Aging News and Research

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Oral molecule prevents kidney stones and restores survival in mice

Scientists at the Buck Institute for Research on Aging have shown that an orally administered small molecule, N-propargylglycine (N-PPG), can completely prevent the formation of calcium oxalate kidney stones, protect against kidney failure, and fully restore normal survival in a mouse model of Primary Hyperoxaluria Type 2 (PH2), a rare and currently untreatable genetic disorder that causes progressive kidney failure in infants and young adults.

2 Apr 2026

Study reveals dual trends in gallbladder cancer burden worldwide

Announcing a new article publication in BIO Integration. Gallbladder and biliary tract cancers (GBTCs) are highly lethal malignancies with a heterogeneous global burden.

2 Apr 2026

Moderate wine intake tied to slower biological aging in men

Researchers studying 22,495 adults in Southern Italy found that men with moderate wine intake in the traditional Mediterranean diet range showed slightly slower biomarker-based biological aging, with the lowest estimated aging signal at about 170 mL per day. The study also found that overall ethanol intake did not show the same moderate-level pattern, and higher total alcohol intake was linked to faster biological aging in dose-response analyses.

2 Apr 2026

Rising climate pollution may double air quality alerts in the US

Research reveals climate-driven pollution will surge, increasing air quality alerts and highlighting the need for protective actions, especially for seniors.

2 Apr 2026

AEGIS tool helps scientists study evolution of aging and lifespan

Why do some species live for only weeks while others survive for centuries? Researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena have developed AEGIS, a freely available software tool that enables scientists to simulate evolution on a standard computer and investigate how lifespan and aging evolve under different ecological pressures and genetic constraints.

1 Apr 2026

Vitamin D levels in midlife tied to lower dementia risk marker

Having higher levels of vitamin D in the blood in middle age is associated with lower levels of tau protein in the brain, which is a sign of dementia, years later, according to a study published April 1, 2026, in Neurology Open Access, an official journal of the American Academy of Neurology.

1 Apr 2026

NIH funds major study on brain aging in Hispanic-Latino communities

The National Institutes of Health (NIH) has awarded UC Davis Health a $15.85 million grant to support the next phase of one of the nation's most extensive studies on brain aging in Hispanic-Latino communities.

1 Apr 2026

Popular vitamin B3 supplements could weaken cancer therapy effectiveness

Millions of Americans take daily supplements-nicotinamide mononucleotide (NMN), nicotinamide riboside (NR) and nicotinamide (NAM)-to boost energy, slow aging and protect the heart and brain.

1 Apr 2026

Gut microbiome changes improve memory in early cognitive decline

Research shows that modifying the gut microbiome can enhance cognitive performance and mitigate dementia risk, highlighting the gut-brain connection.

1 Apr 2026

Aging reshapes breast tissue creating environment favorable for cancer

Scientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age – including dramatic changes during menopause.

31 Mar 2026

Impaired lipid transport protein locks stressed cells into cellular limbo

When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as replicative senescence, cells remain alive but no longer proliferate.

31 Mar 2026

Plant-focused diets may decelerate epigenetic aging processes

A new research paper was published in Volume 18 of Aging-US on March 20, 2026, titled "Plant-based dietary patterns are associated with slower epigenetic aging."

31 Mar 2026

How swapping unhealthy foods can significantly reduce your heart risk

More than half of adults and about 60% of children in the U.S. have unhealthy diets, which can contribute to higher rates of health factors such as high blood pressure and obesity, and lead directly to poor health outcomes including deaths from cardiovascular disease and other chronic conditions, according to the American Heart Association.

31 Mar 2026

DNASE1L2 identified as a dynamic biomarker for TB progression

Tuberculosis (TB) remains one of the world's most serious public health threats, with approximately one-quarter of the global population infected with Mycobacterium tuberculosis. While most infections remain latent (LTBI), individuals with LTBI are at risk of progressing to active TB and potentially becoming new sources of transmission.

31 Mar 2026

How gut imbalance may drive obesity, diabetes, and heart disease

A new review argues that gut dysbiosis is closely linked to metabolic dysfunction through intertwined effects on inflammation, oxidative stress, gut barrier integrity, microbial metabolites, and epigenetic regulation. It also highlights microbiome-targeted strategies such as high-fiber diets, probiotics, prebiotics, postbiotics, exercise, and fecal microbiota transplantation as promising ways to support metabolic health.

30 Mar 2026