Efficacy News and Research

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Scientists identify a molecular regulator involved in resistance to breast cancer treatment

A team from the UNIGE has identified a potential target for restoring the efficacy of standard treatment in resistant patients.

10 Mar 2022

Novel nanoparticles enable synergy of radiation and photodynamic therapies of deep tumor tissues

Researchers Dr Yansong Feng and Prof. Hong Zhang at the Van 't Hoff Institute for Molecular Sciences at the University of Amsterdam (UvA) have designed and synthesized novel multi-layered, multi-functional nanoparticles that enable a combination of radiotherapy and photodynamic therapy for deep cancer tissue.

10 Mar 2022

Cross-species infectivity of SARS-CoV-2 variants correlated with prevalence

New research discusses the role of mutations in the receptor-binding domain of the spike protein in the generation of antibody resistance and loss of vaccine efficacy.

10 Mar 2022

Study finds chimeric mRNA induces potent and broadly acting neutralizing antibodies against SARS-CoV-2 variants

Researchers explored strategies to develop an mRNA-based COVID-19 vaccine that could elicit safer and wider protection against SARS-CoV-2 variants of concern.

10 Mar 2022

Study isolated largest panel of β-CoV broadly neutralizing antibodies to date

Researchers isolated a large panel of broadly neutralizing antibodies from COVID-19 recovered-vaccinated donors.

10 Mar 2022

The trajectory of B-cell immunity six months after mRNA vaccination

Researchers assess SARS-CoV-2 antibodies in individuals vaccinated with a mRNA COVID-19 vaccine six months after receiving their second dose.

10 Mar 2022

UQ and Moderna partner to research and develop vaccines against global public health threats

The University of Queensland has been selected as one of the first launch institutions in the world to partner with biotechnology company Moderna to research and develop vaccines to tackle the world's greatest global public health threats.

9 Mar 2022

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

The new drug nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled phase 3 clinical trial published in the New England Journal of Medicine.

9 Mar 2022

Novel radioligand therapy shown to increase survival of metastatic prostate cancer patients

A novel prostate cancer treatment - 225Ac-PSMA-617 radioligand therapy - has been shown to increase the progression free survival (PFS) and overall survival (OS) of metastatic castration-resistant prostate cancer (mCRPC) patients, according to research published by The Journal of Nuclear Medicine.

9 Mar 2022

New antimicrobial technology for air filters can kill bacteria, fungi and viruses in seconds

Researchers at the University of Birmingham working in partnership with firms NitroPep Ltd and Pullman AC have developed new antimicrobial technology for air filters which can in seconds kill bacteria, fungi and viruses including SARS-CoV-2 - providing a potential solution to prevent the spread of airborne infections.

9 Mar 2022

IPD pooled analysis quantifies the underlying hematological response following malaria infection

A new malaria study using a very large analysis of pooled individual patient data (IPD) from more than 70,000 patients of all ages, has been published today in BMC Medicine.

9 Mar 2022

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

A new study provides an overview of the use of mathematical modeling to determine severe acute respiratory syndrome coronavirus 2 kinetics.

9 Mar 2022

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated that the lower expression of EXOSC2 human protein safeguards from clinical coronavirus disease 2019 (COVID-19). This protective effect was via the reduced EXOSC2 expression-associated suppression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication.

9 Mar 2022

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Leptomeningeal disease is a rare complication of several different types of cancer, including melanoma. It occurs when tumor cells migrate to the cerebrospinal fluid and the tissue that surrounds the brain and spinal column known as the meninges.

8 Mar 2022

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

A recent study predicted the efficacy of the SOBERANA 02 and SOBERANA Plus COVID-19 vaccines in children.

8 Mar 2022

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Researchers presented a technique called rapid in vitro inhibition assay (RIVIA), whereby potential SARS-CoV-2 antibody and nanobody candidates can be rapidly screened.

8 Mar 2022

Scientists predict structure of SARS-CoV-2 frameshifting pseudoknot

Researchers recently unveiled the structure of programmed -1 ribosomal frameshifting pseudoknot of SARS-CoV-2.

8 Mar 2022

Study shows anti-itch and pain relief potential of protein in tick saliva

A protein found in tick saliva could be turned into a drug that eases itching and chronic pain in people.

8 Mar 2022

SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

In a recent study posted to the medRxiv* preprint server, researchers investigated the efficacy of diagnostic tests for identifying severe acute respiratory syndrome coronavirus (SARS-CoV-2) variants of concern (VOCs).

8 Mar 2022

French study shows COVID vaccine efficacy 94% against severe outcomes

A recent paper published on the medRxiv preprint server utilized data from three national databases containing an abundance of information on Covid-19 screening (SI-DEP), vaccination (VAC-SI), and hospitalizations (SI-VIC) in France to provide additional perspectives on vaccine effectiveness and its evolution over the year 2021 in the French context.

7 Mar 2022

Efficacy News and Research

Scientists identify a molecular regulator involved in resistance to breast cancer treatment

Novel nanoparticles enable synergy of radiation and photodynamic therapies of deep tumor tissues

Cross-species infectivity of SARS-CoV-2 variants correlated with prevalence

Study finds chimeric mRNA induces potent and broadly acting neutralizing antibodies against SARS-CoV-2 variants

Study isolated largest panel of β-CoV broadly neutralizing antibodies to date

The trajectory of B-cell immunity six months after mRNA vaccination

UQ and Moderna partner to research and develop vaccines against global public health threats

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

Novel radioligand therapy shown to increase survival of metastatic prostate cancer patients

New antimicrobial technology for air filters can kill bacteria, fungi and viruses in seconds

IPD pooled analysis quantifies the underlying hematological response following malaria infection

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

Lower exosome component 2 expression protects against clinical SARS-CoV-2 infection

Patient-derived circulating tumor cells could be used to identify drug targets for leptomeningeal disease

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

Identification of a rapid test for SARS-CoV-2 neutralization via antibodies and nanobodies

Scientists predict structure of SARS-CoV-2 frameshifting pseudoknot

Study shows anti-itch and pain relief potential of protein in tick saliva

SARS-CoV-2 variant identification by RT-qPCR assays targeting mutations

French study shows COVID vaccine efficacy 94% against severe outcomes

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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