposures and the genome shape health and aging.

22 Jan 2026

A routine blood test may reveal who is most at risk of osteoporosis

A routine creatinine blood test may identify individuals at higher risk for osteoporosis and fractures, highlighting its potential as a risk assessment tool.

22 Jan 2026

High-dose inhaled nitric oxide could fight multidrug-resistant infections

Overuse of antibiotics has accelerated the development of bacterial resistance to conventional drugs, a global health crisis projected to result in more than 10 million deaths annually by 2050.

21 Jan 2026

Study shows DHPS enzyme controls macrophage maturation across multiple organs

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

21 Jan 2026

Pandemic linked to lasting drops in diagnosis rates for major conditions

There has been a lasting and disproportionate impact of the Covid-19 pandemic on diagnosis rates for conditions including depression, asthma and osteoporosis.

21 Jan 2026

Nutrition experts call for dietary fiber recognition as an essential nutrient

Ōtākou Whakaihu Waka nutrition experts are calling for dietary fiber to be officially recognized internationally as an essential nutrient - the first 'new' essential nutrient in more than 50 years.

21 Jan 2026

Tracing the decline in American heart disease mortality

Following a five-year upward trend likely impacted by the COVID pandemic, the number of heart disease and stroke deaths has declined, yet, heart disease and stroke still kill more people in the U.S. each year than any other cause, according to data reported in the 2026 Heart Disease and Stroke Statistics: A Report of U.S. and Global Data From the American Heart Association.

21 Jan 2026

Scientists discover why patients with chronic kidney disease die of heart problems

Scientists have discovered an answer to the longstanding mystery of why more than half of patients with chronic kidney disease ultimately die of cardiovascular problems: Their kidneys produce a substance that poisons the heart.

20 Jan 2026

How "old RNA" reshapes sperm metabolism

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown.

20 Jan 2026

Blood metabolites reveal who will develop type 2 diabetes years before diagnosis

This large prospective study integrated blood metabolomics, genetics, and lifestyle data to identify hundreds of metabolites associated with long-term risk of type 2 diabetes in initially healthy adults. A validated 44-metabolite signature improved risk prediction beyond conventional factors, offering insights into biological pathways and opportunities for earlier, more precise prevention.

18 Jan 2026

Majority of older adults in Ireland have poorly controlled high blood pressure

High blood pressure becomes more common after age 40years yet new research from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin shows that many people in Ireland with hypertension are still not optimally diagnosed or treated based on European Gudelines.

16 Jan 2026

Kidney News and Research

Diagnostic prognostic and therapeutic relevance of PIVKA-II in hepatocellular carcinoma

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Blood-based epigenetic signatures enable early risk assessment in prediabetes

Nearly half of adults now live with heart disease as obesity and diabetes surge

Discovery explains why people with IBD have higher risk of colorectal cancer

Methionine: A dietary key to surviving infection

Lifelong health: The Northern Finland Birth Cohort 1966 enters a new era of aging research

A routine blood test may reveal who is most at risk of osteoporosis

High-dose inhaled nitric oxide could fight multidrug-resistant infections

Study shows DHPS enzyme controls macrophage maturation across multiple organs

Pandemic linked to lasting drops in diagnosis rates for major conditions

Nutrition experts call for dietary fiber recognition as an essential nutrient

Tracing the decline in American heart disease mortality

Scientists discover why patients with chronic kidney disease die of heart problems

How "old RNA" reshapes sperm metabolism

Blood metabolites reveal who will develop type 2 diabetes years before diagnosis

Majority of older adults in Ireland have poorly controlled high blood pressure

PSA-based tool improves decision making for prostate cancer screening and treatment

Web-based tool could aid in early detection and prevention of chronic kidney disease

Cancer mortality drops 34% as treatments and early detection improve

Event guide: 8th CKD Summit 2026 eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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