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Genetic markers could help women with rheumatoid arthritis make informed decisions about pregnancy

When women with rheumatoid arthritis (RA) plan to become pregnant, many anguish over whether to stop their medications, risking a flareup in their disease, or continue with medication and risk possible harm to the baby.

6 Oct 2023

Drug overdose deaths disproportionately affect Americans without college education

Drug overdose deaths increased sharply among Americans without a college education and nearly doubled over a three-year period among those who don't have a high school diploma, according to a new RAND Corporation study.

6 Oct 2023

Bio-Rad Extends Range of Anti-Idiotypic Antibodies for Use in Preclinical and Clinical Drug Development

Bio-Rad Laboratories, a global leader in life science research and clinical diagnostics products, today extended its range of recombinant monoclonal anti-idiotypic antibodies with the introduction of six antibodies specific to dupilumab (Dupixent) and the addition of new evolocumab (Repatha), ipilimumab (Yervoy), and secukinumab (Cosentyx) antibodies.

From Bio-Rad Laboratories 6 Oct 2023

Trump misplaced blame when he said drug shortages were Biden’s fault

"Under 'Crooked Joe' Biden, there has been a catastrophic increase in shortages of essential medicines."

6 Oct 2023

New animal model replicates the development of cardiac sarcoidosis

Sarcoidosis is an inflammatory disease in which immune cells form tissue nodules in various organs, which can drastically impair organ function.

5 Oct 2023

How is TikTok's #Ozempic trend impacting diabetes patients?

A recent study analyzed TikTok videos with the hashtag "Ozempic," highlighting the platform's influence on promoting the weight loss drug. The surge in popularity resulted in medication shortages for diabetes patients, emphasizing the need for careful monitoring and collaboration among health professionals and social media platforms.

5 Oct 2023

GLP-1 weight loss drugs linked to heightened GI risks, says new study

Study from JAMA reveals that users of GLP-1 agonists, recent drugs for weight management, show a heightened risk of gastrointestinal complications like intestinal obstruction, gastroparesis, and pancreatitis. Though these effects are rare, those considering these drugs for weight loss should weigh the benefits against potential risks, especially if not using them for diabetes.

5 Oct 2023

New findings about nerve pathways to brown fat could lead to obesity treatments

A UCLA-led team of researchers has found nerve pathways that supply brown adipose tissue (BAT), a type of tissue that releases chemical energy from fat metabolism as heat – a finding that could pave the way toward using it to treat obesity and related metabolic conditions.

5 Oct 2023

Researchers spearhead a new method to hone in on new cancer drug targets

Searching for new ways to block the growth of cancer cells is like looking for a needle in a haystack. Tumor cells rely on thousands of proteins to function, but only a few of those proteins can be precisely targeted by drugs to treat cancer safely and effectively.

5 Oct 2023

Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

Researchers at Vanderbilt-Ingram Cancer Center have discovered a druggable target on natural killer cells that could potentially trigger a therapeutic response in patients with immunotherapy-resistant, triple-negative breast cancer.

5 Oct 2023

GLP-1 agonists linked to higher risk for gastrointestinal complications

They're being hailed as an effective way to lose weight, but diabetes drugs like Ozempic may come with a heightened risk of severe gastrointestinal problems.

5 Oct 2023

NCCN survey shows cancer drug shortages continue despite efforts

The National Comprehensive Cancer Network- a non-profit alliance of leading cancer centers across the United States - has released a follow-up survey on the ongoing chemotherapy shortages: 72% of the centers surveyed continue to experience a shortage of carboplatin and 59% are still seeing a shortage of cisplatin.

5 Oct 2023

Psychedelic therapy shows promise for treating veterans with PTSD and brain injury

One treatment each of two psychedelic drugs lowered depression and anxiety and improved cognitive functioning in a sample of U.S. special operations forces veterans who sought care at a clinic in Mexico, according to a new analysis of the participants' charts.

5 Oct 2023

Can falsified or substandard antimicrobials increase antimicrobial resistance?

The association between substandard or falsified (SF) antibiotics and antimicrobial resistance (AMR).

5 Oct 2023

ADHD found to increase crash risk among older driving adults

The association between ADHD and car crash risk among older adult drivers.

5 Oct 2023

Esketamine nasal spray superior in achieving remission in patients with treatment-resistant depression

Both severe depression and treatment-resistant depression are common. Up to one third of patients do not respond to conventional therapy with antidepressants such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs).

5 Oct 2023