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Research investigates how drug-eluting stent affects arterial tissue permeability and blood flow

For patients with symptomatic coronary artery disease, the best course of action often involves implanting a drug-eluting stent into the artery where a plaque buildup is blocking blood flow to the heart.

2 Sep 2021

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

1 Sep 2021

New AI technology for heart imaging could improve care for patients

A new artificial-intelligence technology for heart imaging can potentially improve care for patients, allowing doctors to examine their hearts for scar tissue while eliminating the need for contrast injections required for traditional cardiovascular magnetic resonance imaging (CMR).

1 Sep 2021

Studies outlines novel strategies for detecting cancer and minimal residual disease

The latest special issue of PLOS Medicine features five studies outlining novel strategies for detecting cancer and for identifying minimal residual disease - when a small number of tumor cells survive treatment, potentially leading to recurrence of cancer.

1 Sep 2021

Blood test could enable early detection of cancer in people with neurofibromatosis type 1

People with an inherited condition known as neurofibromatosis type 1, or NF1, often develop non-cancerous, or benign, tumors that grow along nerves. These tumors can sometimes turn into aggressive cancers, but there hasn't been a good way to determine whether this transformation to cancer has happened.

31 Aug 2021

$1.3 million in NIH funding to enable drug delivery technology research

Two National Institute of Health grants totaling over $1.3 million will enable research into antibody-mediated drug delivery technology for the treatment of cancer and autoimmune disorders. L. Nathan Tumey, assistant professor of pharmaceutical sciences at Binghamton University, State University of New York, is the Principal Investigator on both grants - $1.2 million from the National Institute of General Medical Sciences and $150,000 from the National Institute of Allergy and Infectious Diseases.

31 Aug 2021

Severe COVID-19 negatively impacts kidney function in kidney transplant recipients

During her medical school career, third-year student Skylar Nahi has taken advantage of the mentorship and research opportunities available to Feinberg students.

31 Aug 2021

Rescue breathing CPR for pediatric cardiac arrest has superior outcomes, analysis shows

Rescue breathing cardiopulmonary resuscitation (CPR) had superior neurological outcomes compared with compression-only CPR or no CPR at all in infants, children and adolescents, according to a new analysis published today in the Journal of the American College of Cardiology.

30 Aug 2021

New ESC/EACTS guidelines for the management of valvular heart disease published

The European Society of Cardiology (ESC) and European Association for Cardio-Thoracic Surgery Guidelines for the management of valvular heart disease are published online today in European Heart Journal.

28 Aug 2021

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Oncotarget published "Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis" which reported that microscopic imaging, immunocytochemistry, wound healing assay, caspase-cleaved cytokeratin 18 CytoDeath ELISA assay, immunofluorescence labeling assays for apoptosis, hypoxia, Western Blotting, Tunnel assay, measurement of 5-HT secretion by carbon fiber amperometry assay, quantitative methylation-specific PCR, morphologic changes, cell viability, apoptosis activity and the expression levels of phospho-Akt1, Akt1, HIF-1α, PI3K, p21, CAIX, 5-HT, phospho-mTOR, and mTOR in xenografts derived from typical H727 and atypical H720 BC cell lines.

28 Aug 2021

Study opens up a new approach to incorporating MRI into multisite pancreatic clinical trials

Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) at Vanderbilt University Medical Center led a multisite study which has demonstrated that, when controlled and standardized, quantitative magnetic resonance imaging (MRI) of the pancreas is highly reproducible when using different MRI hardware and software at different geographic locations.

28 Aug 2021

Neurons in visual cortex of the brain change their responses over time, research reveals

New research from Washington University in St. Louis reveals that neurons in the visual cortex - the part of the brain that processes visual stimuli - change their responses to the same stimulus over time.

28 Aug 2021

Ultrasound-based technology for measuring brain pressure could replace surgery

A new invention may be on the verge of replacing a costly cranial surgical procedure currently being performed on some traffic accident victims and other patient groups. The ultrasound-based technology has now been granted CE approval for the European market.

28 Aug 2021

Light-to-moderate coffee drinking linked to lower risk of stroke and fatal heart disease

Up to three cups of coffee per day is associated with a lower risk of stroke and fatal heart disease, according to research presented at ESC Congress 2021.

27 Aug 2021

Rapid blood test detects life-threatening placental disorder

Placenta accreta spectrum (PAS) disorder is a life-threatening condition that occurs when the placenta remains attached to the uterus after childbirth.

27 Aug 2021

Olympus Announces First Organoid Conference to Support Stem Cell Research

Olympus is proud to announce its first Olympus Organoid Conference—Think Deep, See Deeper, which will be held virtually on Sept. 7–9, 2021.

From Evident Corporation - Life Sciences 27 Aug 2021

Researchers convert human stem cells into beta cells using small molecules

The human body can be genetically inclined to attack its own cells, destroying the beta cells in the pancreas that make insulin, which helps convert sugar into energy.

27 Aug 2021

Study: Smell regulates our eating habits

Walking past a corner bakery, you may find yourself drawn in by the fresh smell of sweets wafting from the front door. You're not alone: The knowledge that humans make decisions based on their noses has led major brands like Cinnabon and Panera Bread to pump the scents of baked goods into their restaurants, leading to big spikes in sales.

27 Aug 2021

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.

26 Aug 2021

Imaging News and Research

Research investigates how drug-eluting stent affects arterial tissue permeability and blood flow

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

New AI technology for heart imaging could improve care for patients

Studies outlines novel strategies for detecting cancer and minimal residual disease

Blood test could enable early detection of cancer in people with neurofibromatosis type 1

$1.3 million in NIH funding to enable drug delivery technology research

Severe COVID-19 negatively impacts kidney function in kidney transplant recipients

Rescue breathing CPR for pediatric cardiac arrest has superior outcomes, analysis shows

New ESC/EACTS guidelines for the management of valvular heart disease published

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Study opens up a new approach to incorporating MRI into multisite pancreatic clinical trials

Neurons in visual cortex of the brain change their responses over time, research reveals

Ultrasound-based technology for measuring brain pressure could replace surgery

Light-to-moderate coffee drinking linked to lower risk of stroke and fatal heart disease

Rapid blood test detects life-threatening placental disorder

Olympus Announces First Organoid Conference to Support Stem Cell Research

Researchers convert human stem cells into beta cells using small molecules

Study: Smell regulates our eating habits

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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