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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers explore whether cocoa supplementation can reduce aging

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Family's socio-economic status may influence children's composition of gut microbiome

Findings of a nationwide study led by the Translational Genomics Research Institute, an affiliate of City of Hope, suggest that a family's socio-economic status may influence children's composition of gut microbiome - the mix of microscopic organisms within the digestive tract.

14 Sep 2021

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

A synthetic molecular code shows promise towards improving the response of some cancer patients to immunotherapy treatments.

14 Sep 2021

Study compares DNA extraction and amplification methods used for microbiome research

Let's face it, we are a results-driven society. Too focused on the outcome, people don't often think about the "how." For instance, did you think about "how" you got to work this morning or did you just get there? In microbiome studies the results are the graphs and the data but the "how," like commuting, is often just part of a routine.

14 Sep 2021

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

A recent study examined the ability of SARS-CoV-2 to impact DNA damage response and telomere stability in Vero E6 cells.

13 Sep 2021

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

A recent study, currently available on the bioRxiv* preprint server, reveals that a specific region of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be targeted by antisense oligonucleotides to potently inhibit viral replication, and consequently the development of coronavirus disease (COVID-19).

12 Sep 2021

Neutrophil extracellular traps boost the bacterial killing power of macrophages

Like a spider trapping its prey, our immune system cells cooperate to capture and "eat" bacteria.

12 Sep 2021

Researchers discover transposon-encoded RNA-guided nucleases with potential for genome editing

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

12 Sep 2021

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

For men with "low-risk" prostate cancer initially managed with active surveillance, cancer-related factors such as tumor grade and size are key risk factors for conversion to active treatment, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association.

10 Sep 2021

Washington University School of Medicine receives $7 million to investigate how human genome works

Washington University School of Medicine in St. Louis has received a $7 million grant from the National Institutes of Health to help lead national efforts to investigate how variations in the human genome sequence affect how the genome functions.

9 Sep 2021

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

Sequencing the human genome - a feat accomplished in 2003 - provided the list of ingredients that make up a human being, but not the instructions that explain how those ingredients are used by each cell type to create complex "meals."

9 Sep 2021

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.

9 Sep 2021

IGVF consortium receives NIH funding to study how genomic variation influences biological function

The National Institutes of Health is providing approximately $185 million over five years to the Impact of Genomic Variation on Function consortium, initiated and funded by NIH's National Human Genome Research Institute.

9 Sep 2021

Are bat retroviruses a threat to humans?

Zoonotic viruses that bats transmit are capable of infecting humans and have caused devastating infections throughout the world.

9 Sep 2021

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Researchers in Australia have developed a coronavirus disease 2019 (COVID-9) vaccine that induced robust and long-lived humoral and cellular immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both young and aging mice.

8 Sep 2021

Self-correcting genetic mutations may protect patients with shortened telomeres from blood cancers

People with rare disorders that cause shortened telomeres — protective caps that sit at the end of chromosomes — may be more likely to have blood cancers such as leukemia or myelodyplastic syndrome.

8 Sep 2021

$New tool can rapidly quantify T cell fraction and predict immunotherapy response$

New tool can rapidly quantify T cell fraction and predict immunotherapy response

Scientists at UCL and the Francis Crick Institute, London, have developed a new tool, which can rapidly estimate the number of T cells (immune cells) in a cancerous tumor; with T cell abundance helping predict a patient's response to immunotherapy, researchers are hopeful this could enable more targeted and effective cancer therapies.

8 Sep 2021

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Despite cigarette smoking being the single most preventable risk factor for both chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), two devastating diseases that make it hard to breathe, about 44 million American adults continue to smoke.

8 Sep 2021

Asthmatic children who are overweight or obese less likely to respond to inhaled steroids

Asthmatic children are less likely to respond to inhaled steroid medication if they are overweight or obese, and this leads to more frequent asthma attacks, according to research presented at the 'virtual' European Respiratory Society International Congress today (Wednesday).

8 Sep 2021

DNA News and Research

Further Reading

Researchers explore whether cocoa supplementation can reduce aging

GIST researchers unravel coordination mechanism of base excision repair

Family's socio-economic status may influence children's composition of gut microbiome

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

Study compares DNA extraction and amplification methods used for microbiome research

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

Neutrophil extracellular traps boost the bacterial killing power of macrophages

Researchers discover transposon-encoded RNA-guided nucleases with potential for genome editing

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

Washington University School of Medicine receives $7 million to investigate how human genome works

UC San Diego researchers receive $6 million NIH grant to study insulin-producing cells

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

IGVF consortium receives NIH funding to study how genomic variation influences biological function

Are bat retroviruses a threat to humans?

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Self-correcting genetic mutations may protect patients with shortened telomeres from blood cancers

New tool can rapidly quantify T cell fraction and predict immunotherapy response

Researchers receive $12.8M renewal grant to reveal how smoking causes distinct lung diseases

Asthmatic children who are overweight or obese less likely to respond to inhaled steroids

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