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Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

A drug combination designed to enhance the immune system's ability to zero in and attack cancer cells has shown a pronounced therapeutic effect against advanced and metastatic cancers in mice, according to a Mayo Clinic study, published in the July 12 edition of the online journal Oncotarget.

12 Jul 2016

Study shows how increase in BMI contributes to multiple myeloma growth and progression

In a new study published in Cancer Letters, American University researchers show how, as body mass index increases, so does the growth and spread of the blood cancer multiple myeloma, which accounts for about 10 percent of all blood cancers in patients.

12 Jul 2016

Machine learning can improve autism screening and diagnostics

Approximately one in 68 people are on the autism spectrum. Experts are unanimous on this: early intervention is critical for improving communication skills and addressing behavioral issues.

12 Jul 2016

Phase III clinical study of promising prostate cancer drug reveals surprising results

A recently published international clinical Phase III trial of a promising drug for treating advanced prostate cancer ended with surprising results: the new therapeutic agent failed to achieve any significant improvement in the overall survival of patients compared with the established standard treatment.

12 Jul 2016

Innovative organ donation program allows living donors to donate kidney in advance

Gift certificate, layaway plan or voucher. Call it what you want, but an innovative organ donation program initiated at UCLA has started to spread to other transplant programs across the United States.

11 Jul 2016

Gut bacteria can help predict susceptibility to rheumatoid arthritis

The bacteria in your gut do more than break down your food. They also can predict susceptibility to rheumatoid arthritis, suggests Veena Taneja, Ph.D., an immunologist at Mayo Clinic's Center for Individualized Medicine. Dr. Taneja recently published two studies — one in Genome Medicine and one in Arthritis and Rheumatology — connecting the dots between gut microbiota and rheumatoid arthritis.

11 Jul 2016

JAX researchers find precise, reliable way to identify leukemia cells of origin

Every cancer starts with a single cell, and Jackson Laboratory researchers have found a precise and reliable way -- whole-genome profiling of open chromatin -- to identify the kind of cell that leads to a given case of leukemia, a valuable key to cancer prognosis and outcome.

11 Jul 2016

Scientists reveal how common symptomless condition can develop into myeloma

Researchers from the University of Birmingham and hospitals across the West Midlands have revealed how a common symptomless condition can develop into the blood cancer myeloma.

11 Jul 2016

Deadly bacteria can travel to the brain and spinal cord in 24 hours, new study finds

A deadly bacteria that can be picked up by a simple sniff can travel to the brain and spinal cord in just 24 hours, a new Griffith University and Bond University study has found.

11 Jul 2016

Study suggests final fusion surgery in children with early-onset scoliosis can be eliminated

In a look-back study of medical records, researchers at Johns Hopkins Medicine concluded that a major operation to fuse the spines of children with a rare form of severe, early-onset scoliosis can be eliminated in many cases.

8 Jul 2016

Location of UCL tears can be key to predicting success of non-operative treatment in MLB pitchers

Ulnar collateral ligament (UCL) injuries in Major League Baseball (MLB) pitchers are high-impact due to player time lost and the resulting effect on teams and an athlete's career, making treatment decisions an even greater challenge for physicians.

7 Jul 2016

Study shows twice daily exercise intervention improves bone strength in VLBW pre-term infants

Because of their low weight and premature birth, very low birth weight (VLBW) pre-term infants have lower bone mineral mass and a greater need for bone nutrients compared to most new-born infants.

7 Jul 2016

Watching TV for long hours during childhood linked to lower bone mineral content

Consistently watching high levels of television during childhood and adolescence were linked with lower peak bone mass at age 20 years in a recent study.

7 Jul 2016

Inherited mutations in DNA repair genes may predispose to metastatic prostate cancer

Inherited mutations in genes that function to repair DNA may contribute to metastatic prostate cancer more than previously recognized, according to a study out today in the New England Journal of Medicine.

7 Jul 2016

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Researchers from the University of Zurich and University Children's Hospital Zurich have discovered the first X-chromosome-inherited type of the congenital disease osteogenesis imperfecta, also known as brittle-bone disease.

6 Jul 2016

Menopause symptoms: can a healthcare professional help? An interview with Dr Heather Currie

The survey showed that only 50% of women consulted a healthcare professional about their symptoms, despite the fact that many women said their symptoms were having a significant effect on their work life, social life, home life and sex life.

6 Jul 2016

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses.

6 Jul 2016

Scientists discover new genetic variations linked to increased myeloma risk

Researchers have identified eight new genetic variations in the human genome that could be linked to an increased risk of developing myeloma. The findings provide additional evidence and build on existing research that suggests myeloma can run in families.

5 Jul 2016

Study could offer new ways to enhance cancer immunotherapy

When an immune T cell divides into two daughter cells, the activity of an enzyme called mTORC1, which controls protein production, splits unevenly between the progeny, producing two cells with different properties.

4 Jul 2016

Risk of blindness from spinal-fusion surgery has declined, study shows

The risk of blindness caused by spinal fusion, one of the most common surgeries performed in the U.S., has dropped almost three-fold since the late 1990s, according to the largest study of the topic to date.

1 Jul 2016

Bone News and Research

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

Study shows how increase in BMI contributes to multiple myeloma growth and progression

Machine learning can improve autism screening and diagnostics

Phase III clinical study of promising prostate cancer drug reveals surprising results

Innovative organ donation program allows living donors to donate kidney in advance

Gut bacteria can help predict susceptibility to rheumatoid arthritis

JAX researchers find precise, reliable way to identify leukemia cells of origin

Scientists reveal how common symptomless condition can develop into myeloma

Deadly bacteria can travel to the brain and spinal cord in 24 hours, new study finds

Study suggests final fusion surgery in children with early-onset scoliosis can be eliminated

Location of UCL tears can be key to predicting success of non-operative treatment in MLB pitchers

Study shows twice daily exercise intervention improves bone strength in VLBW pre-term infants

Watching TV for long hours during childhood linked to lower bone mineral content

Inherited mutations in DNA repair genes may predispose to metastatic prostate cancer

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Menopause symptoms: can a healthcare professional help? An interview with Dr Heather Currie

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Scientists discover new genetic variations linked to increased myeloma risk

Study could offer new ways to enhance cancer immunotherapy

Risk of blindness from spinal-fusion surgery has declined, study shows

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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