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New model predicts mRNA protein production, accelerating drug and vaccine discovery

A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types. The new advance, developed through an academic-industrial partnership between The University of Texas at Austin and Sanofi, helps predict how much protein cells will produce, which can minimize the need for trial-and-error experimentation, accelerating the next generation of mRNA therapeutics.

26 Jul 2025

New study uncovers how prior obesity impacts viral consequences

A study comparing the effects of SARS-CoV-2 infection in lean and obese primates found different long-term consequences of the virus depending on prior obesity and metabolic disease. The results, which also highlighted how widespread long COVID symptoms are in animals, were published July 24th in the open-access journal PLOS Pathogens by Charles Roberts of Oregon Health & Science University, USA, and colleagues.

25 Jul 2025

Different anti-PD-L1 antibodies show varied results in tumor growth inhibition

Immune checkpoint inhibitors (ICIs), a powerful form of immunotherapy, have revolutionized cancer treatment by unleashing the body's own immune system to fight tumors.

24 Jul 2025

New study reveals high lifetime exposure to hepatitis B and C in Ukraine

A study just published on Eurosurveillance has found evidence of substantial lifetime exposure to hepatitis B and C viruses in Ukraine in a 2021 nationwide, representative sample of the population, with findings also suggesting significant ongoing circulation of these viruses.

24 Jul 2025

Promising therapeutic approach identified for multiple myeloma

Researchers at Uppsala University have identified a promising therapeutic approach for the challenging blood cancer multiple myeloma.

24 Jul 2025

Forever chemicals cross placenta and breast milk affecting babies’ immunity

New research reveals that tiny amounts of PFAS-widely known as "forever chemicals"-cross the placenta and breast milk to alter infants' developing immune systems, potentially leaving lasting imprints on their ability to fight disease.

23 Jul 2025

New llama antibody-based treatment improves brain function in schizophrenia models

While current treatments for schizophrenia - a mental illness affecting 1% of the world's population - can reduce certain symptoms, they have little effect on the cognitive deficits affecting the daily life of patients.

23 Jul 2025

New diagnostic test identifies head and neck cancer patients curable by surgery alone

Researchers developed a diagnostic test based on the LIMA1-alpha protein to distinguish patients with head and neck squamous cell carcinoma who can be cured with surgery alone, without the need for radiation or chemotherapy.

23 Jul 2025

Long-term air pollution exposure triggers allergic immune responses in the lungs

Air pollution is a global health concern, with over 90% of the world's population breathing air that exceeds World Health Organization safety standards.

23 Jul 2025

New menstrual blood test detects endometriosis with five times greater sensitivity

Almost 200 million people, including children, around the world have endometriosis, a chronic disease in which the lining of the uterus grows outside of the uterus.

22 Jul 2025

Dual cancer drugs restore memory and rewire brain cells in Alzheimer’s mouse models

Researchers identified a combination of two existing cancer drugs, letrozole and irinotecan, that reversed Alzheimer’s disease-related changes in brain cell networks and improved memory in mouse models. The study supports a multi-cell-type, network-correcting strategy as a promising path for future Alzheimer’s treatments.

22 Jul 2025

New antibody therapy offers hope for fragile patients with Fanconi anemia

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a phase 1 clinical trial has shown.

22 Jul 2025

Toti-N-Seq breakthrough enables universal and scalable single-cell profiling

The rapid advancement of single-cell and single-nucleus RNA sequencing (sc/snRNA-seq) has opened unprecedented windows into cellular diversity, yet existing methods for multiplexing samples struggle with scalability and accuracy.

22 Jul 2025

Study identifies mechanism that helps prevent cancer, neurodegeneration, and premature aging

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, neurodegeneration, and premature aging.

21 Jul 2025

Maternal RSV vaccination linked to sharp drop in infant lung infections

Vaccination of pregnant women has been linked to a drop in newborns being admitted to hospital with a serious lung infection, research suggests.

18 Jul 2025

New monoclonal antibody enhances immune response by selectively targeting Tregs

A new research paper was published in Volume 16 of Oncotarget on July 9, 2025, titled "A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment."

17 Jul 2025

University of Zurich develops molecules to rapidly detect dangerous bacteria

Rapidly identifying certain bacteria allows antibiotic treatments to be optimised. A team from the University of Zurich, supported by the SNSF, has developed molecules to detect and capture certain species.

16 Jul 2025

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

University of New Mexico researchers have received funding to launch an early-stage clinical trial of a vaccine engineered to clear pathological tau protein from the brains of patients suffering from Alzheimer's dementia.

15 Jul 2025

WEE1 identified as a key driver of immune resistance in cancer

Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues.

15 Jul 2025

New autoimmune target identified in pediatric idiopathic nephrotic syndrome

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein crucial for kidney cell structure—as a significant factor in INS.

14 Jul 2025

Antibodies News and Research

New model predicts mRNA protein production, accelerating drug and vaccine discovery

New study uncovers how prior obesity impacts viral consequences

Different anti-PD-L1 antibodies show varied results in tumor growth inhibition

New study reveals high lifetime exposure to hepatitis B and C in Ukraine

Promising therapeutic approach identified for multiple myeloma

Forever chemicals cross placenta and breast milk affecting babies’ immunity

New llama antibody-based treatment improves brain function in schizophrenia models

New diagnostic test identifies head and neck cancer patients curable by surgery alone

Long-term air pollution exposure triggers allergic immune responses in the lungs

New menstrual blood test detects endometriosis with five times greater sensitivity

Dual cancer drugs restore memory and rewire brain cells in Alzheimer’s mouse models

New antibody therapy offers hope for fragile patients with Fanconi anemia

Toti-N-Seq breakthrough enables universal and scalable single-cell profiling

Study identifies mechanism that helps prevent cancer, neurodegeneration, and premature aging

Maternal RSV vaccination linked to sharp drop in infant lung infections

New monoclonal antibody enhances immune response by selectively targeting Tregs

University of Zurich develops molecules to rapidly detect dangerous bacteria

UNM researchers get $1 million grant to launch early clinical trial for Alzheimer’s vaccine

WEE1 identified as a key driver of immune resistance in cancer

New autoimmune target identified in pediatric idiopathic nephrotic syndrome

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