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UC San Diego researchers win DARPA award to develop improved red blood cells

Researchers at the University of California San Diego School of Medicine have been awarded a contract of up to $11.312 million from the Defense Advanced Research Projects Agency (DARPA) to pursue a high-risk, high-reward research project aimed at developing optimized red blood cells that can temporarily boost human performance and health.

31 Aug 2026

New BioTAK score accurately identifies Takotsubo syndrome before catheterization

Takotsubo syndrome is an acute heart condition that primarily affects postmenopausal women and is often triggered by severe emotional or physical stress.

31 Aug 2026

New tool predicts heart failure treatment effects on blood pressure, kidney function and serum potassium

A new heart failure (HF) treatment effect calculator could help overcome one of the largest barriers to effective heart failure care by predicting the expected effects of treatment on blood pressure, kidney function and potassium levels.

31 Aug 2026

Night owls face tougher work-life balance and higher mental risks

Balancing work and personal life is more challenging for evening types, or "night owls", than for morning types, or "early birds".

31 Aug 2026

Newly discovered lung immune cells could transform future flu vaccine design

Influenza continues to cause major illness each year in the United States, leading to more than 35,000 deaths annually. Children, older adults, pregnant individuals, people with weakened immune systems, and those with chronic conditions such as heart disease, metabolic disorders, and cancer are especially vulnerable.

31 Aug 2026

Early cardiac monitoring reveals hidden arrhythmias in patients with unexplained fainting

Early ECG monitoring initiated in the emergency department (ED) has the potential to transform the care of thousands of patients who attend the ED with unexplained fainting.

31 Aug 2026

Anticoagulation lowers subclinical leaflet thrombosis after TAVI procedure

After transcatheter aortic valve implantation (TAVI), anticoagulation reduced imaging signs of clot formation on the new valve compared with antiplatelet therapy, without compromising safety. This was the main finding of the ACASA-TAVI trial presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in JAMA.

31 Aug 2026

Protein build-up may shape cancer drug response

The way cancer-causing proteins accumulate in tumors may influence how effectively a promising new generation of medicines can remove them, a study suggests.

31 Aug 2026

A personalized elimination diet changed the gut microbiome in people with migraine

In a 12-week randomized, sham-controlled trial of 98 adults with migraine, eliminating IgG-positive foods altered gut microbial composition and produced a greater reduction in serum zonulin than a sham elimination diet. The microbial changes were associated with previously reported reductions in CGRP and IL-6 and improvements in migraine and sleep, although the authors emphasized that these mechanistic links remain exploratory.

31 Aug 2026

The scale told a similar story across three diets. The liver told a different one

In a randomized controlled trial of people with metabolically unhealthy obesity, approximately 10% weight loss improved insulin sensitivity and several cardiometabolic measures across ketogenic, Mediterranean, and very-low-fat plant-forward diets. However, the very-low-carbohydrate ketogenic diet produced larger improvements in hepatic insulin sensitivity and greater reductions in liver fat and several glucose and insulin measures than the higher-carbohydrate diets.

31 Aug 2026

Is there a best day to take GLP-1 drugs? Researchers looked for an answer

A systematic review of 1,000 screened records identified only three eligible studies examining administration timing for semaglutide, and none directly compared different days of the week or assessed tirzepatide timing. The limited evidence suggests flexible dosing may support adherence and tolerability without compromising glycemic control or weight loss, but these findings rely largely on indirect evidence and expert opinion rather than direct comparative trials.

30 Aug 2026

Does a psychedelic need an awake brain to have lasting effects? This mouse study offers a clue

A single dose of psilocybin produced a lasting increase in sociability for at least two weeks in Cntnap2-knockout mice with social deficits, while it did not enhance sociability overall in mice with normal social behavior. The effect required 5-HT2A receptor activation and persisted when psilocybin was administered under light anesthesia, suggesting that wakefulness during the drug’s acute effects was not necessary for this behavioral response.

30 Aug 2026

Starting statins early after diabetes diagnosis linked to lower dementia risk

Early initiation of statins after diagnosis of type 2 diabetes was associated with a lower risk of dementia, according to a study presented today at ESC Congress 2026 and published in The Lancet Regional Health – Europe.

30 Aug 2026

Oral relaxin agonist AZD5462 improves cardiac function in heart failure patients

The oral relaxin agonist, AZD5462, improved cardiac function in patients with chronic heart failure, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in Circulation.

30 Aug 2026

People with diabetes may have another reason to protect their cardiovascular health

Better cardiovascular health, measured using Life’s Essential 8, was associated with a lower risk of mild cognitive impairment among people with diabetes after accounting for genetic susceptibility. Associations with dementia varied by genetic risk, while higher LE8 scores were also linked to greater gray matter volume and lower white matter hyperintensity volume.

30 Aug 2026

Your skin may offer clues about how many fruits and vegetables you eat

In an exploratory study of 137 Australian adults, skin yellowness measured by reflectance spectroscopy was associated with combined fruit and vegetable intake, fruit intake alone, total carotenoid intake, body fat percentage and skin color. The findings suggest skin measurements could provide an objective dietary biomarker, but the researchers caution that skin color, ethnicity and other individual characteristics may influence how the measurements are interpreted.

30 Aug 2026

Breast cancer survivors could avoid lifelong heart medication, research suggests

Many breast cancer survivors whose treatment caused them to develop problems with their heart function can safely stop their medication after their heart recovers and most won't need to continue treatment long-term, according to a study funded by the British Heart Foundation and presented at the European Society of Cardiology Congress in Munich.

30 Aug 2026

Rapid pathway for diagnosing heart attacks does not improve emergency discharge rates

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Research News and Research

UC San Diego researchers win DARPA award to develop improved red blood cells

New BioTAK score accurately identifies Takotsubo syndrome before catheterization

New tool predicts heart failure treatment effects on blood pressure, kidney function and serum potassium

Night owls face tougher work-life balance and higher mental risks

Newly discovered lung immune cells could transform future flu vaccine design

Early cardiac monitoring reveals hidden arrhythmias in patients with unexplained fainting

Anticoagulation lowers subclinical leaflet thrombosis after TAVI procedure

Protein build-up may shape cancer drug response

A personalized elimination diet changed the gut microbiome in people with migraine

The scale told a similar story across three diets. The liver told a different one

Is there a best day to take GLP-1 drugs? Researchers looked for an answer

Does a psychedelic need an awake brain to have lasting effects? This mouse study offers a clue

Starting statins early after diabetes diagnosis linked to lower dementia risk

Oral relaxin agonist AZD5462 improves cardiac function in heart failure patients

People with diabetes may have another reason to protect their cardiovascular health

Your skin may offer clues about how many fruits and vegetables you eat

Breast cancer survivors could avoid lifelong heart medication, research suggests

Rapid pathway for diagnosing heart attacks does not improve emergency discharge rates

FDA approves daraxonrasib for patients with metastatic pancreatic cancer

Trial shows antiplatelet therapy needs personalization after stent implantation

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