Research News and Research

RSS

Single dose of J&J's Ad26.COV2.S vaccine effective against SARS-CoV-2 including in South Africa variant

One of these vaccines, the Ad26.COV2.S vaccine by Johnson & Johnson and Janssen, is a recombinant, replication-incompetent human adenovirus type 26 vector that encodes full-length SARS-CoV-2 spike protein in a prefusion-stabilized conformation.

26 Apr 2021

Using estrogen to target drug-resistant breast cancer in mice

Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it.

26 Apr 2021

Real-world study in India finds COVISHIELD vaccine safe and effective

New research led by Naresh Trehan of Medanta-The Medicity in India found the COVISHIELD (ChAdOx1 nCoV-19 Corona Virus Vaccine) vaccine produced an immune response from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) two weeks after vaccination with limited side effects.

26 Apr 2021

SARS-CoV-2 limits type I and type III IFN protein biogenesis

New research led by Roy Parker of the University of Colorado Boulder finds that SARS-CoV-2 prevents the IFN response despite an increased presence of IFN-encoding mRNAs by suppressing transcriptional processes. Inhibition of IFN mRNAs triggers degradation from the activation of RNase L and the SARS-CoV-2 protein Nsp1.

26 Apr 2021

Study: ICD patients should be regularly screened for anxiety and depression

Patients receiving an implantable cardioverter defibrillator (ICD) should be regularly screened for anxiety and depression, according to research presented at EHRA 2021, an online scientific congress of the European Society of Cardiology (ESC)

26 Apr 2021

Foot assessments can help detect atrial fibrillation in patients with diabetes

Atrial fibrillation can be detected during annual foot assessments in patients with diabetes, according to research presented today at EHRA 2021, an online scientific congress of the European Society of Cardiology (ESC).

26 Apr 2021

Recombinant protein vaccine fails expectations for SARS-CoV-2 neutralization

New interim results of a phase 1-2 clinical trial published in The Lancet Infectious Diseases tested the safety and effectiveness of an adjuvanted recombinant protein vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) called CoV2 preS dTM.

26 Apr 2021

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

Lung cancer is a major global cause of mortality, reportedly accounting for 1.7 million deaths each year. The most common form of lung cancer is non-small-cell lung cancer (NSCLC), and early-stage NSCLCs can often be surgically resected.

26 Apr 2021

Researchers harness the body's own ability to block pain

Fentanyl, oxycodone, morphine--these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.

26 Apr 2021

Study examines smoking behavior after the implementation of California law

Smoking is the leading cause of preventable death in America and causes about 30% of all cancer deaths. That's why researchers with the UC Davis Comprehensive Cancer Center wanted to study the impact of a California law passed in 2016 that raised the tobacco sales age from 18 to 21.

26 Apr 2021

Study to evaluate how people with immune system deficiencies respond to COVID-19 vaccination

A study assessing how people with immune system deficiencies or dysregulations respond to COVID-19 vaccination has begun enrolling participants at the National Institutes of Health Clinical Center in Bethesda, Maryland.

26 Apr 2021

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

In their review paper recently published in the Indian Journal of Clinical Biochemistry, a group of authors discusses currently available and forthcoming CRISPR-based diagnostic assays, as well as the possibility of using the CRISPR/Cas system as a salient treatment or prevention strategy in the fight against coronavirus disease 2019 (COVID-19).

25 Apr 2021

Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors

A new multidisciplinary study from Australia, published in the open-access journal mBio, shows that three compounds used to treat cystic fibrosis, dry eye, and a specific medical dye may lead to future strategies for the treatment of coronavirus disease (COVID-19).

25 Apr 2021

Single dose of Pfizer-BioNTech COVID-19 vaccine induces immunity in CML patients

Researchers in the UK have shown that a single dose of the Pfizer-BioNTech vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induced antibody and cellular responses in patients with chronic myeloid leukemia (CML) who were taking tyrosine kinase inhibitors.

25 Apr 2021

Research News and Research

Single dose of J&J's Ad26.COV2.S vaccine effective against SARS-CoV-2 including in South Africa variant

Using estrogen to target drug-resistant breast cancer in mice

Real-world study in India finds COVISHIELD vaccine safe and effective

SARS-CoV-2 limits type I and type III IFN protein biogenesis

Study: ICD patients should be regularly screened for anxiety and depression

Foot assessments can help detect atrial fibrillation in patients with diabetes

Recombinant protein vaccine fails expectations for SARS-CoV-2 neutralization

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

Researchers harness the body's own ability to block pain

Study examines smoking behavior after the implementation of California law

Study to evaluate how people with immune system deficiencies respond to COVID-19 vaccination

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

Two repurposed drugs and a blue dye show potential as SARS-CoV-2 entry inhibitors

Single dose of Pfizer-BioNTech COVID-19 vaccine induces immunity in CML patients

Pfizer-BioNTech COVID-19 vaccine shows real-world efficacy, despite the circulation of B.1.1.7 variant

Scientists decode activation mechanism of SHP2 protein that can trigger cancer

Study sheds light on the ability of CBD to reduce pain

NIAID establishes a clinical research network to improve understanding of childhood asthma

Research could inform therapeutic approaches to ameliorate the effects of fetal immobility

Study characterizes anti-inflammatory effect of strawberry geranium on the skin

A guide to advancing biotherapeutic research eBook

Latest eBooks

Industry Focus eBook - Life Science Microscopy (2nd Edition)

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance