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BU researchers receive NIH grant to identify genetic factors for Alzheimer's disease

The National Institutes of Health/National Institute on Aging recently awarded a $13.7 million grant to a project led by Boston University Chobanian & Avedisian School of Medicine principal investigators Lindsay Farrer, PhD, chief of biomedical genetics and distinguished professor of genetics, and Richard Sherva, PhD, assistant professor of medicine in biomedical genetics, for research using whole genome sequencing and other approaches to identify genetic factors for Alzheimer disease (AD) in Jews currently living in Israel who trace their ancestors to southern Spain and locations in the Middle East and North Africa (MENA) and Arab citizens of Israel.

15 Sep 2023

California Legislature passes Gov. Newsom’s proposal to retool mental health services act

The California Legislature passed a pair of bills greenlighting Gov. Gavin Newsom's campaign to build 10,000 new beds and housing units and increase drug addiction treatment as part of his response to the state's homelessness and drug crises.

15 Sep 2023

Chemotherapy drug could be repurposed to treat fatal heart failure, computer model suggests

A chemotherapy drug used to fight bone-marrow cancer also has the potential to treat and prevent potentially deadly heart failure, a powerful new drug-screening tool developed at UVA Health suggests.

15 Sep 2023

New intrauterine device is highly effective in managing postpartum bleeding

A study led by Columbia obstetricians has shown that a new intrauterine device can rapidly control postpartum hemorrhage, a major cause of severe maternal morbidity and death, in real-world situations.

14 Sep 2023

Research opens up new directions to develop drugs for stopping cytokine storms

Constant exposure of cells to stressing agents, such as pathogens, may disturb an organism's normal functioning. To fight stress, cells have developed several coping mechanisms, including the inflammatory response.

14 Sep 2023

MIT study reveals why immunotherapy doesn't work for all cancer patients

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14 Sep 2023

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Patients with stage 1–3 non-small cell lung cancer (NSCLC) given a combination immunotherapy prior to surgery (neoadjuvant) had a better major pathological response (10% or less residual cancer) when the cancer was removed than those who took a single immunotherapy agent alone, according to results of a novel multicenter phase 2 NeoCOAST platform trial that included two investigators from the Johns Hopkins Kimmel Cancer Center and its Bloomberg-Kimmel Institute for Cancer Immunotherapy.

14 Sep 2023

Multi-omics study offers insights into psoriasis treatment

Researchers use a multi-omics approach combining immune cell-enriched scRNA-seq, microarray analysis, and immunohistochemistry to elucidate the translational role of anti-IL-17A in suppressing the autoimmune functions of T17 cells, thereby effectively treating human psoriasis.

14 Sep 2023

The anti-metastatic and anti-proliferation impact of dandelion extract on breast cancer cells

Researchers evaluated the anti-metastatic and anti-proliferative properties of all-trans retinoic acid (ATRA) and dandelion extract in breast cancer cells.

14 Sep 2023

AACR Cancer Progress Report provides latest statistics on cancer research and treatment

Today, the American Association for Cancer Research (AACR) released the 13th edition of its annual Cancer Progress Report, which chronicles how basic, translational, and clinical cancer research and cancer-related population sciences - primarily supported by federal investments in the National Institutes of Health (NIH) and the National Cancer Institute (NCI) - remain vitally important to improving health and saving lives.

13 Sep 2023

New trial aims to reduce infection and blood clot rates for kids with cancer

A trial aiming to reduce infection and blood clot rates for children with cancer is being led by The University of Queensland across Brisbane, Sunshine Coast and Gold Coast hospitals.

13 Sep 2023

International experts discuss recent advances in the diagnosis and treatment of atrial fibrillation

Recent advances in the diagnosis and treatment of atrial fibrillation, and what they mean for patients, were considered by a group of around 75 international experts at a three-day meeting that began on Monday.

13 Sep 2023

Unhealthy pathobiome in the brain could cause some forms of Alzheimer's and related dementias

The human microbiome includes the genetic material of more than 100 trillion tiny microorganisms – fungi, yeast, bacteria, and even viruses, most of which hang out in our gastrointestinal tract to serve as guardians of our health.

13 Sep 2023

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops.

13 Sep 2023

Kuano closes £1.8M seed funding round to validate quantum simulation platform for drug discovery

Kuano, a drug discovery company combining quantum mechanics with AI to design the next generation of medicines, today announced the close of its £1.8M seed funding round, led by Mercia Ventures, and including ACF Investors, Ascension Ventures, o2h Ventures, Meltwind Advisory LLP, and other Angel investors.

From Kuano Ltd. 13 Sep 2023

A combination of inhibitors may suppress tumor growth and prevent cancer relapse

An international team of researchers has demonstrated that a combination of inhibitors may suppress tumor growth and prevent relapse in patients with certain cancers, including head and neck squamous cell carcinoma and lung adenocarcinoma.

12 Sep 2023

Study reveals potential targets to improve the treatment of myeloma

A ground-breaking study by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has revealed crucial insights into the role of the histone methyltransferase NSD2 and its epigenetic target PKCα in causing t(4;14) translocated multiple myeloma (MM), a high-risk subtype of blood cancer, to be more aggressive and resistant to treatment.

12 Sep 2023

Natural compound in turmeric may be as effective as omeprazole for treating indigestion

A natural compound found in the culinary spice turmeric may be as effective as omeprazole - a drug used to curb excess stomach acid - for treating indigestion symptoms, suggests the first study of its kind, published online in the journal BMJ Evidence-Based Medicine.

12 Sep 2023

Stem cells can be used to repair damaged lung tissue in COPD patients

For the first time, researchers have shown it is possible to repair damaged lung tissue in patients with chronic obstructive pulmonary disease (COPD) using the patients' own lung cells.

12 Sep 2023

New class of iron-targeting compounds found to hamper proliferation of cancer cells

Researchers at the University of Arizona Cancer Center discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting.

12 Sep 2023

Drugs News and Research

BU researchers receive NIH grant to identify genetic factors for Alzheimer's disease

California Legislature passes Gov. Newsom’s proposal to retool mental health services act

Chemotherapy drug could be repurposed to treat fatal heart failure, computer model suggests

New intrauterine device is highly effective in managing postpartum bleeding

Research opens up new directions to develop drugs for stopping cytokine storms

MIT study reveals why immunotherapy doesn't work for all cancer patients

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Multi-omics study offers insights into psoriasis treatment

The anti-metastatic and anti-proliferation impact of dandelion extract on breast cancer cells

AACR Cancer Progress Report provides latest statistics on cancer research and treatment

New trial aims to reduce infection and blood clot rates for kids with cancer

International experts discuss recent advances in the diagnosis and treatment of atrial fibrillation

Unhealthy pathobiome in the brain could cause some forms of Alzheimer's and related dementias

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

Kuano closes £1.8M seed funding round to validate quantum simulation platform for drug discovery

A combination of inhibitors may suppress tumor growth and prevent cancer relapse

Study reveals potential targets to improve the treatment of myeloma

Natural compound in turmeric may be as effective as omeprazole for treating indigestion

Stem cells can be used to repair damaged lung tissue in COPD patients

New class of iron-targeting compounds found to hamper proliferation of cancer cells

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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