Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Memory test offers clue to pathological diagnosis in primary progressive aphasia

Patients with primary progressive aphasia show selective vulnerabilities in effortless learning and delayed retrieval of verbal information if their syndrome is related to Alzheimer's disease rather than frontotemporal lobar degeneration, research indicates.

18 May 2016

First-ever clinical trial of bioabsorbable cardiovascular device in children shows promise

Current cardiovascular valve or blood vessel implants are generally associated with a number of complications, have limited efficacy over time, and may necessitate repeated interventions over a patient's lifetime, especially when implanted in a young child.

18 May 2016

Physical fitness may offer protection from Alzheimer's disease, other dementias

Recent research suggests that exercise might provide some measure of protection from Alzheimer's disease and other dementias.

17 May 2016

Researchers identify risk factors for unplanned readmissions following esophageal resection

Esophagectomy is a major surgical procedure associated with significant complications with up to 1 in 5 patients readmitted following hospital discharge. These unplanned readmissions are an important problem as they negatively impact patient care and, in the future, may have implications for reimbursement through the Hospital Readmissions Reduction program.

17 May 2016

High or rapidly rising BP poses greatest stroke, mortality risk

Findings from the Rotterdam study show how the trajectories of people's blood pressure in mid to late life have varying effects on their risk of having a stroke or dying.

17 May 2016

Many biomarkers for PD fail to inform on progression

Longitudinal monitoring of 30 tests for marker candidates in early Parkinson's disease has found that just 10 show significant changes commensurate with disease progression.

17 May 2016

RDAVR system improves survival of patients with severe aortic stenosis

When replacing a defective aortic valve with a new one, restoring function is the first priority. However, variables such as durability, length of surgery, duration of heart stoppage, size of the surgical incision, postoperative pain, and complications are other important considerations.

17 May 2016

PENTAX Medical releases OPTIVISTA EPK-i7010 Video Processor for more accurate endoscopic in vivo diagnosis

PENTAX Medical launches a world first for endoscopy, the OPTIVISTA EPK-i7010 Video Processor, featuring both digital and optical enhancements, in the European, Middle Eastern & African (EMEA) markets.

From PENTAX Medical Company 17 May 2016

Carol Fabian inducted into KU Women's Hall of Fame for contributions to breast cancer research

Among the women inducted into the University of Kansas Hall of Fame on April 14, 2016, was Carol Fabian, MD. Fabian, a professor of medicine at the University of Kansas Medical Center and director of the Breast Cancer Prevention Center at The University of Kansas Cancer Center, is a nationally recognized oncologist and a pioneer in in the field of breast cancer research.

17 May 2016

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Eisai Co., Ltd. has announced that its U.S. subsidiary Eisai Inc. has received approval from the U.S. Food and Drug Administration (FDA) for an additional indication for Eisai's in-house developed novel anticancer agent Lenvima (lenvatinib mesylate) in combination with everolimus for the treatment of patients with advanced renal cell carcinoma following one prior anti-angiogenic therapy.

16 May 2016

Birmingham Women's Hospital leads the way in genomic diagnosis

Birmingham Women's Hospital (BWH) has adopted a radical new technology to make it easier to identify rare diseases by their genetic causes, leading to a faster and more accurate diagnosis for the patient. The technology being used to do this is called Sapientia™ and it is facilitating the reclassification of disease.

16 May 2016

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

With more than 36.9 million people infected globally, HIV continues to be a major public health issue. Those living with the virus are at an increased risk for other non-AIDS diseases, such as cardiovascular disease and cancer, and though it's not entirely clear why, this has been associated with inflammation and abnormal blood clotting.

13 May 2016

Tau pathology closely tracks brain function during early AD

Tau tangles may be a better indicator of cognitive changes during Alzheimer's disease progression than beta-amyloid deposition, researchers propose.

13 May 2016

Mouse models of Zika virus infection in pregnancy provide basis to develop vaccines, treatments

Two mouse models of Zika virus infection in pregnancy have been developed by a team of researchers at Washington University School of Medicine in St. Louis. In them, the virus migrated from the pregnant mouse's bloodstream into the placenta, where it multiplied, then spread into the fetal circulation and infected the brains of the developing pups.

12 May 2016

Scientists identify new hots pots of antibiotic resistance

Antibiotic-resistant bacteria most often are associated with hospitals and other health-care settings, but a new study indicates that chicken coops and sewage treatment plants also are hot spots of antibiotic resistance.

12 May 2016

Comprehensive genomic characterizations of ACC provide potentially better treatment options

An international team of scientists, including those at the Translational Genomic Research Institute (TGen), have discovered new avenues of potential treatments for a rare and deadly cancer known as Adrenocortical Carcinoma, or ACC.

11 May 2016

Griffith researchers closer to identifying cause of Chronic Fatigue Syndrome

New findings regarding the pathology of Chronic Fatigue Syndrome (CFS) are bringing Griffith University researchers closer to identifying the cause of this disabling illness.

11 May 2016

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Pathologic changes of the retina caused by diabetes is the leading cause of blindness in working adults. Diabetic retinopathy has no known cure, treatment options are inadequate, and prevention strategies offer limited protection. In the first of its kind, a report in The American Journal of Pathology describes a potential new intraocular treatment based on manipulating the renin angiotensin system (RAS) that both prevents and reverses some characteristics of diabetic retinopathy in a mouse model.

10 May 2016

Fast image registration technology patent granted in the US

microDimensions announced today that the United States Patent and Trademark Office has issued the US Patent 2015/0016703 A1 for its method for image registration of sections, in particular of histological sections. The patented technology enables fast and accurate alignment of whole slide and other large images up to the scanned resolution.

From microDimensions - Bramlage Scientific GmbH 10 May 2016

Study provides vital information regarding four diagnostic PD-L1 assays

A pre-competitive consortia of pharmaceutical companies, diagnostic companies, and academic associations, including the International Association for the Study of Lung Cancer, announced phase I results of the "BLUEPRINT PD-L1 IHC ASSAY COMPARISON PROJECT" at the Annual Meeting of the American Association for Cancer Research on April 19.

6 May 2016

Pathology News and Research

Further Reading

Memory test offers clue to pathological diagnosis in primary progressive aphasia

First-ever clinical trial of bioabsorbable cardiovascular device in children shows promise

Physical fitness may offer protection from Alzheimer's disease, other dementias

Researchers identify risk factors for unplanned readmissions following esophageal resection

High or rapidly rising BP poses greatest stroke, mortality risk

Many biomarkers for PD fail to inform on progression

RDAVR system improves survival of patients with severe aortic stenosis

PENTAX Medical releases OPTIVISTA EPK-i7010 Video Processor for more accurate endoscopic in vivo diagnosis

Carol Fabian inducted into KU Women's Hall of Fame for contributions to breast cancer research

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Birmingham Women's Hospital leads the way in genomic diagnosis

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

Tau pathology closely tracks brain function during early AD

Mouse models of Zika virus infection in pregnancy provide basis to develop vaccines, treatments

Scientists identify new hots pots of antibiotic resistance

Comprehensive genomic characterizations of ACC provide potentially better treatment options

Griffith researchers closer to identifying cause of Chronic Fatigue Syndrome

Potential new intraocular treatment based on RAS manipulation can prevent or reverse diabetic retinopathy

Fast image registration technology patent granted in the US

Study provides vital information regarding four diagnostic PD-L1 assays

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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