Neutrophils News and Research

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Long-term antibiotic use in preemies promotes drug-resistant gut bacteria

Very preterm infants are often sick and require antibiotic treatment to save their lives. However, when this form of therapy lasts for 20 months or more, it may affect the gut microbiome over the long-term in addition to its acute effects.

10 Sep 2019

Fat-filled immune cells found in victims of vaping illness

The frightening outbreak of mysterious respiratory illness linked to the use of e-cigarettes, or vaping, have shaken the medical community.

9 Sep 2019

Researchers find diverse immune cell profiles, roles in breast cancer resistance to immunotherapy

In recent years it has been increasingly appreciated that immune cells within the tumor microenvironment contribute to tumor progression and, importantly, to the tumor's response to therapy.

27 Aug 2019

Vaping promotes the same cellular responses found in smokers with emphysema

E-cigarette "vaping" is widely assumed to be safer than cigarette smoking, but scientists at the University of North Carolina School of Medicine have uncovered evidence suggesting that vaping promotes the same cellular responses found in smokers who suffer with emphysema.

22 Aug 2019

Gallstone formation may be driven by neutrophils

Neutrophils generate sticky webs of DNA called neutrophil extracellular traps (NETs) that act as a “glue” during gallstone formation.

19 Aug 2019

Mortality risk from yellow fever can be identified sooner

Approximately ten out of every 100 people who are bitten by mosquitos infected by the yellow fever virus develop symptoms of the disease. Although most infected people do not develop the disease, it is lethal to approximately 40% of those who do.

14 Aug 2019

Better insights into human defense mechanisms on the molecular level

With the help of new technology, the researchers of the University of Turku in Finland have gained more detailed information on the diversity of the human lymphatic system than before.

13 Aug 2019

New technology uses immune system to deliver drugs directly to infection sites

A researcher at Washington State University Health Sciences Spokane has developed a new technology that harnesses the immune system to deliver drugs directly to infection sites within the body.

9 Aug 2019

Moffitt study uncovers subtypes of squamous cell lung cancer

Lung cancer is the number one cause of cancer-related deaths in the United States, with squamous cell lung cancer (SCC) being one of the common types.

8 Aug 2019

Stimulating immune cells with nanosecond pulsed electric fields can cause them to respond

Nanosecond pulsed electric fields produce strong electrical effects by focusing a high powered electrical pulse over a very short period of time.

7 Aug 2019

Receptor in the uterus can detect sperm molecule, aids in sperm survival

Why does it take 200 million sperms to fertilize a single egg? The single sperm that reached the finished line has successfully survived multiple checkpoints within the female reproductive tract, dubbed as pre-fertilization events. Now, a new study shows that the uterus contains receptors that facilitate sperm survival.

19 Jul 2019

Study: Megakaryocytes play an important role in cell migration

Hematopoiesis is the process of forming blood cells, which occurs predominantly in the bone marrow. The bone marrow produces all types of blood cells: red blood cells, platelets, and white blood cells.

18 Jul 2019

Artificial intelligence can help accurately predict acute kidney injury in burn patients

Many burn victims suffer acute kidney injury (AKI), but early recognition of AKI remains challenging. Now an Artificial Intelligence / Machine Learning (AI/ML) model developed at UC Davis Health and reported in a new study can predict acute kidney injury quicker and more accurately than ever.

12 Jul 2019

How cell-free DNA can be targeted to prevent spread of tumors

Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes.

12 Jul 2019

An injection of nanoparticles for spinal cord injuries

Researchers from the University of Michigan used nanopaticles injection to prevent the immune cells of the body from impairing the healing of injured brain and spinal cord. They call this an “EpiPen” or emergency rescue drug for the brain and spinal cord when they suffer trauma.

11 Jul 2019

Scientists identify mechanism that makes babies more likely than adults to die from sepsis

An immune mechanism that makes babies more likely than adults to die from sepsis has been identified by scientists affiliated with the Center for Research on Inflammatory Diseases in Ribeirão Preto, São Paulo State (Brazil).

4 Jul 2019

$FDA grants accelerated approval to new treatment for refractory multiple myeloma$

FDA grants accelerated approval to new treatment for refractory multiple myeloma

Today, the U.S. Food and Drug Administration granted accelerated approval to Xpovio (selinexor) tablets in combination with the corticosteroid dexamethasone for the treatment of adult patients with relapsed refractory multiple myeloma who have received at least four prior therapies and whose disease is resistant to several other forms of treatment, including at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody.

3 Jul 2019

Comprehensive gene activity database could significantly reduce animal use

A comprehensive database of gene activity in mice across ten disease models, which could significantly reduce animal use worldwide, has been developed by scientists at the Francis Crick Institute, which gives a full picture of the immune response to different pathogens.

29 Jun 2019

Researchers find a way to divide patients with ulcerative colitis into groups

Researchers at Karolinska Institutet in Sweden have found a way of using gene expression conserved across species to divide patients with the inflammatory bowel disease ulcerative colitis into two distinct groups.

29 Jun 2019

Study shows how SIRT1 plays key role in maintaining the regenerative potential of leukemic stem cells

Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the remission and persist as a major barrier to cure.

11 Jun 2019