Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Intestinal bacteria can be used to reduce cancer risk, reveals UCLA study

Researchers have shown that various types of intestinal bacteria might be factors in both causing and preventing obesity, and in other conditions and diseases. Now, a UCLA study suggests that it could also potentially be used to reduce the risk for some types of cancer.

16 Apr 2016

International panel reclassifies a type of thyroid tumor to reduce cancer overdiagnosis

Led by researchers at the University of Pittsburgh School of Medicine, an international panel of pathologists and clinicians has reclassified a type of thyroid cancer to reflect that it is noninvasive and has a low risk of recurrence. The name change, described today in JAMA Oncology, is expected to reduce the psychological and medical consequences of a cancer diagnosis, potentially affecting thousands of people worldwide.

16 Apr 2016

Alzheimer's preclinical staging criteria supported

The Alzheimer's disease preclinical staging criteria proposed by the National Institute on Aging and the Alzheimer's Association appear to be valid over more than a decade of follow-up, say researchers.

15 Apr 2016

Johns Hopkins study suggests updated universal screening for hepatitis C virus

A review of blood samples for nearly 5,000 patients seen at The Johns Hopkins Hospital Emergency Department suggests that federal guidelines for hepatitis C virus (HCV) screening may be missing up to a quarter of all cases and argues for updated universal screening.

15 Apr 2016

International scientists discuss new treatments for non small cell lung cancer

More than 30 prominent international scientists gathered to discuss the state-of-the-art, as well as promising future approaches for the treatment of lung cancer at the stunning 17th century Borgo San Luigi, in Monteriggion, in the heart of the Tuscany countryside.

13 Apr 2016

BMI Healthcare innovates in cancer services technology

Representing excellence and innovation in the field of healthcare, BMI Healthcare has been shortlisted as a finalist in the IT Innovator of the Year category of this year’s HealthInvestor Awards.

13 Apr 2016

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies

Accurate diagnosis of Parkinson's disease, and the related disease "dementia with Lewy bodies," can be difficult in the early stages of both conditions. While brain biopsies can be more accurate, the risk of complications has been considered too high. New research published in the Journal of Parkinson's Disease indicates that a biopsy of the submandibular gland can help identify the same pathology that is seen in the brain, providing some of the increased accuracy of brain biopsy, but not the increased risk.

12 Apr 2016

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune disease, said researchers at Penn State College of Medicine.

12 Apr 2016

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

In a new study, researchers from Columbia University Medical Center described a new mouse model featuring a combination of genetic and environmental risk factors that can trigger the compulsive restriction of food intake seen in patients with anorexia nervosa. The findings may help to identify new prevention and treatment strategies for the eating disorder in humans.

12 Apr 2016

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Sepsis represents a serious complication of infection and is one of the leading causes of death and critical illness worldwide due in part to the lack of effective therapies. A report in the American Journal of Pathology provides evidence from both mouse and human studies that SHARPIN, a protein involved in regulating inflammation, has anti-septic effects. These findings may spur development of novel sepsis treatments.

11 Apr 2016

Genetically modified pig hearts can survive for more than 2 years after transplantation into baboons

Could organs explanted from other mammals save human lives someday? A new study shows that genetically modified pig hearts developed by US and Ludwig-Maximilians-Universitaet in Munich researchers can survive for more than up to 2½ years when transplanted into baboons.

7 Apr 2016

Radiation therapy plus PCV chemotherapy improves survival of low-grade glioma patients

Patients with a low-grade type of brain tumor called glioma who received radiation therapy plus a chemotherapy regimen, including procarbazine, lomustine and vincristine (PCV), experienced a longer progression-free survival and overall survival than patients who received radiation therapy alone, according to the results of the clinical trial, Radiation Therapy Oncology Group 9802 published in the April 7 issue of the New England Journal of Medicine.

7 Apr 2016

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Advances in technology allow scientists to measure intricate details about the human body that greatly enhance understanding of health, disease and aging.

7 Apr 2016

Researchers develop mouse model for testing vaccines, therapeutics to battle Zika virus

A research team at Washington University School of Medicine in St. Louis has established a mouse model for testing of vaccines and therapeutics to battle Zika virus.

6 Apr 2016

Study shows how Down Syndrome gene associated with altered oscillations in the cerebral cortex

Cerebral activity is governed by a fine balance between neuronal excitation and inhibition. Specifically, neurons are activated by excitation mechanisms tightly regulated by inhibition processes. For certain functions, the neuronal network needs to be synchronized.

6 Apr 2016

Researchers identify possible genetic basis for coronary artery disease

For many people, coronary artery disease, or CAD—the buildup of plaque in the heart's arteries—is an unfortunate part of aging. By studying the genetic makeup of those who manage to maintain clear arteries into old age, researchers have identified a possible genetic basis for the disease, as well as potential new opportunities to prevent it.

6 Apr 2016

Biopsy detects αSyn in submandibular gland of IRBD patients

Submandibular gland biopsy can be used to identify α-synuclein aggregates, potentially offering not only a simple means of histologically confirming Parkinson's disease but also a marker for the disease in patients with premotor manifestations, researchers report.

5 Apr 2016

Study links effects of prenatal alcohol and drug exposure with placental development

In the United States, prenatal alcohol exposure (PAE) is the most common preventable cause of developmental delay. Animal studies have shown some of the adverse effects of PAE on placental development, but few studies have examined these effects in humans. This is the first study to examine the effects of prenatal exposure to methamphetamine, marijuana, and cigarette smoking on human placental development.

5 Apr 2016

Chronic lack of sleep, irregular sleep-wake cycles may increase risk of Parkinson's disease

Chronic lack of sleep and irregular sleep-wake cycles may be risk factors of Parkinson's disease, new work by researchers at the Lewis Katz School of Medicine at Temple University suggests. In an animal model, the researchers show that disturbances in circadian rhythm that exist before Parkinson's onset dramatically worsen motor and learning deficits brought on by the disease.

5 Apr 2016

Combining aromatase inhibitors with growth hormone may help short adolescent boys grow taller

Aromatase inhibitors, when used for up to three years in combination with growth hormone, may effectively and safely help very short adolescent boys grow taller, new research suggests. The study results will be presented Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society in Boston.

4 Apr 2016

Pathology News and Research

Further Reading

Intestinal bacteria can be used to reduce cancer risk, reveals UCLA study

International panel reclassifies a type of thyroid tumor to reduce cancer overdiagnosis

Alzheimer's preclinical staging criteria supported

Johns Hopkins study suggests updated universal screening for hepatitis C virus

International scientists discuss new treatments for non small cell lung cancer

BMI Healthcare innovates in cancer services technology

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

Researchers find evidence that protein involved in regulating inflammation has anti-septic effects

Genetically modified pig hearts can survive for more than 2 years after transplantation into baboons

Radiation therapy plus PCV chemotherapy improves survival of low-grade glioma patients

Person's age, mobility could be powerful predictors of survival than certain biomarkers

Researchers develop mouse model for testing vaccines, therapeutics to battle Zika virus

Study shows how Down Syndrome gene associated with altered oscillations in the cerebral cortex

Researchers identify possible genetic basis for coronary artery disease

Biopsy detects αSyn in submandibular gland of IRBD patients

Study links effects of prenatal alcohol and drug exposure with placental development

Chronic lack of sleep, irregular sleep-wake cycles may increase risk of Parkinson's disease

Combining aromatase inhibitors with growth hormone may help short adolescent boys grow taller

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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