Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Cause of amyloid beta pathology may be more versatile than previously known

Accumulation of the substance amyloid beta in the brain impairs the memory and cognitive ability in people with Alzheimer's. New findings from Lund University in Sweden show that the cause of amyloid beta pathology might be more versatile than previously known. Researchers believe that these new findings may be of significance to the development of new medications.

8 Mar 2016

Research provides important new insights into beginning stages of primary progressive aphasia

The recent ability to peer into the brain of living individuals with a rare type of language dementia, primary progressive aphasia (PPA), provides important new insights into the beginning stages of this disease -- which results in language loss -- when it is caused by a buildup of a toxic protein found in Alzheimer's disease.

8 Mar 2016

Specialized tests can help dermatologists provide individualized care for melanoma patients

Melanoma rates in the United States have doubled over the past two decades.1 Fortunately for patients, this increase in melanoma incidence has been accompanied by the development of more effective tools for diagnosis and treatment, including genetic and molecular testing.

7 Mar 2016

Complex biomarker tests for molecularly targeted therapies lack evidentiary standards

Potentially useful biomarker tests for molecularly targeted therapies are not being adopted appropriately into clinical practice because of a lack of common evidentiary standards necessary for regulatory, reimbursement, and treatment decisions.

7 Mar 2016

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

A study of obesity and related metabolic changes on bladder cancer incidence and deaths, and a plan to use stem cells to grow novel urinary tubes are among 10 research projects awarded funding by the Johns Hopkins Greenberg Bladder Cancer Institute.

7 Mar 2016

Kessler Foundation's Silvana L. Costa awarded Switzer Research Fellowship for research on MS

Silvana L. Costa, PhD, of Kessler Foundation has been awarded a Switzer Research Fellowship by the National Institute on Disability, Independent Living and Rehabilitation Research. The $70,000 Merit Award funds her research on "Processing Speed Deficits in Multiple Sclerosis: Exploring the Complex Sensorial Cognitive Motor Interaction."

7 Mar 2016

P53 genetic variant heavily implicated in metabolism, new research finds

The study may also provide an evolutionary explanation for differences in populations living farther away from the Equator. Human ancestors may have undergone this change in R72 to promote energy storage in cold climates and during times of famine. However, in modern society, the need for this type of variant in our genes is unnecessary, leading instead to increased risk for obesity and type 2 diabetes. Obesity is also a risk factor for certain types of cancer, so these findings may also explain why the R72 variant of p53 might predispose certain people to cancer.

4 Mar 2016

Study highlights new approach to produce coral snake antivenom from synthetically designed DNA

Coral snake venom carries significant neurotoxicity and human injuries can be severe or even lethal. Despite this, antivenom treatments are scarce due to challenges collecting adequate amounts of venom needed to produce anti-elapidic serum. PLOS Neglected Tropical Diseases highlights exciting new research from the Butantan Institute in Brazil using synthetically designed DNA to produce coral-snake antivenom.

4 Mar 2016

Cardiac reprogramming could shrink heart scar tissue, improve patients' heart function

Patients with heart failure often have a buildup of scar tissue that leads to a gradual loss of heart function. In a new study published today in the journal Cell Stem Cell, researchers from the University of North Carolina School of Medicine report significant progress toward a novel approach that could shrink the amount of heart scar tissue while replenishing the supply of healthy heart muscle.

4 Mar 2016

Steroid use in late preterm delivery can reduce rate of neonatal respiratory complications

Current recommendations are for all women who go into labor prior to 34 weeks gestation to be given antenatal corticosteroids (betamethasone) to help mature the baby's lungs. However, many babies born in the late preterm period - between 34 and 36 weeks gestation - require respiratory support at birth.

4 Mar 2016

Study provides critical insight into Warburg effect

PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. The findings may lay the groundwork for improved approaches to diagnosis and treatment of glioblastoma and other cancers.

4 Mar 2016

Researchers discover unexpected mechanism linked to aldosterone-induced heart damage

When the heart begins to fail, the body does everything in its power to fix the situation. But sometimes, those compensatory mechanisms ultimately do more harm than good. Such is the case with the adrenal hormone aldosterone, which stimulates the heart to pump harder, causing greater damage to the heart muscle.

3 Mar 2016

High-fat diet may make intestinal stem cells to become cancerous

Over the past decade, studies have found that obesity and eating a high-fat, high-calorie diet are significant risk factors for many types of cancer. Now, a new study from Whitehead Institute and MIT's Koch Institute for Integrative Cancer Research reveals how a high-fat diet makes the cells of the intestinal lining more likely to become cancerous.

3 Mar 2016

Severe anemia associated with increased risk for necrotizing enterocolitis in premature infants

A study from Emory University School of Medicine published in the Journal of the American Medical Association has found that severe anemia, but not red blood cell transfusions (RBC), is associated with an increased risk for a potentially fatal intestinal condition in premature infants.

2 Mar 2016

New BD Vacutainer Barricor Plasma Blood Collection tube earns CE mark approval

BD, a leading global medical technology company, announced today that it obtained the CE mark in Europe for a next-generation blood separation technology that is designed to enhance sample quality, improve laboratory efficiency and reduce laboratory turnaround time.

From BD (Becton, Dickinson and Company) 2 Mar 2016

Freestanding organ recovery facility for brain-dead donors increases organ transplant

Transplant surgeons report that obtaining organs from deceased organ donors costs much less and leads to a higher number of transplantable organs recovered when brain-dead donors are moved from the hospital to an independent, freestanding facility dedicated to organ recovery. Their study is published online as an "article in press" on the Journal of the American College of Surgeons website in advance of print publication later this year.

2 Mar 2016

New study finds link between vitamin D deficiency and aggressive prostate cancer

A new study provides a major link between low levels of vitamin D and aggressive prostate cancer. Northwestern Medicine research showed deficient vitamin D blood levels in men can predict aggressive prostate cancer identified at the time of surgery.

2 Mar 2016

"Neoehrlichiosis" Internationally Diagnosed And Successfully Treated In Patients Without Immunodeficiency For The First Time

The intercellular bacteria "Candidatus Neoehrlichia", as e.g. Borrelia, can be transferred by ticks. Approx. 4.2 % of indigenous ticks are infected with this rarely explored bacterium which, until today, has been exclusively identified as pathogenic bacterium in patients with an impairment of the immune system, such as in case of leukaemia, rheumatism or after organ transplantation.

1 Mar 2016

UAB researchers focus on five key areas to improve care of CVD patients

According to the Centers for Disease Control and Prevention, approximately 610,000 people die of heart disease in the United States every year — that's one in every four deaths. The impact of cardiovascular diseases is quite large.

28 Feb 2016

Graham School introduces new Master of Science Degree in Biomedical Informatics

Biomedical informatics, one of the world's fastest-growing interdisciplinary fields, is the latest graduate degree program offered by the University of Chicago Graham School of Continuing Liberal and Professional Studies.

27 Feb 2016

Pathology News and Research

Further Reading

Cause of amyloid beta pathology may be more versatile than previously known

Research provides important new insights into beginning stages of primary progressive aphasia

Specialized tests can help dermatologists provide individualized care for melanoma patients

Complex biomarker tests for molecularly targeted therapies lack evidentiary standards

Johns Hopkins Greenberg Bladder Cancer Institute awards grants for 10 bladder cancer research projects

Kessler Foundation's Silvana L. Costa awarded Switzer Research Fellowship for research on MS

P53 genetic variant heavily implicated in metabolism, new research finds

Study highlights new approach to produce coral snake antivenom from synthetically designed DNA

Cardiac reprogramming could shrink heart scar tissue, improve patients' heart function

Steroid use in late preterm delivery can reduce rate of neonatal respiratory complications

Study provides critical insight into Warburg effect

Researchers discover unexpected mechanism linked to aldosterone-induced heart damage

High-fat diet may make intestinal stem cells to become cancerous

Severe anemia associated with increased risk for necrotizing enterocolitis in premature infants

New BD Vacutainer Barricor Plasma Blood Collection tube earns CE mark approval

Freestanding organ recovery facility for brain-dead donors increases organ transplant

New study finds link between vitamin D deficiency and aggressive prostate cancer

"Neoehrlichiosis" Internationally Diagnosed And Successfully Treated In Patients Without Immunodeficiency For The First Time

UAB researchers focus on five key areas to improve care of CVD patients

Graham School introduces new Master of Science Degree in Biomedical Informatics

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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