Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Molecular simulations reveal detailed structure and dynamics of SARS-CoV-2 spike protein

Recently, researchers reported a study in which they analyzed the structure and dynamics of the spike protein using multiple molecular dynamic simulations. Their study is published on the preprint server bioRxiv.

19 Oct 2020

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

The COVID-19 pandemic has led to intensive scientific efforts to bring about an effective vaccine for global distribution. Many different vaccine design approaches are underway. A recent study published in the journal The Lancet Infectious Diseases in October 2020 reports a potentially successful inactivated virus vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Oct 2020

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Now, a new study presented on the preprint server bioRxiv in October 2020 describes the efficient design of an mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), based on the use of the viral receptor-binding domain (RBD) mRNA encapsulated in lipid nanoparticles (LNP).

19 Oct 2020

Antigenic imprinting of sarbecovirus

A recent study published on the preprint server bioRxiv* in October 2020 shows that the design of a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) must consider the prior history of exposure to coronaviruses since these affect the antibody response to the virus.

19 Oct 2020

New lab test for detection of SARS-CoV-2 antibodies gives results more quickly than existing assays

Knowing you have developed antibodies against the SARS-CoV-2 virus after recovering from COVID-19 doesn't tell you everything about your immunity.

19 Oct 2020

Immunoglobulin M ACE2 autoantibodies associated with severe COVID-19

As the COVID-19 pandemic progresses with little prospect of immediate relief, a recent study by Johns Hopkins University researchers published on the preprint server medRxiv* in October 2020 discusses the association of Immunoglobulin M (IgM) autoantibodies against the host receptor that binds severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with severe disease via vascular endothelial damage. This could help develop better therapies and prognostic criteria.

19 Oct 2020

KNAUER subsidiary 'Das Labor. GmbH' produces SARS-CoV-2 antibody rapid tests in Africa

‘KNAUER Wissenschaftliche Geräte GmbH’ and its new subsidiary 'Das Labor. GmbH' produce reliable Corona antibody tests in Sub-Saharan Africa.

From KNAUER Wissenschaftliche Geräte GmbH 19 Oct 2020

Sinopharm's candidate SARS-CoV-2 vaccine BBIBP-CorV shows promise in clinical trials

Researchers in China have conducted a phase 1/2 trial demonstrating the safety, tolerability, and immunogenicity of a candidate vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

18 Oct 2020

Antibody levels drop rapidly in recovering COVID-19 patients, shows study

In the absence of approved, effective treatments for COVID-19, some hospitals have been treating patients with severe COVID symptoms with blood plasma from recovering patients.

16 Oct 2020

New diagnostic test detects and identifies SARS-CoV-2 virus in less than five minutes

Scientists from Oxford University’s Department of Physics have developed an extremely rapid diagnostic test that detects and identifies viruses in less than five minutes.

16 Oct 2020

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

Now, a recent study published on the preprint server bioRxiv in October 2020 reports the development of a rapid process for generating high-affinity mouse mAbs, and their functional attributes.

16 Oct 2020

High-titer convalescent plasma reduced COVID-19 symptom severity in green monkeys

As scientists scramble to find effective vaccines and antivirals for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a recent study published on the preprint server bioRxiv in October 2020 reports that the use of convalescent plasma to treat COVID-19 disease early in the course of the illness may be among the best available strategies at present.

16 Oct 2020

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

The COVID-19 pandemic is threatening to come back in greater intensity during the winter and fall. Faced with this threat, vaccine development efforts are entering a phase of renewed focus, attempting to identify antigens capable of eliciting protective levels of neutralizing antibodies. A new study published on the preprint server bioRxiv* in October 2020 reports on a novel mRNA vaccine candidate's performance in two animal models.

16 Oct 2020

Previous infections with seasonal coronaviruses might protect against SARS-CoV-2

Seasonal coronaviruses, which generally cause mild respiratory illness and symptoms of the common cold, belong to the same viral family as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes COVID-19.

15 Oct 2020

Obese persons have greater risk of developing severe COVID-19

The probability that an obese person will develop severe COVID-19 is high regardless of age, sex, ethnicity, and the presence of co-morbidities such as diabetes, high blood pressure, and heart or lung disease, according to a study by Brazilian researchers published in Obesity Research & Clinical Practice.

15 Oct 2020

Capillary blood microsampling could prove a breakthrough in SARS-CoV-2 serosurveillance

As COVID-19 seems to be making a comeback in many areas of the world, including Japan, a new study published on the preprint server medRxiv in October 2020 shows the relevance of microsamples of blood in serosurveillance of this disease.

15 Oct 2020

Rapid SARS‐CoV‐2 IgM‐IgG combined antibody test

A recent study published on the preprint server medRxiv in October 2020 reports a new diagnostic test for SARS-CoV-2 based on the detection of antibodies.

15 Oct 2020

Human bivalent SARS-CoV-2 neutralizing antibodies more potent

A recent study published on the preprint server bioRxiv in October 2020 reports more effective viral neutralization by bivalent anti-spike antibodies. This could promote the development of better therapeutics and vaccines.

15 Oct 2020

The COVID-19 vaccine pipeline

Researchers from Mayo Clinic, United States of America, have reviewed the immunity developed against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease.

14 Oct 2020

FDA approves Regeneron antibody drug as first treatment for Ebola virus

Today, the U.S. Food and Drug Administration approved Inmazeb (atoltivimab, maftivimab, and odesivimab-ebgn), a mixture of three monoclonal antibodies, as the first FDA-approved treatment for Zaire ebolavirus (Ebola virus) infection in adult and pediatric patients.

14 Oct 2020

Antibody News and Research

Further Reading

Molecular simulations reveal detailed structure and dynamics of SARS-CoV-2 spike protein

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Antigenic imprinting of sarbecovirus

New lab test for detection of SARS-CoV-2 antibodies gives results more quickly than existing assays

Immunoglobulin M ACE2 autoantibodies associated with severe COVID-19

KNAUER subsidiary 'Das Labor. GmbH' produces SARS-CoV-2 antibody rapid tests in Africa

Sinopharm's candidate SARS-CoV-2 vaccine BBIBP-CorV shows promise in clinical trials

Antibody levels drop rapidly in recovering COVID-19 patients, shows study

New diagnostic test detects and identifies SARS-CoV-2 virus in less than five minutes

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

High-titer convalescent plasma reduced COVID-19 symptom severity in green monkeys

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

Previous infections with seasonal coronaviruses might protect against SARS-CoV-2

Obese persons have greater risk of developing severe COVID-19

Capillary blood microsampling could prove a breakthrough in SARS-CoV-2 serosurveillance

Rapid SARS‐CoV‐2 IgM‐IgG combined antibody test

Human bivalent SARS-CoV-2 neutralizing antibodies more potent

The COVID-19 vaccine pipeline

FDA approves Regeneron antibody drug as first treatment for Ebola virus

Using single B cell screening to boost antibody discovery eBook

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