Prophylaxis News and Research

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Study finds fewer new cases of HCV in HIV-negative men who have sex with PrEP-using men

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found fewer new cases of hepatitis C infection (commonly called HCV), despite very high rates of other sexually-transmitted infections, in HIV-negative men who have sex with men who take pre-exposure prophylaxis (PrEP) treatments.

10 Nov 2019

Repeated infusions of ketamine for migraines or pain not linked to increased adverse events

Repeated infusions of ketamine treatments for migraines or pain was not associated with increased risk for hepatotoxicity or psychomimetic adverse drug events (ADEs), according to research from Thomas Jefferson University Hospital in Philadelphia, PA, and the University of Virginia at Charlottesville.

6 Nov 2019

Addressing perceived stigma about taking HIV medication can help women at risk

Stigma is an important contributor to the continued HIV epidemic in the United States. While pre-exposure prophylaxis (PrEP) is a medication that can be taken to prevent HIV infection, previous research has shown that a barrier preventing gay, bisexual and other men who have sex with men from using PrEP is fear that partners, family members or community members would believe that those who use PrEP are HIV infected.

4 Nov 2019

Optimal implementation of existing, new interventions essential to end HIV pandemic

Optimal implementation of existing HIV prevention and treatment tools and continued development of new interventions are essential to ending the HIV pandemic, National Institutes of Health experts write in a commentary Clinical Infectious Diseases.

24 Oct 2019

Proactive administration of amiodarone to patients after common heart surgery improves outcomes

Proactive administration of amiodarone to patients recovering from a common heart surgery shows promise in preventing postoperative atrial fibrillation, a serious and expensive complication with potential long-term consequences.

24 Oct 2019

CRISPR helps find difficult to detect cancer cells

Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in the cancer cells that can make the cells invisible to the immune system normally. Some of the cancers cells can now develop other ways to disguise themselves from being killed by the immune system.

15 Oct 2019

New findings highlight the 'PrEP gap' for men who have sex with men in the EU

This estimate on the "PrEP gap" in Europe was published in a paper in Eurosurveillance today stating that 500 000 men who have sex with men in the European Union currently cannot access HIV pre-exposure prophylaxis (PrEP), despite being very likely to use it.

11 Oct 2019

New $4.5 million federal grant to make more HIV testing available in the Chicago area

More HIV testing will be available in the Chicago area, thanks to a five-year, $4.5 million federal public health grant recently awarded to the University of Chicago Medicine.

3 Oct 2019

Findings highlight critical importance of mass dog vaccination

The World Health Organization has made it a goal to eliminate human rabies deaths due to dog bites by the year 2030. An increase in dog rabies vaccination rates decreases dog rabies cases, human exposure, and human deaths, researchers now report in PLOS Neglected Tropical Diseases.

From PLOS ONE 25 Sep 2019

New drug delivery system could be a boon for those on a multi-drug regimen

Researchers from the University of North Carolina at Chapel Hill have developed a unique new multi-drug delivery system that could p-rove to be useful for persons who need to take several drugs in a day as part of a regimen.

23 Sep 2019

Drug-sparing HIV regimens have become new standards of care, says GlobalData

Reductions in pill burden and dosing, improvements in safety and tolerability, and increased barriers to resistance have changed HIV management.

17 Sep 2019

NIAID experts call for innovative research on STIs

Sexually transmitted infections, or STIs, pose a significant public health challenge. Globally, more than one million new STI cases are diagnosed each day.

10 Sep 2019

HIV diagnoses fall to lowest level since 2000

The number of new HIV diagnoses in the UK has fallen to a record low since 2000, according to a new report by Public Health England.

4 Sep 2019

Needle stick injuries are common and can transmit many blood-borne pathogens

Needle stick injuries (NSIs) can transmit more than 20 blood-borne pathogens, including HIV, hepatitis B virus (HBV), hepatitis C virus (HCV) and, more rarely, malaria, human T cell leukemia virus and Ebola.

25 Aug 2019

New protocol for HIV prevention drug reduces the number of pills required

Health officials and AIDS advocates in San Francisco hope to expand the use of an effective HIV prevention drug with a new approach that requires fewer pills than the standard once-a-day regimen.

29 Jul 2019

Vaginal ring used by most women for HIV prevention in open-label study

In an open-label study of women in southern and eastern Africa, a vaginal ring that is inserted once a month and slowly releases an antiviral drug was estimated to reduce the risk of HIV by 39%, according to statistical modeling.

24 Jul 2019

Tailored adherence strategies needed to engage young African women in consistent PrEP use

In a study of open-label Truvada as daily pre-exposure prophylaxis (PrEP) to prevent HIV among 427 young African women and adolescent girls, 95% initiated the HIV prevention strategy, and most used PrEP for the first three months.

24 Jul 2019

Continuation of community-wide HIV testing could lead to reductions in new HIV cases

Continuation of community-wide HIV testing and prompt initiation of treatment as delivered in the HPTN 071 study in South Africa and Zambia could lead to substantial reductions in new HIV cases, be cost-effective, and help to achieve the UNAIDS 2030 targets, according to projections from mathematical modeling and cost-effectiveness analyses presented today at the 10th International AIDS Society Conference on HIV Science in Mexico City.

23 Jul 2019

Study finds new way to help cancer doctors predict blood clots in patients with multiple myeloma

New research from the Hutchinson Institute for Cancer Outcomes Research- which is based at Fred Hutchinson Cancer Research Center- along with the University of Washington and the Seattle Cancer Care Alliance, identifies a simple way to help cancer doctors caring for patients with multiple myeloma to predict blood clots in order to take preventive action.

19 Jul 2019

Even when HIV prevention drug is covered, other costs block treatment

Three years ago, Corey Walsh, who was in a relationship with a man who was HIV-positive, got a prescription for Truvada, a drug approved by the Food and Drug Administration to prevent infection with the virus that causes AIDS.

15 Jul 2019