Genome News and Research

RSS

New link found between Alzheimer's dementia and Dlgap2 gene

A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer's dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine.

23 Nov 2020

SARS-CoV-2's spike protein mutations have slowed, study finds

A team of researchers at the School of Information Sciences in Illinois, USA, has revealed the rate of mutation in the 29 proteins that make up the SARS-CoV-2 microbe.

23 Nov 2020

Leptin plays a strong role in controlling the body weight of children

Young children of African ancestry are more at risk of developing obesity if they possess a genetic variant that reduces their ability to produce the hormone leptin.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

Modified SARS-CoV-2 receptor-binding domain could increase vaccine efficacy, says study

A team of researchers from the USA and China have engineered a receptor-binding domain (RBD) that they claim improves the immunogenicity of multivalent SARS-CoV-2 vaccines. Their study, which was released on the bioRxiv* in November 2020, may help advance even more efficacious SARS-CoV-2 vaccine candidates in the future.

23 Nov 2020

Study on SARS-Cov2 genome may prepare scientists for future ‘SARS-CoV3’ viruses

The genetic code of the SARS-CoV2 virus is exactly 29,902 characters long, strung through a long RNA molecule. It contains information for the production of 27 proteins.

23 Nov 2020

Basic concepts lay the foundation for personalized immunotherapy

Personalized Immunotherapy for Tumor Diseases and Beyond introduces personalized immunotherapy with multi-dimensional models of analysis to determine the best plan for the immunotherapy of patients.

23 Nov 2020

Analysis shows social distancing helped reduce nosocomial SARS-CoV-2 transmission in London

Recently, a team of researchers from the King's College London, Guy's and St Thomas' NHS Foundation Trust, and St Thomas' Hospital, London analyzed comprehensive epidemiological and viral nanopore sequence data from 574 patients with SARS-CoV-2 infection confirmed by a PCR test in March 2020.

22 Nov 2020

Researchers receive $8.3 million NIH grant to illuminate the causes of spina bifida

Researchers at University of California San Diego School of Medicine, in collaboration with Rady Children's Institute for Genomic Medicine, have been awarded a five-year, $8.3 million grant from the National Institutes of Health's Eunice Kennedy Shriver National Institute of Child Health and Human Development to further illuminate the causes of spina bifida, the most common structural defect of the central nervous system.

20 Nov 2020

Scientists explain potential reasons for SARS-CoV-2 re-infection

A study, which was published in the journal New Microbes and New Infections, focused on the possible reasons for SARS-CoV-2 reinfection.

20 Nov 2020

Cannabis use disorder may increase risk of COVID-19 hospitalization

Researchers in the United States have conducted a study suggesting that genetic vulnerability to a psychiatric syndrome called cannabis use disorder (CUD) may increase the risk of developing severe coronavirus disease 2019 (COVID-19) that requires hospitalization.

19 Nov 2020

Genetic variations of SARS-CoV-2 transmission in cats

Using cats as an animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, researchers have determined the virus has a narrow transmission bottleneck.

19 Nov 2020

How the influenza virus takes control of a city, and implications for SARS-CoV-2

SARS-CoV-2 has spread around the world, passed across the borders of nations by travelers and cargo.

19 Nov 2020

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer.

19 Nov 2020

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.

18 Nov 2020

Researchers use single-cell analysis to assess effects of aging on mice’s egg cells

Using the power of single-cell analysis, researchers at the Babraham Institute have assessed the effects of age on egg cells (oocytes) in mice, particularly looking to identify genomic and epigenetic factors that relate to reduced developmental competence.

18 Nov 2020

New understanding of glycan signatures of the SARS-COV-2 S1 spike protein

A team of scientists from the University of Oxford, UK, has revealed that site-specific glycosylation differs between spike proteins derived from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a viral vector-based vaccine candidate.

18 Nov 2020

Optimizing SARS-COV-2 inactivation for COVID-19 research at lower biosafety levels

Researchers at Montana State University have validated and compared two methods for inactivating the causative agent of coronavirus disease 2019 (COVID-19) that would enable the virus to be studied at a lower biosafety level (BSL) than the one currently required.

18 Nov 2020

Examining potential foodborne transmission of SARS-CoV-2 through fresh produce

To address this gap in knowledge, researchers from the Bureau of Microbial Hazards, Health Canada, and Faculty of Medicine, University of Ottawa examined the survival of human coronaviruses on the surface of fresh produce such as apples, cucumbers, and tomatoes.

18 Nov 2020

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Researchers at Baylor College of Medicine, the Broad Institute of MIT and Harvard and other institutions have applied powerful proteogenomics approaches to better understand the biological complexity of breast cancer.

18 Nov 2020

Genome News and Research

New link found between Alzheimer's dementia and Dlgap2 gene

SARS-CoV-2's spike protein mutations have slowed, study finds

Leptin plays a strong role in controlling the body weight of children

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

Modified SARS-CoV-2 receptor-binding domain could increase vaccine efficacy, says study

Study on SARS-Cov2 genome may prepare scientists for future ‘SARS-CoV3’ viruses

Basic concepts lay the foundation for personalized immunotherapy

Analysis shows social distancing helped reduce nosocomial SARS-CoV-2 transmission in London

Researchers receive $8.3 million NIH grant to illuminate the causes of spina bifida

Scientists explain potential reasons for SARS-CoV-2 re-infection

Cannabis use disorder may increase risk of COVID-19 hospitalization

Genetic variations of SARS-CoV-2 transmission in cats

How the influenza virus takes control of a city, and implications for SARS-CoV-2

CRISPR/Cas9 system is highly effective in treating metastatic cancers

TB researchers uncover crucial clue that explains antibiotic resistance in bacteria

Researchers use single-cell analysis to assess effects of aging on mice’s egg cells

New understanding of glycan signatures of the SARS-COV-2 S1 spike protein

Optimizing SARS-COV-2 inactivation for COVID-19 research at lower biosafety levels

Examining potential foodborne transmission of SARS-CoV-2 through fresh produce

Researchers use proteogenomics to better understand the biological complexity of breast cancer

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News