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Chemists develop new approach based on graphene nanoflakes for drug delivery

Chemists funded by the SNSF have created a new compound for flexible drug delivery that specifically targets prostate cancer cells. Incorporating four different molecules, the compound prevents tumor cells from multiplying, can be detected by medical imaging and has staying power in the bloodstream.

19 Aug 2019

Molecular mechanism of enterovirus infection uncovered

Researchers from the Nanoscience Center at the University of Jyväskylä in collaboration with those at the University of Helsinki have found that body proteins called albumin and certain ions within the attacked host cells can affect the genetic workings of enteroviruses and enhance their infection.

19 Aug 2019

Research reveals physiological events leading to successful enterovirus infection

Enteroviruses are one of the most common human pathogens leading to high number of acute and chronic infections worldwide.

19 Aug 2019

Targeted pancreatic cancer drug shows promise in clinical trials

Researchers have conducted clinical trials with a new drug targeting pancreatic cancer and the initial results are promising.

16 Aug 2019

Boosting a single brain molecule can change 'dispositional anxiety' in nonhuman primates

Boosting a single molecule in the brain can change "dispositional anxiety," the tendency to perceive many situations as threatening, in nonhuman primates, researchers from the University of California, Davis, and the University of Wisconsin-Madison have found.

16 Aug 2019

Joint lubricating fluid triggers pain response from nerve cells in osteoarthritic patients

A team at the University of Cambridge has shown how, in osteoarthritis patients, the viscous lubricant that ordinarily allows our joints to move smoothly triggers a pain response from nerve cells similar that caused by chilli peppers.

14 Aug 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Bile pigment may play an unexpected role in protecting the brain

In studies in mice, Johns Hopkins Medicine researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting brain cells from damage from oxidative stress.

From Johns Hopkins Medicine 13 Aug 2019

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Physicians have long suspected that red blood cell transfusions given to premature infants with anemia may put them in danger of developing necrotizing enterocolitis, or NEC, a potentially lethal inflammatory disease of the intestines.

From Johns Hopkins Medicine 13 Aug 2019

SU2C Dream Team to develop new drug combination to stop spread of breast cancer

At a press conference at McGill University today, Stand Up To Cancer Canada, the Canadian Cancer Society, and the Canadian Institutes of Health Research announced the launch of the SU2C Canada Metastatic Breast Cancer Dream Team to pursue the development of a new drug combination that may help stop the spread of breast cancer to other organs of the body.

13 Aug 2019

New T cell detection method promises personalized immunotherapy for melanomas

An important new study shows that better T cell detection is now possible using revolutionary technology. T cells are a type of lymphocyte, which in turn belongs to the diverse family of immune cells. They take part in cancer fighting as well as in most other immune responses.

12 Aug 2019

Research shows that water molecules do not co-migrate via potassium channel

Do only potassium ions pass through the selectivity filter of a potassium channel, or are there water molecules between the ions? This question has been a source of controversy for years.

12 Aug 2019

Researchers identify direct toxic action of beta-amyloid in the brain

The brains of Alzheimer's patients who have already developed clinical symptoms contain large clumps of the protein beta-amyloid, known as plaques. Many therapeutic approaches focus on removing plaques, but such attempts have met with only limited success to date.

9 Aug 2019

New bimodal contrast agent suits both MRI and photoacoustic imaging

Magnetic resonance imaging visualizes internal body structures, often with the help of contrast agents to enhance sensitivity.

9 Aug 2019

Researchers test new drug to treat patients with chylomicronemia syndrome

People with familial chylomicronemia syndrome are born with a genetic mutation that means they can't produce an enzyme called lipoprotein lipase.

9 Aug 2019

Treatment with both targeted cancer therapy and MS drug halts glioblastoma stem cells

Glioblastoma is an aggressive form of brain cancer that infiltrates surrounding brain tissue, making it extremely difficult to treat with surgery.

9 Aug 2019

New method to enhance heart-attack repair using stem cell-derived cardiomyocytes

The heart cannot regenerate muscle tissue after a heart attack has killed part of the muscle wall. That dead tissue can strain surrounding muscle, leading to a lethal heart enlargement.

8 Aug 2019

Ultrasensitive method for direct detection of circulating tumor cells in blood

Tumor cells circulating in blood are markers for the early detection and prognosis of cancer. However, detection of these cells is challenging because of their scarcity.

8 Aug 2019

New initiative launched to support development and application of psychology research

In recent years, efforts to understand the workings of the mind have taken on new-found urgency. Not only are psychological and neurological disorders -- from Alzheimer's disease and strokes to autism and anxiety -- becoming more widespread, new tools and methods have emerged that allow scientists to explore the structure of, and activity within, the brain with greater granularity.

7 Aug 2019

Researchers discover promising approach to silence HIV infection

Researchers from The University of Texas Medical Branch at Galveston have discovered a new potential medication that works with an HIV-infected person's own body to further suppress the ever present but silent virus that available HIV treatments are unable to combat.

6 Aug 2019