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Temple researchers win NIH grant to study HIV-related neuroinflammation in context of opioid addiction

The National Institutes of Health has awarded a Temple research team a 5-year, $3.27 million grant to study neuroinflammation following HIV-infection in the context of opioid addiction.

16 Oct 2019

Brain's neural activity plays a role in human aging, life span

The brain's neural activity - long implicated in disorders ranging from dementia to epilepsy - also plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute at Harvard Medical School.

16 Oct 2019

Spectrum Health, MSU researchers aim to find new or better treatments for "orphan diseases"

The National Institutes of Health has awarded a Michigan State University researcher a $2.1 million, five-year grant to search vast databases of existing drugs.

16 Oct 2019

BioStreamline: Streamlining the development of next generation biotherapeutics

A collaboration to streamline the development of cost-effective next generation biotherapeutics will host a dissemination event at CPI.

From Fluidic Sciences and Sphere Bio 16 Oct 2019

Drug-light combination could offer better control over CAR T-cell treatments

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control.

15 Oct 2019

New molecular "clock" could help monitor life-altering development disorders in children

Scientists have developed a molecular "clock" that could reshape how pediatricians measure and monitor childhood growth and potentially allow for an earlier diagnosis of life-altering development disorders.

15 Oct 2019

New Penn Medicine study unravels the early makings of an exhausted T cell

The immune system struggles to defeat cancer or chronic infections because many of the T cells that leap into action end up "exhausted," rendering them ineffective against disease.

14 Oct 2019

Simple way to effectively transport medication into the brain identified

For the first time, scientists have identified a simple way that can effectively transport medication into the brain - which could lead to improved treatments for neurological and neurodegenerative diseases.

11 Oct 2019

Research finds drugs for better long-term treatment of poorly controlled asthma

The waning effectiveness of drugs over time continues to be a major challenge in treating diseases, including asthma.

11 Oct 2019

Genetic oscillator captures changes in gut microbiome growth patterns

For all the attention the human microbiome has been getting over the last few years, one aspect of such research rarely makes headlines: the difficulty of observing how it changes over time in response to various stimuli.

11 Oct 2019

New tool records and tracks microbiome growth

Over the past years, the human microbiome has gained immense popularity due to its role in shaping one’s health. It is essential for human development, nutrition, and immunity. That’s why many studies have focused on how to improve one’s health by targeting or enhancing the microbiome.

11 Oct 2019

Study pinpoints a gene that allows chlamydia to pick up DNA from host environment

According to the Centers for Disease Control and Prevention, chlamydia trachomatis is the most commonly reported sexually transmitted bacterial disease in the U.S., totaling 1.7 million cases in 2017. Rates are highest among teenagers and young adults. Left untreated, chlamydia can cause blindness and sterility.

10 Oct 2019

CRISPR RNA-cutting enzyme programmed to destroy viruses in human cells

Many of the world's most common or deadly human pathogens are RNA-based viruses -- Ebola, Zika and flu, for example -- and most have no FDA-approved treatments.

10 Oct 2019

BIA Separations launches CORNERSTONE Exosome Process Development Solution

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of its CORNERSTONE Exosome Process Development Solution, designed to help drug-developers overcome critical development bottlenecks in the preparation of exosomes for clinical use.

10 Oct 2019

β-blockers could regenerate infant heart muscle, mitigate effects of congenital heart disease

Surgery can mend congenital heart defects shortly after birth, but those babies will carry a higher risk of heart failure throughout the rest of their lives. Yet, according to a Science Translational Medicine study published today by UPMC Children's Hospital of Pittsburgh researchers, β-blockers could supplement surgery to regenerate infant heart muscle and mitigate the lasting effects of congenital heart disease.

9 Oct 2019

Using tape strips to obtain skin biomarkers in children with atopic dermatitis

Applying strips of adhesive tape to skin lesions and non-lesional skin is a non-invasive way to obtain biomarkers to track the severity of early-onset pediatric eczema or atopic dermatitis in infants and young children, researchers report for the first time.

9 Oct 2019

More sensitive electrophysiology tools needed to study cancer cell populations

Bioelectricity of Cancer, a special issue of the peer-reviewed journal Bioelectricity, has just been published. Two promising discoveries are well delineated: an ultra-sensitive tool to detect cancer and a new therapeutic target for cancer immunotherapy.

9 Oct 2019

Insilico and CTFH team up to expedite first-in-class therapeutics using AI platform

Insilico Medicine, a company developing an end-to-end drug discovery pipeline utilizing the latest advances in deep learning, has entered into a two-program research collaboration agreement with Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd..

9 Oct 2019

Unique immune cell linked to remission in patients with triple negative breast cancer

A unique type of immune cell has been discovered in human breast tissue, and breast cancer patients with more of these cells are more likely to survive, finds new research from the Francis Crick Institute and King's College London.

From The Francis Crick Institute 9 Oct 2019

Study explores steroid prescribing rates for patients with inflammatory bowel disease

Steroid therapy is commonly used to treat acute attacks of the inflammatory bowel diseases ulcerative colitis and Crohn's disease; however, because it does not provide long-term benefits and it carries a risk of serious side effects, it should not be used to treat inflammatory bowel disease for more than three months.

9 Oct 2019

Therapeutics News and Research

Temple researchers win NIH grant to study HIV-related neuroinflammation in context of opioid addiction

Brain's neural activity plays a role in human aging, life span

Spectrum Health, MSU researchers aim to find new or better treatments for "orphan diseases"

BioStreamline: Streamlining the development of next generation biotherapeutics

Drug-light combination could offer better control over CAR T-cell treatments

New molecular "clock" could help monitor life-altering development disorders in children

New Penn Medicine study unravels the early makings of an exhausted T cell

Simple way to effectively transport medication into the brain identified

Research finds drugs for better long-term treatment of poorly controlled asthma

Genetic oscillator captures changes in gut microbiome growth patterns

New tool records and tracks microbiome growth

Study pinpoints a gene that allows chlamydia to pick up DNA from host environment

CRISPR RNA-cutting enzyme programmed to destroy viruses in human cells

BIA Separations launches CORNERSTONE Exosome Process Development Solution

β-blockers could regenerate infant heart muscle, mitigate effects of congenital heart disease

Using tape strips to obtain skin biomarkers in children with atopic dermatitis

More sensitive electrophysiology tools needed to study cancer cell populations

Insilico and CTFH team up to expedite first-in-class therapeutics using AI platform

Unique immune cell linked to remission in patients with triple negative breast cancer

Study explores steroid prescribing rates for patients with inflammatory bowel disease

Industry Focus eBook - Biotechnology (4th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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