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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

SARS-CoV-2 RNA in serum associated with poor prognosis and high mortality

A new preprint indicates the direct correlation between the presence of detectable viral RNA loads in serum, and clinical severity and death.

21 Dec 2020

South Korean city shows SARS-CoV-2 clade shift from V to GH over time

A new paper from South Korea describes the evolving SARS-CoV-2 genome in a single city, that of Gwangju, in the southwestern region of this country.

21 Dec 2020

Detecting SARS-CoV-2 sequences in blood monocytes

A meeting with doctors from Wuhan presented a compelling observation to Professor Laura Manuelidis, MD, from the Yale Medical School early in 2020.

21 Dec 2020

Research may lead to better treatment and vaccines for Ebola, COVID-19

In the midst of a global pandemic with COVID-19, it's hard to appreciate how lucky those outside of Africa have been to avoid the deadly Ebola virus disease.

21 Dec 2020

FDA issues first emergency use authorization for second COVID-19 vaccine

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the second vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

21 Dec 2020

Researchers create new polymer to deliver DNA and RNA-based therapies for diseases

University of Minnesota Twin Cities researchers in the Department of Chemistry have created a new polymer to deliver DNA and RNA-based therapies for diseases.

21 Dec 2020

Study identifies biomarker gene signature that indicates potential liver toxicity

When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal studies.

18 Dec 2020

AOAC INTERNATIONAL issues Certificates of Validation for three test kits that detect SARS-CoV-2

AOAC INTERNATIONAL announced today that it has issued Certificates of Validation for three proprietary test kits that detect SARS-CoV-2, the causative agent of COVID-19 illness, on environmental surfaces.

18 Dec 2020

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

There is light at the end of the COVID-19 pandemic tunnel. Several vaccines against the SARS-CoV-2 virus that causes COVID-19 are now in clinical trials, with one -- developed by Pfizer/BioNTech -- already having been approved for emergency use in the United States.

18 Dec 2020

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

A new study describes the in vitro mechanism by which remdesivir kinetically inhibits the replication of the virus that causes COVID-19, SARS-CoV-2.

18 Dec 2020

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

A new paper that appeared as a preprint on the medRxiv* server in December 2020 describes a nucleic acid test validated on saliva samples.

18 Dec 2020

Cell atlas helps better understand the biology of tropical disease parasite

The first cell atlas of an important life stage of Schistosoma mansoni, a parasitic worm that poses a risk to hundreds of millions of people each year, has been developed by researchers at the Wellcome Sanger Institute and their collaborators.

18 Dec 2020

COVID-19 particles will remain infectious as temperature begins to drop

Winter is coming in the northern hemisphere and public health officials are asking how the seasonal shift will impact the spread of SARS-CoV-2, the virus that causes COVID-19?

18 Dec 2020

Supercomputer simulations lead to an important viral inhibitor discovery

University of New Hampshire researchers recently used Comet at the San Diego Supercomputer Center at UC San Diego and Stampede2 at the Texas Advanced Computing Center to identify new inhibitor binding/unbinding pathways in an RNA-based virus.

17 Dec 2020

MFCR awards new grants to support an emerging approach to cancer therapeutics

The Mark Foundation for Cancer Research has awarded five new grants in support of an important, emerging approach to cancer therapeutics.

17 Dec 2020

High presence of SARS-CoV-2 nucleic acid in PCR test can predict future symptomatic disease

A new study by researchers at the Karolinska University Hospital in Sweden shows that testing for the presence of SARS-CoV-2 nucleic acid can help in containing the virus spread. Detecting the presence of high amounts of SARS-CoV-2 nucleic acid predicts future symptomatic disease, they found.

17 Dec 2020

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers from the Washington University School of Medicine, United States of America, recently demonstrated that the SARS-CoV-2 surface proteins alone triggered innate cell activity and the interferon signaling pathway.

17 Dec 2020

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

REPROCELL launches personalized iPSC production service alongside new B2C website for “Personal iPS” customers

REPROCELL has announced that they will launch a new service to generate individual-specific induced pluripotent stem cell (iPSC) in January.

From REPROCELL 17 Dec 2020

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

SARS-CoV-2 has infected over 71.5 million people and claimed over 1.6 million lives globally since December 2019.

17 Dec 2020

RNA News and Research

Further Reading

SARS-CoV-2 RNA in serum associated with poor prognosis and high mortality

South Korean city shows SARS-CoV-2 clade shift from V to GH over time

Detecting SARS-CoV-2 sequences in blood monocytes

Research may lead to better treatment and vaccines for Ebola, COVID-19

FDA issues first emergency use authorization for second COVID-19 vaccine

Researchers create new polymer to deliver DNA and RNA-based therapies for diseases

Study identifies biomarker gene signature that indicates potential liver toxicity

AOAC INTERNATIONAL issues Certificates of Validation for three test kits that detect SARS-CoV-2

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

Cell atlas helps better understand the biology of tropical disease parasite

COVID-19 particles will remain infectious as temperature begins to drop

Supercomputer simulations lead to an important viral inhibitor discovery

MFCR awards new grants to support an emerging approach to cancer therapeutics

High presence of SARS-CoV-2 nucleic acid in PCR test can predict future symptomatic disease

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

REPROCELL launches personalized iPSC production service alongside new B2C website for “Personal iPS” customers

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

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