Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Discovery could lead to better therapies for people with obsessive compulsive disorder

Research led by investigators in veterinary and human medicine has identified genetic pathways that exacerbate severity of canine compulsive disorder in Doberman pinschers, a discovery that could lead to better therapies for obsessive compulsive disorder in people.

27 Feb 2016

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

Juvenile idiopathic arthritis, or JIA, is the most common form of childhood arthritis. It appears to be an autoimmune disease, caused by antibodies attacking certain proteins in a person's own tissue. But no "autoantigens" -- the proteins triggering an immune attack -- have been linked to JIA.

27 Feb 2016

Light reflectance spectroscopy may lead to real-time tissue analysis during prostate cancer surgery

Researchers at UT Southwestern Medical Center have determined that light reflectance spectroscopy can differentiate between malignant and benign prostate tissue with 85 percent accuracy, a finding that may lead to real-time tissue analysis during prostate cancer surgery.

27 Feb 2016

Comorbid neuropathologies have major impact on cognition

Cognitive impairment is most likely to affect people with multiple types of brain pathology, irrespective of which particular pathologies they have, a study shows.

26 Feb 2016

Protein p62 acts as molecular brake to keep inflammation in check, avoid collateral damage

Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as p62 acts as a molecular brake to keep inflammation in check and avoid collateral damage.

26 Feb 2016

Genome sequencing shows association between STIs and Trachoma

For the first time, genome sequencing has been carried out on Chlamydia trachomatis (C. trachomatis), a bacteria responsible for the disease Trachoma - the world's leading infectious cause of blindness, according to a study in Nature Communications.

26 Feb 2016

Research finding could lay foundation for more accurate diagnosis for rare childhood brain tumor

An international research team has identified four likely new subtypes of a rare brain tumor using molecular techniques that lay the foundation for more accurate diagnosis and tailored therapies for the hard-to-treat cancer. Scientists at St. Jude Children's Research Hospital and the German Cancer Research Center led the study, results of which appear today in the scientific journal Cell.

26 Feb 2016

Research: Impaired immune response significantly involved in rare autoimmune diseases

In the context of the multicentre EU project "INTRICATE" under the management of Renate Kain of the Clinical Institute for Pathology of MedUni Vienna, the effects of infections on the generation of rare autoimmune diseases such as granulomatous polyangiitis (GPA), a systemic disease of the vascular system, are examined.

25 Feb 2016

IMP's Johannes Zuber receives German Cancer Prize 2016

Johannes Zuber, group leader at the Research Institute of Molecular Pathology (IMP) in Vienna, receives the German Cancer Prize 2016 in the category of experimental cancer research.

24 Feb 2016

Omega-3 fatty acids can lower risk of breast cancer in postmenopausal obese women

Omega-3 fatty acids may lower the risk of breast cancer in postmenopausal obese women, according to researchers.

24 Feb 2016

Ohio State researchers develop new approach to enhance heart function, cardiovascular performance

For the first time, scientists at The Ohio State University have engineered new calcium receptors for the heart to tune the strength of the heartbeat in an animal model. The research is published online by the journal Nature Communications.

24 Feb 2016

Immune cells may play greater role in Alzheimer's disease than originally thought

Immune cells that normally help us fight off bacterial and viral infections may play a far greater role in Alzheimer's disease than originally thought, according to University of California, Irvine neurobiologists with the Sue & Bill Gross Stem Cell Research Center and the Institute for Memory Impairments and Neurological Disorders.

24 Feb 2016

Texas Children's Hospital, Houston Methodist Hospital jointly release country's first rapid test for Zika virus

Collaboration between two Texas Medical Center institutions has resulted in today's release of the country's first hospital-based rapid tests for the Zika virus.

23 Feb 2016

Hiroshima University researchers identify new class of cancer-causing genetic variations

Researchers at Hiroshima University have opened the door to finding a new class of cancer-causing genetic variations.

23 Feb 2016

Virginia Tech scientist finds way to potentially track and stop viruses

Viruses are molecular thieves that take from their hosts under the cloak of darkness. But now a Virginia Tech scientist has found a way to not only track viral hijackers, but also potentially stop them from replicating.

19 Feb 2016

New way to analyze MRI data may offer treatment guidance for breast cancer patients

For women with the most common type of breast cancer, a new way to analyze magnetic resonance images (MRI) data appears to reliably distinguish between patients who would need only hormonal treatment and those who also need chemotherapy, researchers from Case Western Reserve University report.

19 Feb 2016

CHLA, Thermo Fisher Scientific agree to develop NGS-based panel for pediatric cancer research

Children's Hospital Los Angeles and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research. The assay would be CHLA's first NGS panel designed to target biomarkers associated with childhood cancers.

19 Feb 2016

DEK gene present in plasma can help predict outcomes for patients with head and neck cancer

Researchers at the University of Cincinnati have discovered that a human cancer-causing gene, called DEK, can be detected in the plasma of head and neck cancer patients. DEK may help doctors understand how a person's immune system could be used to treat cancer or predict outcomes for patients.

18 Feb 2016

Study demonstrating link between anal cancer and HPV infection published in Obstetrics & Gynecology

Researchers at Women & Infants Hospital, a Care New England hospital, recently published the results of a study demonstrating a connection between anal cancer and human papillomavirus (HPV) infection.

18 Feb 2016

Study finds gender differences in scholarly productivity among academic gynecologic oncologists

The differences between men and women seem to infiltrate yet another aspect of medicine with a study spearheaded at Women & Infants Hospital, a Care New England hospital, indicating that younger female gynecologic oncologists were less productive scholastically and, therefore, poorly represented in the higher academic ranks, than their male contemporaries.

18 Feb 2016

Pathology News and Research

Further Reading

Discovery could lead to better therapies for people with obsessive compulsive disorder

TTR protein causes autoimmune reaction in joints of juvenile idiopathic arthritis patients

Light reflectance spectroscopy may lead to real-time tissue analysis during prostate cancer surgery

Comorbid neuropathologies have major impact on cognition

Protein p62 acts as molecular brake to keep inflammation in check, avoid collateral damage

Genome sequencing shows association between STIs and Trachoma

Research finding could lay foundation for more accurate diagnosis for rare childhood brain tumor

Research: Impaired immune response significantly involved in rare autoimmune diseases

IMP's Johannes Zuber receives German Cancer Prize 2016

Omega-3 fatty acids can lower risk of breast cancer in postmenopausal obese women

Ohio State researchers develop new approach to enhance heart function, cardiovascular performance

Immune cells may play greater role in Alzheimer's disease than originally thought

Texas Children's Hospital, Houston Methodist Hospital jointly release country's first rapid test for Zika virus

Hiroshima University researchers identify new class of cancer-causing genetic variations

Virginia Tech scientist finds way to potentially track and stop viruses

New way to analyze MRI data may offer treatment guidance for breast cancer patients

CHLA, Thermo Fisher Scientific agree to develop NGS-based panel for pediatric cancer research

DEK gene present in plasma can help predict outcomes for patients with head and neck cancer

Study demonstrating link between anal cancer and HPV infection published in Obstetrics & Gynecology

Study finds gender differences in scholarly productivity among academic gynecologic oncologists

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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