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New diagnostic test detects and identifies SARS-CoV-2 virus in less than five minutes

Scientists from Oxford University’s Department of Physics have developed an extremely rapid diagnostic test that detects and identifies viruses in less than five minutes.

16 Oct 2020

'Jumping genes' may frequently alter neural function

A new study by neuroscientists at the University of Oxford shows that mobile genetic elements that were active in the genomes of our ancestors could be closely linked to important functions in our brain and might help diversify our behavior, cognition and emotions.

16 Oct 2020

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Synthego, the genome engineering company, has collaborated with The Krogan Lab, a world-renowned scientific research unit at the Quantitative Biosciences Institute (QBI) at the University of California, San Francisco (UCSF), to deliver multiple CRISPR-based engineered cell lines to accelerate the study of potential treatment targets for SARS-CoV-2, the novel coronavirus that causes COVID-19 disease.

16 Oct 2020

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Why are some people more resilient to viruses than others? The answer has eluded scientists for centuries and, in the age of COVID-19, has come to represent one of the holy grails of biomedical research.

16 Oct 2020

Early trauma leads to changes in blood metabolites, study finds

A study by the Brain Research Institute at UZH reveals that early trauma leads to changes in blood metabolites - similarly in mice and humans.

15 Oct 2020

NIH grants 4D Nucleome award to support research by Gladstone scientists

The National Institutes of Health has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, PhD, and Katie Pollard, PhD.

15 Oct 2020

Mendelian randomization helps evaluate impact of circulating proteins in COVID-19

Researchers identify circulating proteins influencing COVID-19 susceptibility and severity by employing a large-scale two-sample Mendelian randomization (MR) study.

15 Oct 2020

Study links SARS-CoV-2 seasonality to increased spread at lower temperatures

In a recent paper available on the bioRxiv preprint server, US researchers show that individual particles of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) undergo structural destabilization at relatively mild but elevated temperatures – strengthening the case for coronavirus disease (COVID-19) resurgence in the winter.

15 Oct 2020

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

A large international consortium of almost 200 researchers from 14 leading institutions in six countries has studied three different coronaviruses - SARS-CoV-1, SARS-CoV-2, and MERS-CoV - with the aim of finding vulnerabilities shared by these three pathogens.

15 Oct 2020

Cloud-based tool can rapidly detect and track emerging pathogens

Published today in the journal GigaScience is a new open source, cloud-based tool called IDseq that makes it possible to rapidly detect, identify, and track emerging pathogens such as SARS-CoV-2.

15 Oct 2020

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumors. The findings revealed possible approaches for developing precision medicines to improve patient outcomes. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Nature Communications.

15 Oct 2020

Study shows how HGT can bend the rules of evolution

In a world first Monash University scientists have discovered that HGT can bend the rules of evolution. The discovery is outlined in a study published today in PNAS, which was led by ARC Future Fellow Dr Mike McDonald and PhD candidate Laura Woods, both from the Monash University School of Biological Sciences.

15 Oct 2020

G protein-coupled receptors help humans taste, smell, and regulate mood and immunity

Dr. Guangyu Wu is dissecting the molecular homing that enables a nascent protein to ultimately find its way to the surface of a cell as a mature receptor type that helps us taste, smell and even regulate our mood and immunity.

14 Oct 2020

Alternate primers for whole-genome SARS-CoV-2 sequencing

A new study published on the preprint server bioRxiv* in October 2020 describes the gap frequencies and positions in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and a set of alternative primers with a sequencing scheme to provide better genomic coverage and quality.

14 Oct 2020

Modification of DNA structure plays key role in the recovery phase after DNA damage

A research team from Cologne has discovered that a change in the DNA structure - more precisely in the chromatin - plays a decisive role in the recovery phase after DNA damage.

14 Oct 2020

EuCanImage to build scalable cancer imaging platform for next-generation artificial intelligence in oncology

EuCanImage has been launched. This project from the Horizon 2020 program is coordinated by Karim Lekadir, Ramón y Cajal postdoctoral researcher at the Faculty of Mathematics and Computer Science.

13 Oct 2020

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection.

12 Oct 2020

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Peer reviewers flag misleading studies on COVID-19

The preprints selected for review in Rapid Reviews: COVID-19 (RR:C19), an open-access overlay journal published by the MIT Press, cover a wide range of subjects, with peer reviewers finding a study that higher levels of cytokines IL-6 and IL-10 are associated with increased severity of COVID-19 is particularly noteworthy and could be useful in clinical care.

12 Oct 2020

Genome News and Research

New diagnostic test detects and identifies SARS-CoV-2 virus in less than five minutes

'Jumping genes' may frequently alter neural function

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Early trauma leads to changes in blood metabolites, study finds

NIH grants 4D Nucleome award to support research by Gladstone scientists

Mendelian randomization helps evaluate impact of circulating proteins in COVID-19

Study links SARS-CoV-2 seasonality to increased spread at lower temperatures

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

Cloud-based tool can rapidly detect and track emerging pathogens

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Study shows how HGT can bend the rules of evolution

G protein-coupled receptors help humans taste, smell, and regulate mood and immunity

Alternate primers for whole-genome SARS-CoV-2 sequencing

Modification of DNA structure plays key role in the recovery phase after DNA damage

EuCanImage to build scalable cancer imaging platform for next-generation artificial intelligence in oncology

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Peer reviewers flag misleading studies on COVID-19

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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