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Pharma sells states on ‘Netflix model’ to wipe out hep C. But at what price?

When a long, black bus bearing the logo of drugmaker AbbVie rolls through Washington state next year, it will promote a new effort to eradicate hepatitis C infections.

25 Oct 2019

Study pinpoints cell types linked to age-related macular degeneration

Age-related macular degeneration is one of the leading causes of blindness in the elderly, affecting more than 2 million people in the United States and leading to progressive loss of central vision.

25 Oct 2019

Genetically definable subgroups of cancers sensitive to treatment

Precision oncology aims to use genetic features of a patient's tumor to tailor anti-cancer therapy. DNA mutations in a drug target have provided a number of therapeutic opportunities; however, there are many cancer types that do not have obvious targetable mutations.

24 Oct 2019

Universal influenza vaccine developed at Cornell is set for human clinical trials

A universal influenza vaccine with the potential to be longer lasting and more effective than commercially available vaccines is destined for human clinical trials, thanks to a $17.9 million grant from the National Institute of Allergy and Infectious Diseases.

24 Oct 2019

Newly discovered protein is key to recycling aging mitochondria

Aging, and the mechanics behind it, remains one of the most closely guarded secrets of life.

24 Oct 2019

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

Today, the Global Virus Network, a conglomerate of 52 "Centers of Excellence" and 9 Affiliates in 32 countries, which catalyzes collaborative research into diseases caused by every class of virus in humans and animals, announced the Wyss Institute for Biologically Inspired Engineering at Harvard University as a new Center of Excellence.

24 Oct 2019

New NPO formed to accelerate development of therapies for Shankopathies

Parents of children affected by Phelan-McDermid syndrome (PMS) announce the formation of CureSHANK, a nonprofit organization on a mission to accelerate drug development in PMS and other diseases related to the SHANK genes for which there are currently no FDA approved treatments.

23 Oct 2019

SLU research halts toxic protein linked to muscular dystrophy in animal models

There is no cure or treatment for facioscapulohumeral muscular dystrophy, an illness that starts with facial, shoulder and upper arm weakness and eventually affects nearly all skeletal muscles of those with the disease.

23 Oct 2019

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body's healthy tissues and organs.

23 Oct 2019

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease and HIV.

23 Oct 2019

Discovery sheds light on TNFα protein's role in impairing memory in Alzheimer's disease

Otago scientists have made an important discovery in understanding the role a particular protein plays to impair memory in Alzheimer's disease, which could lead to more effective treatment in future.

23 Oct 2019

New approach to treating high blood pressure

The key to treating blood pressure might lie in people who are “resistant” to developing high blood pressure even when they eat high salt diets, shows new research published in Experimental Physiology.

23 Oct 2019

Cantabio, LIH jointly investigate DJ-1 targeting compounds in immune associated diseases

DJ-1 is well known as an important target for the treatment of a number of diseases such as Parkinson's disease. Cantabio has been developing novel small molecule therapeutic program targeting the DJ-1 protein with a focus on Parkinson's and also exploring a number of other disease areas.

21 Oct 2019

Patients with diabetes may have worse lung infections

People with diabetes are at a higher risk of various complications, including worse respiratory diseases. One of the most dreaded lung diseases is the Middle East respiratory syndrome coronavirus (MERS-CoV), which emerged in Saudi Arabia in 2012.

21 Oct 2019

NAM launches new competition seeking breakthrough innovations to extend human life

The National Academy of Medicine, in collaboration with eight global organizations representing more than 40 countries and territories, announced today the launch of the Healthy Longevity Global Competition, a multiyear, multimillion-dollar international competition seeking breakthrough innovations to extend human health and function later in life.

21 Oct 2019

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

Despite advances in cancer survival, more than 90 percent of people with pancreatic cancer die within five years. Most patients with pancreatic tumors (and half of those with colorectal cancers) carry a mutation in the KRAS gene, which normally controls cell growth and death.

21 Oct 2019

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia and B-cell lymphoma.

21 Oct 2019

Cytel hosts Complex Innovative Trial Design Symposium and East Training in Boston

Cytel Inc., the leading global provider of innovative analytical software and consulting services to the life sciences industry, has announced that the Complex Innovative Trial Design Symposium and East Training will take place November 6–7 at Alexion’s headquarters in Boston, Massachusetts.

From Cytel 18 Oct 2019

Researchers find behavioral, biological similarities between compulsive overeating and addiction

Does yo-yo dieting drive compulsive eating? There may be a connection. According to Boston University School of Medicine researchers the chronic cyclic pattern of overeating followed by undereating, reduces the brain's ability to feel reward and may drive compulsive eating.

17 Oct 2019

Researchers obtain 3D structural snapshots of key regulator of cell biology

Some of the greatest insights into cancer and how to treat it come when basic scientists and cancer biologists and clinicians collaborate.

17 Oct 2019

Therapeutics News and Research

Pharma sells states on ‘Netflix model’ to wipe out hep C. But at what price?

Study pinpoints cell types linked to age-related macular degeneration

Genetically definable subgroups of cancers sensitive to treatment

Universal influenza vaccine developed at Cornell is set for human clinical trials

Newly discovered protein is key to recycling aging mitochondria

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

New NPO formed to accelerate development of therapies for Shankopathies

SLU research halts toxic protein linked to muscular dystrophy in animal models

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

Discovery sheds light on TNFα protein's role in impairing memory in Alzheimer's disease

New approach to treating high blood pressure

Cantabio, LIH jointly investigate DJ-1 targeting compounds in immune associated diseases

Patients with diabetes may have worse lung infections

NAM launches new competition seeking breakthrough innovations to extend human life

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

Cytel hosts Complex Innovative Trial Design Symposium and East Training in Boston

Researchers find behavioral, biological similarities between compulsive overeating and addiction

Researchers obtain 3D structural snapshots of key regulator of cell biology

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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