Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Series of routine tests may not be beneficial to patients with age-related disorder

A series of tests physicians routinely order to help diagnose and follow their patients with an elevated antibody level that is a marker for cancer risk, often do not benefit the patient but do increase health care costs, pathologists report.

27 Apr 2016

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Liver failure often occurs after an extensive hepatectomy, which is the surgical resection of the liver. While liver cell transplantation is a useful therapy for acute liver failure after massive hepatectomy, when cells are transplanted through liver portal veins raises the risk of embolization, such as the formation and movement of a blood clot, often with fatal consequences.

26 Apr 2016

Same genetic changes responsible for gastrointestinal problems in children with autism

Researchers at Columbia University Medical Center have found evidence in mice that, for some types of autism, gastrointestinal difficulties may originate from the same genetic changes that lead to the behavioral and social characteristics of the condition. The study was published in the Journal of Clinical Investigation.

26 Apr 2016

Exposure to blue light may lead to eyestrain but does not damage retina

Nearly 90 percent of adults use digital devices for two or more hours per day, according to The Vision Council's 2016 Digital Eye Strain Report, exposing consumers to blue light that some suggest is dangerous.

26 Apr 2016

Researchers describe how bed bugs break down insecticides

There are many reasons why bed bugs have made a comeback in recent decades, and their resistance to commonly used insecticides is one of the most widely accepted explanations.

22 Apr 2016

Open source machine learning tools as good as humans in detecting cancer cases

Machine learning has come of age in public health reporting according to researchers from the Regenstrief Institute and Indiana University School of Informatics and Computing at Indiana University-Purdue University Indianapolis.

22 Apr 2016

FAU's clinical trial to evaluate efficacy of RVT-101 tablet for Lewy body dementia

Florida Atlantic University's Charles E. Schmidt College of Medicine is spearheading the South Florida site for the first U.S. clinical trial for Lewy body dementia (LBD), the second-most common dementia after Alzheimer's disease. The HEADWAY-DLB is a phase 2b multi-center, double-blind, placebo-controlled study to evaluate an investigational medicine, RVT-101, for dementia with Lewy bodies.

22 Apr 2016

Infected mice can be better models for human diseases

Vaccines and therapeutics developed using mice often don't work as expected in humans. New research at Washington University School of Medicine in St. Louis points to the near-sterile surroundings of laboratory mice as a key reason.

21 Apr 2016

New study explores mechanisms that control size, shape of tubular organ systems

A new study from the group of Holger Gerhardt in collaboration with Katie Bentley's Lab addresses a long standing question in the wider field of developmental biology and tissue patterning in general, and in the vascular biology field in particular: 'What are the fundamental mechanisms controlling size and shape of tubular organ systems'.

21 Apr 2016

Better way to model human immune system

Scientists at the University of Minnesota have developed a new way to study mice that better mimics the immune system of adult humans and which could significantly improve ways to test potential therapeutics. Published online today in the journal Nature, the researchers describe the limitations of laboratory mice for immunology research and reveal the benefits of what they are calling "dirty mice."

21 Apr 2016

TNF-alpha protein involved in autoimmune diseases may also promote tissue healing

As its name suggests, inflammatory bowel disease, which afflicts more than 1.6 million Americans, involves chronic inflammation of all or some of the digestive tract. An autoimmune disease known to have a strong genetic component, its symptoms are abdominal cramps, bloody diarrhea, and fever and, sometimes, weight loss. IBD, which is a group of inflammatory conditions, includes Crohn's disease and ulcerative colitis.

21 Apr 2016

Scientists aim to identify marker that could indicate aggressive basal cell skin cancer

Most basal cell skin cancers are easily removed -- those on the arm, leg or back. But when the cancer is on the eyelid or when it starts to invade surrounding tissue, it's no longer straightforward.

21 Apr 2016

LAP defects may lead to lupus-like autoimmune disorder

A casual observation about size differences in mice has led to the discovery that defects in a process for digesting dead cells called LC3-associated phagocytosis (LAP) may lead to a lupus-like autoimmune disorder. St. Jude Children's Research Hospital scientists led the research, which appears as an advance online publication today in the scientific journal Nature.

21 Apr 2016

New mouse model to aid in development of antiviral compounds, vaccines against Zika virus

Researchers at the University of Wisconsin-Madison School of Veterinary Medicine have developed one of the first mouse models for the study of Zika virus. The model will allow researchers to better understand how the virus causes disease and aid in the development of antiviral compounds and vaccines.

20 Apr 2016

Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Antibiotic resistance is one of the most challenging problems in modern medicine. A new study by Erida Gjini and Patricia H. Brito from the Instituto Gulbenkian de Ciência, provides a new mathematical model to evaluate the best treatment protocol to clear an infection, by taking into account the role of the host immune system.

20 Apr 2016

Well-established optics technique can locate brain tumors within a minute compared to conventional methods

When operating on cancer, surgeons want to remove tumors and not healthy tissue. This is especially important and challenging when dealing with brain tumors, which are often spread out and mixed in with the healthy tissue. Now, researchers have shown that a well-established optics technique can reveal exactly where brain tumors are, producing images in less than a minute -- unlike conventional methods that can take a whole day.

19 Apr 2016

OASIS study to investigate link between SIDS and alteration on newborn hearing screen test

Seattle Children's is partnering on the launch of a study called the 'Oto-Acoustic Signals in SIDS'study that will investigate a possible association between Sudden Infant Death Syndrome (SIDS) and hearing alteration on the newborn hearing screen test.

19 Apr 2016

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

Cancer cells often devise ways to survive even in the presence of toxic chemotherapy. Now, a research team led by investigators at Beth Israel Deaconess Medical Center has found a way to attack a process that tumor cells use to escape the effects of standard cancer drugs. The discovery is published online today in the journal Nature Cell Biology.

19 Apr 2016

MR may detect earliest Alzheimer's brain changes

Levels of the brain metabolite and neuroinflammation marker myo-inositol are elevated in asymptomatic patients with abnormal Alzheimer's disease (AD) biomarkers, say researchers. As repo ...

18 Apr 2016

UA researchers developing new treatment to delay serious consequences of venomous snakebites

Time is of the essence for treating venomous snakebites, and a product being developed by researchers at the University of Arizona College of Medicine - Tucson may extend that window for treatment.

18 Apr 2016

Pathology News and Research

Further Reading

Series of routine tests may not be beneficial to patients with age-related disorder

Acute liver failure after massive hepatectomy improves with liver cell transplantation

Same genetic changes responsible for gastrointestinal problems in children with autism

Exposure to blue light may lead to eyestrain but does not damage retina

Researchers describe how bed bugs break down insecticides

Open source machine learning tools as good as humans in detecting cancer cases

FAU's clinical trial to evaluate efficacy of RVT-101 tablet for Lewy body dementia

Infected mice can be better models for human diseases

New study explores mechanisms that control size, shape of tubular organ systems

Better way to model human immune system

TNF-alpha protein involved in autoimmune diseases may also promote tissue healing

Scientists aim to identify marker that could indicate aggressive basal cell skin cancer

LAP defects may lead to lupus-like autoimmune disorder

New mouse model to aid in development of antiviral compounds, vaccines against Zika virus

Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Well-established optics technique can locate brain tumors within a minute compared to conventional methods

OASIS study to investigate link between SIDS and alteration on newborn hearing screen test

Researchers find way to attack a process that tumor cells use to escape effects of cancer drugs

MR may detect earliest Alzheimer's brain changes

UA researchers developing new treatment to delay serious consequences of venomous snakebites

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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