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Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

Deactivating the cancer-causing protein by cutting off other proteins that activate it

In a line of dominos, if you take out a single piece, the last one will never fall. Similarly, a lot of pieces have to line up and be pushed at the same time in a cell to result in cancer.

1 Dec 2021

Researchers identify new drug that makes pancreatic cancer cells more vulnerable to chemotherapy

Researchers at Washington University School of Medicine in St. Louis have identified a drug compound that makes pancreatic cancer cells more vulnerable to chemotherapy.

1 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio 1 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

30 Nov 2021

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Immunotherapies have shown striking clinical benefit in the treatment of many cancers, especially when used in combination with chemotherapy.

30 Nov 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

New combination treatment enables complete tumor regression in mice with high-risk neuroblastoma

In mice with high-risk neuroblastoma, tumors disappeared in response to a new combination treatment with precision medicines, a recent study from University of Gothenburg researchers shows.

30 Nov 2021

New safe, painless diagnostic tool for detecting breast cancer

Mammograms are a safe, effective way to detect the presence of breast cancer in women. But doctors recommend most females should start getting mammograms after the age of 40 in part because the procedure involves small doses of ionizing radiation.

30 Nov 2021

Imaging drug that illuminates ovarian cancer tissue when exposed to fluorescent light gets FDA approval

The U.S. Food and Drug Administration (FDA) today approved an imaging drug known as Cytalux (pafolacianine), which is attracted to ovarian cancer tissue and illuminates it when exposed to fluorescent light, allowing surgeons to more easily find and more precisely remove the cancer.

30 Nov 2021

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Funded by a Specialized Program of Research Excellence award from the National Cancer Institute (NCI), the Kidney Cancer Program at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

29 Nov 2021

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Pancreatic cancer is very aggressive and, unfortunately, has a poor prognosis with a 5-year survival of only 5%. Most deaths related to pancreatic cancer are due to metastasis, which occurs when the tumour invades other organs.

29 Nov 2021

New mechanism involved in early melanoma metastasis discovered

How tumors manipulate their environment to advance is one of the big questions that Peinado has been trying to answer for years.

25 Nov 2021

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

A combination of two targeted cancer drugs showed unprecedented, "clinically meaningful" activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.

25 Nov 2021

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

LMU immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.

25 Nov 2021

Direct-acting antivirals for HCV-related hepatocellular carcinoma reduces the risk of tumor progression

In a new cohort study of patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), a disease with a high recurrence rate, researchers at the Osaka City University Graduate School of Medicine reported that after receiving cancer treatment, the oral administration of direct-acting antivirals (DAA) reduces the risk of tumor progression following recurrence of the liver disease.

25 Nov 2021

Scientists use the synchrotron to better understand structure of cancer cells

A team of scientists led by the University of Surrey have used a special particle accelerator facility known as a synchrotron to better understand the structure of cancer cells.

25 Nov 2021

New, improved organoids shed light on untreatable form of prostate cancer

A multi-institutional team of investigators led by bioengineer Ankur Singh has developed research tools that shed new light on a virtually untreatable form of prostate cancer, opening a pathway that may lead to novel therapeutics and a glimmer of hope for patients.

24 Nov 2021

Tumor News and Research

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Deactivating the cancer-causing protein by cutting off other proteins that activate it

Researchers identify new drug that makes pancreatic cancer cells more vulnerable to chemotherapy

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

Novel anti-inflammatory drug target identified by CRISPR

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

New combination treatment enables complete tumor regression in mice with high-risk neuroblastoma

New safe, painless diagnostic tool for detecting breast cancer

Imaging drug that illuminates ovarian cancer tissue when exposed to fluorescent light gets FDA approval

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

New mechanism involved in early melanoma metastasis discovered

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

Direct-acting antivirals for HCV-related hepatocellular carcinoma reduces the risk of tumor progression

Scientists use the synchrotron to better understand structure of cancer cells

New, improved organoids shed light on untreatable form of prostate cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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