Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Novel gene therapy treatment proves safe, effective for factor VII deficiency

A single injection. That's all someone with a factor VII deficiency would need for a life-long cure, thanks to a new gene therapy treatment developed in a collaboration of researchers at the University of North Carolina and The Children's Hospital of Philadelphia.

20 Jan 2016

Scientists reveal why non-alcoholic steatohepatitis worsens in obese people

In results published on October 19, 2015 in the Journal of Lipid Research, a team of translational scientists at the Medical University of South Carolina report a new reason why non-alcoholic steatohepatitis (NASH) worsens in people who are obese.

20 Jan 2016

UCSF-led study shows increase in use of CT scans in patients with non-serious injuries

Twice as many patients with non-serious injuries, such as fractures or neck strain, are undergoing CT scans in emergency departments at California hospitals, according to a UCSF-led study, which tracked the use of the imaging from 2005 to 2013.

20 Jan 2016

IMP, WEHI scientists successfully characterize central regulator of plasma cell function

Plasma cells play a key role in our immune system. Now scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, and at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, succeeded in characterizing a central regulator of plasma cell function.

20 Jan 2016

WASF3 protein appears to be solid target for reducing cancer metastasis

A protein that is constantly expressed by cancer cells and quiescent in healthy ones appears to be a solid target for reducing cancer's ability to spread, scientists report.

19 Jan 2016

Combination of PARP inhibitors and c-MET may benefit breast cancer patients

Findings from a new study reveal that PARP inhibitors, an emerging class of drugs being studied in cancer clinical trials, may be enhanced by combining them with inhibitors targeting an oncogene known as c-MET which is overexpressed in many cancers.

19 Jan 2016

New sites opened across the South West for Alzheimer’s disease clinical trial

People with Alzheimer’s disease are helping with a ground-breaking government-funded trial but with new sites recently opened in the South West more people are being asked to take part in the study led by academics from the Universities of Bristol, Cambridge, Queen’s University Belfast and University College London, and hosted by North Bristol NHS Trust.

19 Jan 2016

UGA study helps solve mystery of how African trypanosomes communicate

While scientists have known for years that African trypanosomes cause sleeping sickness, they've been left scratching their heads as to how these tiny single-celled organisms communicate. A University of Georgia study, published Jan. 14 in the journal Cell, helps solve this mystery.

18 Jan 2016

Researchers identify origins of aggressive childhood lymphoma

The origins of a type of aggressive childhood lymphoma have been found, giving hope that new drugs could be designed to prevent the disease coming back after treatment.

18 Jan 2016

New report highlights resourcing issues in services for patients with bowel cancer

A new report published today (12 January 2016), by the Association of Coloproctology of Great Britain and Ireland (ACPGBI) and Bowel Cancer UK, highlights numerous areas of service provision that fall short of having the resources needed to provide optimum service and safety for bowel disease patients.

18 Jan 2016

Scientists identify origins of anaplastic large cell lymphoma

Anaplastic large cell lymphoma (ALCL) is a very aggressive cancer of the blood, which usually occurs as a tumour in lymph nodes, the skin, the lungs, the liver, and in soft tissue, and mainly affects children and young adults.

18 Jan 2016

MGH researchers find how metformin drug prevents progression of pancreatic cancer

Massachusetts General Hospital investigators may have uncovered a novel mechanism behind the ability of the diabetes drug metformin to inhibit the progression of pancreatic cancer.

17 Jan 2016

Researchers reveal totally new biological mechanism that underlies cancer

In a landmark study, researchers from the Broad Institute and Massachusetts General Hospital reveal a completely new biological mechanism that underlies cancer. By studying brain tumors that carry mutations in the isocitrate dehydrogenase (IDH) genes, the team uncovered some unusual changes in the instructions for how the genome folds up on itself.

13 Jan 2016

SIMnext introduces DR Doppler Dynamic Ultrasonography Training System

Health care professionals now have a new way of accessing ultrasound training in a mobile and affordable manner using the DR Doppler Dynamic Ultrasonography Training System (DR Doppler), a training tool from SIMnext, LLC, a medical simulation research and development company based in Peoria, Ill.

12 Jan 2016

Discoveries could lead to development of novel therapies to prevent C. diff infection

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile ("C. diff") -- the leading cause of hospital-acquired diarrhea in the United States.

12 Jan 2016

Study illuminates ways to better treat knee meniscus tears, other injuries

Fibrocartilage tissue in the knee is comprised of a more varied molecular structure than researchers previously appreciated, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania and the University of Delaware.

11 Jan 2016

New strategy may reduce growth of pancreatic cancers in patients with KRAS gene mutation

University of North Carolina Lineberger Comprehensive Cancer Center researchers have found a promising strategy that may limit the growth of pancreatic cancers in patients with a mutation in a gene called KRAS.

11 Jan 2016

New classification of coronary congenital diseases helps surgeons identify secondary defects

A new classification of coronary congenital diseases is set to help surgeons identify secondary defects in the operating theatre. The scheme is outlined in a novel European Society of Cardiology position paper published today in Cardiovascular Research.1 Clinical cardiologists will also know what to look for on cardiovascular images.

11 Jan 2016

Wyss Institute scientists develop better assay for testing hemostasis

Scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University have devised a better assay for testing blood's clotting tendency, also known as hemostasis, which could one day prove lifesaving in a variety of clinical situations in which a patient's health is jeopardized by abnormal blood coagulation and platelet function.

11 Jan 2016

SDPR gene may help to predict disease progression, serve as target for future breast cancer therapies

A gene that plays a role in the development of breast cancer to metastatic disease has been identified which may help to predict disease progression and serve as a target for the development of future breast cancer therapies.

11 Jan 2016

Pathology News and Research

Further Reading

Novel gene therapy treatment proves safe, effective for factor VII deficiency

Scientists reveal why non-alcoholic steatohepatitis worsens in obese people

UCSF-led study shows increase in use of CT scans in patients with non-serious injuries

IMP, WEHI scientists successfully characterize central regulator of plasma cell function

WASF3 protein appears to be solid target for reducing cancer metastasis

Combination of PARP inhibitors and c-MET may benefit breast cancer patients

New sites opened across the South West for Alzheimer’s disease clinical trial

UGA study helps solve mystery of how African trypanosomes communicate

Researchers identify origins of aggressive childhood lymphoma

New report highlights resourcing issues in services for patients with bowel cancer

Scientists identify origins of anaplastic large cell lymphoma

MGH researchers find how metformin drug prevents progression of pancreatic cancer

Researchers reveal totally new biological mechanism that underlies cancer

SIMnext introduces DR Doppler Dynamic Ultrasonography Training System

Discoveries could lead to development of novel therapies to prevent C. diff infection

Study illuminates ways to better treat knee meniscus tears, other injuries

New strategy may reduce growth of pancreatic cancers in patients with KRAS gene mutation

New classification of coronary congenital diseases helps surgeons identify secondary defects

Wyss Institute scientists develop better assay for testing hemostasis

SDPR gene may help to predict disease progression, serve as target for future breast cancer therapies

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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