Therapeutics News and Research

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Scientists reverse HIV latency, take major scientific step toward curative therapies

Approximately 38 million people are infected with HIV worldwide, about 1.1 million people in the United States. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells.

22 Jan 2020

Collaboration reveals promising therapeutic strategy for osteoarthritis

Osteoarthritis affects 240 million people worldwide and is one of the most common causes of disability in both humans and animals.

22 Jan 2020

Horizon Discovery enters into licensing agreement with NGM for GS knockout CHO K1 cell line

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation for cell line engineering, today announced that it will license its gene-edited Glutamine Synthetase knockout Chinese Hamster Ovary K1 cell line to NGM Biopharmaceuticals, Inc..

From Revvity 22 Jan 2020

Enterprise Therapeutics publishes open access paper on novel approach to treat cystic fibrosis

Enterprise Therapeutics Ltd, a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of patients suffering with respiratory disease, today announced the publication of its first peer-reviewed paper.

21 Jan 2020

SITESEEKER to be used for Otsuka’s therapeutics discovery programs

PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER, in disease-relevant pathways nominated by Otsuka.

From PhoreMost 21 Jan 2020

Study uncovers anticancer potential of many non-oncology drugs

Drugs for diabetes, inflammation, alcoholism -- and even for treating arthritis in dogs -- can also kill cancer cells in the lab, according to a study by scientists at the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute.

20 Jan 2020

'Methylation clock' gene found to have functional role in aging of the eye

A lengthy-named gene called Elongation of Very Long Chain Fatty Acids Protein 2 or ELOVL2 is an established biomarker of age.

16 Jan 2020

Advanced BioMatrix acquires HyStem products for R&D market

Advanced BioMatrix has acquired the HyStem line of products from Lineage Cell Therapeutics – previously BioTime/ESI Bio/Glycosan.

16 Jan 2020

InDepth Pharmaceuticals to commercialize novel technique to predict kidney transplant success

InDepth Pharmaceuticals, founded by Deepak Nihalani, Ph.D., the SmartState Endowed Chair in Renal Disease Biomarkers at the Medical University of South Carolina, has taken a vital step toward commercializing an innovative diagnostic technique that could better predict kidney transplant success in patients with focal segmental glomerulosclerosis (FSGS), a kidney disease that often leads to end-stage renal failure.

14 Jan 2020

Study reveals how clotting protein and blood platelets promote immune evasion, tumor progression

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer.

14 Jan 2020

Study shows how treatment resistance develops in patients with bile duct cancer

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute shows how resistance to a promising targeted drug develops in patients with a rare, lethal cancer of the bile ducts called cholangiocarcinoma.

14 Jan 2020

Insilico, Pfizer to jointly explore novel data and AI system for potential therapeutic targets

Insilico Medicine is pleased to announce that it has entered into a research collaboration with Pfizer Inc. to utilize Insilico's machine learning technology and proprietary Pandomics Discovery Platform with the aim of identifying real-world evidence for potential therapeutic targets implicated in a variety of diseases.

14 Jan 2020

Mayo Clinic launches Clinical Data Analytics Platform to improve the health of patients

Mayo Clinic announced the Clinical Data Analytics Platform as the first venture under the Mayo Clinic Platform, a strategic initiative to improve health care through insights and knowledge derived from data.

14 Jan 2020

Horizon Discovery to offer novel base editing technology for clinical research

Horizon Discovery today announced that it will provide access to a novel base editing technology licensed from Rutgers for exclusive use in therapeutic, diagnostic and services applications.

From Revvity 14 Jan 2020

Blocking AHR receptor can reverse obesity, study finds

Obesity, a global epidemic, is a known contributor to several cancers, including breast, colon, and pancreatic. Stopping the obesity epidemic could be a critical aid in preventing and treating numerous cancers. Researchers with the laboratory of Craig Tomlinson, PhD, at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center have found a critical target in this cause.

13 Jan 2020

Researchers identify new pathway as biological target for colon cancer

Researchers have found a way to help make chemotherapy more effective in treating colon cancer. They identified a new pathway (RICTOR/mTORC2) as a biological target for the disease.

13 Jan 2020

The Riney Family Multiple Myeloma Initiative to be established at Dana-Farber

Dana-Farber Cancer Institute will establish the Riney Family Multiple Myeloma Initiative to help improve outcomes and accelerate understanding of the underlying biology for the most challenging types of myelomas, cancers that form in a type of white blood cell called a plasma cell.

13 Jan 2020

Therapeutics News and Research

Scientists reverse HIV latency, take major scientific step toward curative therapies

Collaboration reveals promising therapeutic strategy for osteoarthritis

Horizon Discovery enters into licensing agreement with NGM for GS knockout CHO K1 cell line

Enterprise Therapeutics publishes open access paper on novel approach to treat cystic fibrosis

SITESEEKER to be used for Otsuka’s therapeutics discovery programs

Study uncovers anticancer potential of many non-oncology drugs

'Methylation clock' gene found to have functional role in aging of the eye

Advanced BioMatrix acquires HyStem products for R&D market

InDepth Pharmaceuticals to commercialize novel technique to predict kidney transplant success

Study reveals how clotting protein and blood platelets promote immune evasion, tumor progression

Study shows how treatment resistance develops in patients with bile duct cancer

Insilico, Pfizer to jointly explore novel data and AI system for potential therapeutic targets

Mayo Clinic launches Clinical Data Analytics Platform to improve the health of patients

Horizon Discovery to offer novel base editing technology for clinical research

Blocking AHR receptor can reverse obesity, study finds

Researchers identify new pathway as biological target for colon cancer

The Riney Family Multiple Myeloma Initiative to be established at Dana-Farber

A protein found in ovarian cancer may contribute to neurodegeneration in Alzheimer's disease

Researchers discover how a new immune system works to protect bacteria from phages

Scientists discover how bacterial evolution of antibiotic arsenals is providing new drug blueprints

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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