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Exploring the link between macular degeneration and retinitis pigmentosa

Four words you never want to hear from the eye doctor are retinitis pigmentosa and macular degeneration.

25 Nov 2019

Opioid use during pregnancy alters the baby's brain

During pregnancy, everything taken in by the mother crosses the placenta. Opioid use during pregnancy is tied to changes in the baby’s brain, a new study found.

25 Nov 2019

FDA-approved drug to prevent organ rejection may slow skin aging

The search for youthfulness typically turns to lotions, supplements, serums and diets, but there may soon be a new option joining the fray.

25 Nov 2019

Research yields potent antimicrobial that works against staph infection

Research led by scientists from McMaster University has yielded a potent antimicrobial that works against the toughest infectious disease strains. The find could be the beginning of developing new therapeutics to combat drug-resistant infections.

25 Nov 2019

New partnership aims to explore, cultivate innovations in cell and gene therapy

Some patients who have not responded to traditional medicines are now experiencing remarkable recoveries thanks to next-generation immunotherapies. These therapies equip a patient's own immune cells to recognize, target, and destroy cancer cells.

25 Nov 2019

Secretome of pleural effusions linked to NSCLC and malignant mesothelioma

Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system.

25 Nov 2019

Study shows how drinking patterns reprogram circadian metabolism in the liver

Drinking alcohol is a widespread habit in modern society and can have serious metabolic consequences. Recent studies have uncovered the interplay between nutrition, metabolism and circadian rhythms. But, until now, little has been done to understand the effects of alcohol consumption on circadian metabolism.

22 Nov 2019

Combination therapy improves survival in patients with hepatocellular carcinoma

Combination therapy with the PD-L1 inhibitor atezolizumab and the VEGF inhibitor bevacizumab significantly improves overall survival and progression-free survival in patients with unresectable hepatocellular carcinoma compared to standard of care, showed results from a phase 3 study reported at the ESMO Asia 2019 Congress.

22 Nov 2019

Researchers elucidate role of inflammation resolution sensor in obesity and heart failure

After heart attack injury, several fatty-acid-derived bioactive molecules -- including one called resolvin D1 -- play an essential signaling role to safely clear inflammation and help repair heart muscle. The mechanism of how this resolution occurs is not well-understood.

20 Nov 2019

BrainStorm publishes NurOwn ALS Phase 2 randomized clinical trial results in Neurology

BrainStorm Cell Therapeutics Inc., a leader in the development of innovative autologous cellular therapies for highly debilitating neurodegenerative diseases, today announced publication of "NurOwn Phase 2 Randomized Clinical Trial in ALS: Safety, Clinical and BioMarker Results," in the international, peer-reviewed journal Neurology.

20 Nov 2019

Breakthrough therapy could improve health and survival in people with cystic fibrosis

Researchers at the Children's Hospital Colorado Breathing Institute, one of the largest cystic fibrosis clinical care centers in the U.S., are part of a Therapeutics Development Network that oversaw clinical trials leading to FDA approval of TRIKAFTA, a new, highly-effective CF treatment for people with CF 12 years of age and older.

20 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

Cleveland Clinic receives NIH grant to study link between gut microbes, cardiometabolic diseases

The National Institutes of Health has awarded more than $12 million to Cleveland Clinic researchers to study the critical link between gut microbial pathways and the development of cardiometabolic diseases.

19 Nov 2019

Rutgers Cancer Institute researchers awarded $2.3 million in American Cancer Society grants

More than $2.3 million in Research Scholar Grants from the American Cancer Society have been awarded to three Rutgers Cancer Institute of New Jersey researchers to examine cell metabolism and tumor formation in forms of breast cancer, lung cancer and leukemia.

19 Nov 2019