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Higher dose and shorter treatment of key antibiotic proven to be safe for TB patients

A higher dose and shorter treatment time of a cornerstone tuberculosis (TB) drug has proven to be safe for patients, according to a clinical trial led by researchers at St George's, University of London and results published in NEJM Evidence.

29 Aug 2023

Modern blood thinners linked to reduced risk of bleeding

Modern blood-thinning drugs (known as NOACs) reduce the risk of serious bleeding by up to 45 percent compared to the traditional drug Waran in the treatment of blood clots in the legs and lungs.

29 Aug 2023

Drug-encapsulated nanogels show potential for treating obesity and other liver diseases

A University of Massachusetts Amherst biomedical engineer has used a nanogel-based carrier designed in his lab to deliver a drug exclusively to the liver of obese mice, effectively reversing their diet-induced disease.

29 Aug 2023

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

Though drug developers have achieved some progress in treating Alzheimer's disease with medicines that reduce amyloid-beta protein, other problems of the disease including inflammation, continue unchecked.

29 Aug 2023

TBI-on-a-chip model traces link between head trauma and Alzheimer's

How much time elapses between a blow to the head and the start of damage associated with Alzheimer's disease?

29 Aug 2023

Inorganic nitrate reduces contrast-induced nephropathy in high-risk patients

Inorganic nitrate reduces contrast-induced nephropathy (CIN), improves renal outcomes and reduces cardiac events compared to placebo in patients at risk of renal injury undergoing coronary angiography for acute coronary syndrome, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

£5 million awarded to 12 projects aimed at tackling fatal drug overdoses

12 projects awarded a share of £5 million to reduce rates of fatal drug overdoses, as part of Vaccine Taskforce style approach to tackle health challenges.

29 Aug 2023

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Researchers explore the potential utility of ginger essential oil in preventing NASH.

29 Aug 2023

UC San Francisco scientists develop implantable bioreactor to treat kidney failure

Scientists at UC San Francisco are working on a new approach to treating kidney failure that could one day free people from needing dialysis or having to take harsh drugs to suppress their immune system after a transplant.

29 Aug 2023

Online test nails early Alzheimer's diagnosis with biomarker precision

Researchers have developed a novel digital cognitive testing platform, using the Oxford Cognitive Testing Portal, that correlates with serological biomarkers to accurately measure cognitive impairment in Alzheimer's patients. The study highlights the platform's effectiveness in capturing subtle signs of impairment, potentially revolutionizing early diagnosis and tracking of Alzheimer's disease.

28 Aug 2023

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

University of Michigan researchers have discovered that the same cellular mechanism involved in a form of cystic fibrosis is also implicated in a form of a rare disease called cystinosis.

28 Aug 2023

Experts warn of unintended consequences of using GLP-1RAs to treat childhood obesity

A team of clinicians, exercise scientists, pharmaceutical scholars, ethicists and behavioral experts at the University of California, Irvine, outlined their concerns that the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) to treat childhood obesity and type 2 diabetes may have unintended and adverse consequences for children's health.

28 Aug 2023

Scientific breakthrough could someday save the lives of children with rhabdomyosarcoma

"Every successful medicine has its origin story. And research like this is the soil from which new drugs are born," says Cold Spring Harbor Laboratory Professor Christopher Vakoc.

28 Aug 2023

First oral treatment for Lipoprotein(a) shows significant cholesterol reduction

A new drug offers a breakthrough world first treatment for Lipoprotein(a), a largely genetic form of cholesterol that increases the risk of heart attack and stroke, announced today by study lead Professor Stephen Nicholls, Director of the Monash University's Victorian Heart Institute and Victorian Heart Hospital.

28 Aug 2023

PROFID EHRA trial to assess the potential benefit of ICD therapy in myocardial infarction survivors

Is the routine implantation of an implantable cardioverter defibrillator (ICD) in myocardial infarction survivors with heart failure still an adequate therapy for prevention of sudden cardiac death?

28 Aug 2023

A review of the neurological imaging techniques in dementia diagnosis

Researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging.

28 Aug 2023

The past, present, and future of cancer drug development

A new editorial paper was published in Oncoscience (Volume 10) on August 17, 2023, entitled, "Cancer drug development yesterday, today and tomorrow."

25 Aug 2023

New guideline supports use of acetaminophen and NSAIDs for pediatric dental pain

Acetaminophen or non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are recommended as first-line treatments for managing short-term dental pain in children under age 12, according to a new clinical practice guideline developed by the American Dental Association Science & Research Institute (ADASRI), the University of Pittsburgh School of Dental Medicine and the Center for Integrative Global Oral Health at the University of Pennsylvania School of Dental Medicine.

25 Aug 2023

Vaccine-drug combination reduces life-threatening malaria cases and deaths in children

Giving young children the world's first malaria vaccine RTS,S/AS01E alongside antimalarial drugs before the rainy season has led to a significant reduction in life-threatening malaria cases and deaths for over five years, according to a landmark study.

25 Aug 2023

Pregaming culture on college campuses may be fueling alcohol and drug use

New research from Texas A&M University School of Public Health suggests that college students who "pregame," or participate in tailgating and similar activities before athletic events, are also more likely to take part in unsafe alcohol and other substance use.

25 Aug 2023

Drugs News and Research

Higher dose and shorter treatment of key antibiotic proven to be safe for TB patients

Modern blood thinners linked to reduced risk of bleeding

Drug-encapsulated nanogels show potential for treating obesity and other liver diseases

New drug candidate reduces inflammation and improves memory in Alzheimer's mouse models

TBI-on-a-chip model traces link between head trauma and Alzheimer's

Inorganic nitrate reduces contrast-induced nephropathy in high-risk patients

£5 million awarded to 12 projects aimed at tackling fatal drug overdoses

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

UC San Francisco scientists develop implantable bioreactor to treat kidney failure

Online test nails early Alzheimer's diagnosis with biomarker precision

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

Experts warn of unintended consequences of using GLP-1RAs to treat childhood obesity

Scientific breakthrough could someday save the lives of children with rhabdomyosarcoma

First oral treatment for Lipoprotein(a) shows significant cholesterol reduction

PROFID EHRA trial to assess the potential benefit of ICD therapy in myocardial infarction survivors

A review of the neurological imaging techniques in dementia diagnosis

The past, present, and future of cancer drug development

New guideline supports use of acetaminophen and NSAIDs for pediatric dental pain

Vaccine-drug combination reduces life-threatening malaria cases and deaths in children

Pregaming culture on college campuses may be fueling alcohol and drug use

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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