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Research sheds new light on how the CRISPR immune system evolved

With new insights into how the genetic tool CRISPR - which allows direct editing of our genes - evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.

25 Nov 2020

Genomic analysis provides clues about SARS-CoV-2 ancestry and transmission

Researchers in the UK conducting a genomic analysis of severe acute respiratory virus syndrome coronavirus 2 (SARS-CoV-2) and SARS-like coronaviruses in the bat and pangolin have identified strong host-associated divergences that could provide clues about the ancestry and interspecies transmission of SARS-CoV-2.

25 Nov 2020

Researchers discover close SARS-CoV-2-relative in animal hosts outside China

In a major new discovery that might deepen our understanding of SARS-CoV-2’s animal origins and its genetic evolution, coronaviruses very closely related to SARS-CoV-2 have been discovered in two horseshoe bats outside of China.

25 Nov 2020

Computational model can help predict cellular drug targets against COVID-19

A computational model of a human lung cell has been used to understand how SARS-CoV-2 draws on human host cell metabolism to reproduce by researchers at the University of Warwick.

25 Nov 2020

Long-range regulation of tumor suppressor genes plays key role in cancer

Enhancers are regulatory elements that play an important role in cancer.Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, identified a novel enhancer.

25 Nov 2020

UC Santa Cruz teams up to launch a web portal for people at risk of heritable stomach cancers

Coinciding with Stomach Cancer Awareness Month in November, the UC Santa Cruz Genomics Institute is teaming up with the patient advocacy nonprofit No Stomach For Cancer to release a web portal designed to help researchers identify individuals at risk of heritable stomach cancers.

24 Nov 2020

The role of micro-RNA in SARS-CoV-2 infection and COVID-19

A team of researchers based in Iran have explored the role of micro-RNA in COVID-19. Their study titled, “The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,” was published in the latest issue of the journal International Immunopharmacology.

24 Nov 2020

Scientists show SARS-CoV-2's viral replication with 3D integrative imaging

A team of researchers at Heidelberg University in Germany have performed a detailed imaging analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to determine how the virus reprograms infected cells.

24 Nov 2020

SARS-CoV-2's RNA folding structures are potential therapeutic targets, study finds

A team of researchers at Goethe University in Germany has observed the RNA folding structures of the SARS-CoV-2 genome that aids the infection process.

24 Nov 2020

Research provides key information on transmission, development of mutations in SARS-CoV-2 virus

In the COVID-19 pandemic, 57 million people have already been infected worldwide. In the search for vaccines and therapies, a precise understanding of the virus, its mutations, and transmission mechanisms are crucial.

24 Nov 2020

Researchers develop new search engine to investigate viral sequences in COVID-19

Since the beginning of 2020, labs from all around the world are sequencing the material from positive tests of people affected by COVID-19 and then depositing sequences mostly to three points of collection: GenBank, COG-UK, and GISAID.

23 Nov 2020

Study shows BICRA gene functions in neural development in humans, flies

Physicians and scientists are constantly on the lookout for new disease genes that can help them understand why patients have undiagnosed medical problems.

23 Nov 2020

New link found between Alzheimer's dementia and Dlgap2 gene

A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer's dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine.

23 Nov 2020

SARS-CoV-2's spike protein mutations have slowed, study finds

A team of researchers at the School of Information Sciences in Illinois, USA, has revealed the rate of mutation in the 29 proteins that make up the SARS-CoV-2 microbe.

23 Nov 2020

Leptin plays a strong role in controlling the body weight of children

Young children of African ancestry are more at risk of developing obesity if they possess a genetic variant that reduces their ability to produce the hormone leptin.

23 Nov 2020

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

A thought-provoking new study reports that the anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike antibodies elicited by natural infection may not be able to neutralize emerging strains that display deletion mutations in their genomic RNA.

23 Nov 2020

Modified SARS-CoV-2 receptor-binding domain could increase vaccine efficacy, says study

A team of researchers from the USA and China have engineered a receptor-binding domain (RBD) that they claim improves the immunogenicity of multivalent SARS-CoV-2 vaccines. Their study, which was released on the bioRxiv* in November 2020, may help advance even more efficacious SARS-CoV-2 vaccine candidates in the future.

23 Nov 2020

Study on SARS-Cov2 genome may prepare scientists for future ‘SARS-CoV3’ viruses

The genetic code of the SARS-CoV2 virus is exactly 29,902 characters long, strung through a long RNA molecule. It contains information for the production of 27 proteins.

23 Nov 2020

Basic concepts lay the foundation for personalized immunotherapy

Personalized Immunotherapy for Tumor Diseases and Beyond introduces personalized immunotherapy with multi-dimensional models of analysis to determine the best plan for the immunotherapy of patients.

23 Nov 2020

Analysis shows social distancing helped reduce nosocomial SARS-CoV-2 transmission in London

Recently, a team of researchers from the King's College London, Guy's and St Thomas' NHS Foundation Trust, and St Thomas' Hospital, London analyzed comprehensive epidemiological and viral nanopore sequence data from 574 patients with SARS-CoV-2 infection confirmed by a PCR test in March 2020.

22 Nov 2020

Genome News and Research

Research sheds new light on how the CRISPR immune system evolved

Genomic analysis provides clues about SARS-CoV-2 ancestry and transmission

Researchers discover close SARS-CoV-2-relative in animal hosts outside China

Computational model can help predict cellular drug targets against COVID-19

Long-range regulation of tumor suppressor genes plays key role in cancer

UC Santa Cruz teams up to launch a web portal for people at risk of heritable stomach cancers

The role of micro-RNA in SARS-CoV-2 infection and COVID-19

Scientists show SARS-CoV-2's viral replication with 3D integrative imaging

SARS-CoV-2's RNA folding structures are potential therapeutic targets, study finds

Research provides key information on transmission, development of mutations in SARS-CoV-2 virus

Researchers develop new search engine to investigate viral sequences in COVID-19

Study shows BICRA gene functions in neural development in humans, flies

New link found between Alzheimer's dementia and Dlgap2 gene

SARS-CoV-2's spike protein mutations have slowed, study finds

Leptin plays a strong role in controlling the body weight of children

SARS-CoV-2 spike deletion mutations may evade current vaccine candidates, study finds

Modified SARS-CoV-2 receptor-binding domain could increase vaccine efficacy, says study

Study on SARS-Cov2 genome may prepare scientists for future ‘SARS-CoV3’ viruses

Basic concepts lay the foundation for personalized immunotherapy

Analysis shows social distancing helped reduce nosocomial SARS-CoV-2 transmission in London

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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