Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity

Self-amplifying RNA (saRNA) is an advanced platform for nucleic acid vaccine development. The backbone is typically derived from an alphaviral genome and encodes a gene of interest (GOI) and a viral replicase that can amplify the genomic and subgenomic RNA.

30 Aug 2021

Researchers unveil a new method to fabricate a highly conductive and elastic nanomembrane

"Skin electronics" are thin flexible electronics that could be mounted onto the skin. While it may sound like something out of science fiction, it is anticipated that soon such devices can serve as next-generation devices with a wide range of applications such as health monitoring, health diagnosis, virtual reality, and human-machine interface.

27 Aug 2021

Nanotechnology provides novel solutions against zoonotic viruses

Therefore, scientists functionalize nanoparticles to act against these pathogenic viruses in a clinical strategy. In a recent review published in the journal Microbial Pathogenesis, researchers look at the novel solutions against zoonotic viruses provided by nanotechnology.

23 Aug 2021

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

The safety, immunogenicity, and efficacy of the vaccines in adolescents are largely unknown. Now, a new study published in the New England Journal of Medicine evaluates the safety and efficacy of the mRNA-1273 vaccine in adolescents (12-17 years of age).

16 Aug 2021

Surfactant-coated nanoparticle applications in nanomedicine and food

A group of researchers critically review the use of surfactant-coated nanoparticles in the fields of nanomedicine and food nanotechnology.

8 Aug 2021

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Modified mRNA combined with lipid nanoparticles may be beneficial in boosting adaptive immunity against SARS-CoV-2. Research led by Botond Z. Igyártó from Thomas Jefferson University’s Department of Microbiology and Immunology in Pennsylvania recently found that the lipid nanoparticles induce protective adaptive immune responses with antibody titers against lethal doses of the virus.

5 Aug 2021

Diagnosis of viral infections using micro and nanoscale technologies

In a recent study, the authors provide a review on both micro- and nanoscale technologies that advanced the diagnosis of viral diseases.

3 Aug 2021

Discovery may enable the development of new therapies to kill aggressive cancer cells

Vanderbilt faculty and researchers are looking for the "Achilles' heel" of the cancer cells that survive initial chemotherapy.

3 Aug 2021

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

A pioneering study reports on the interaction of a tailored titanium oxide nanoparticle (NP) with the full-length SARS-CoV-2 non-structural protein 1 (nsp1). This should be of value in developing new therapeutic tools against coronaviruses that act by targeting their proteins. It could also help map the structure of activated proteins.

2 Aug 2021

MIT engineers create new diagnostic nanoparticle that can pinpoint tumor location

Most of the tests that doctors use to diagnose cancer -- such as mammography, colonoscopy, and CT scans -- are based on imaging. More recently, researchers have also developed molecular diagnostics that can detect specific cancer-associated molecules that circulate in bodily fluids like blood or urine.

16 Jul 2021

mRNA-based COVID-19 vaccine CV07050101 demonstrates limited immunogenicity in non-human primates

Scientists from the US and Germany have recently evaluated the efficacy of an mRNA-based COVID-19 vaccine candidate, CV07050101, in inducing humoral and cellular immune responses in non-human primates. The study reveals that prime-boost immunization with the vaccine candidate induces only limited immunity against SARS-CoV-2.

12 Jul 2021

Study examines the effectiveness of fluorescent labels used to monitor liposome accumulation in tumors

Dmitri Simberg, PhD, an associate professor in the Department of Pharmaceutical Sciences in the Skaggs School of Pharmacy and a CU Cancer Center member, has released the results of a new study of the effectiveness of different types of fluorescent labels used to monitor the accumulation of liposomes in tumors.

8 Jul 2021

Nikalyte Announces New Partnership with Life Science Group Calibre Scientific

Nanoparticle deposition specialists, Nikalyte Ltd announced that the company has signed a partnership agreement with global life sciences group Calibre Scientific.

From Nikalyte Ltd 8 Jul 2021

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

In a recent study published in the journal Science Immunology, scientists have revealed that the presence of CD8+ T cells against conserved epitopes of seasonal coronaviruses is associated with mild coronavirus disease 2019 (COVID-19). These immune cells exhibit a memory phenotype and provide protection against severe disease.

7 Jul 2021

Novavax COVID-19 vaccine demonstrates ~90% efficacy against SARS-CoV-2

The findings reveal that the two-dose regimen of the vaccine is almost 90% effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, the vaccine shows high efficacy against the B.1.1.7 variant (Alpha) of SARS-CoV-2.

5 Jul 2021

IU researchers developing noninvasive brain stimulation technique to treat neurological disorders

Indiana University School of Medicine researchers are developing a new, noninvasive brain stimulation technique to treat neurological disorders, including pain, traumatic brain injury (TBI), epilepsy, Parkinson's disease, Alzheimer's disease and more.

2 Jul 2021

Intranasal COVID-19 vaccine developed from bacterial extracellular vesicle induces robust antibody response in preclinical trials

A team of US-based scientists recently developed a novel vaccine candidate against SARS-CoV-2, the causative pathogen of COVID-19. The vaccine is composed of extracellular vesicles of Salmonella typhimurium incorporated with the spike receptor-binding domain (RBD) of SARS-CoV-2. Upon intranasal administration in hamsters, the vaccine induces strong blood antibody titers and protects against severe COVID-19.

30 Jun 2021

Nanotechnology and the fight against COVID-19

In a review paper published in the open-access MDPI journal Viruses, a team of researchers explored the potential of nanotechnology to alleviate the current and future coronavirus burden. The team focused on its potential role in the detection, diagnosis, protection, and treatment of SARS-CoV-2 infection.

29 Jun 2021

Research findings on the links between air pollution and neurodegeneration

There is growing awareness that air pollutants are playing a critical role in the development of neurodegenerative diseases.

22 Jun 2021

Use of nanotherapeutics in treating coronavirus diseases

Despite advancements in medicine, viral infections still pose a huge threat to human health and are a significant concern for global public health systems.

22 Jun 2021

Nanoparticle News and Research

Further Reading

Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity

Researchers unveil a new method to fabricate a highly conductive and elastic nanomembrane

Nanotechnology provides novel solutions against zoonotic viruses

Moderna COVID-19 vaccine safe and efficacious in adolescents according to a new study

Surfactant-coated nanoparticle applications in nanomedicine and food

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Diagnosis of viral infections using micro and nanoscale technologies

Discovery may enable the development of new therapies to kill aggressive cancer cells

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

MIT engineers create new diagnostic nanoparticle that can pinpoint tumor location

mRNA-based COVID-19 vaccine CV07050101 demonstrates limited immunogenicity in non-human primates

Study examines the effectiveness of fluorescent labels used to monitor liposome accumulation in tumors

Nikalyte Announces New Partnership with Life Science Group Calibre Scientific

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

Novavax COVID-19 vaccine demonstrates ~90% efficacy against SARS-CoV-2

IU researchers developing noninvasive brain stimulation technique to treat neurological disorders

Intranasal COVID-19 vaccine developed from bacterial extracellular vesicle induces robust antibody response in preclinical trials

Nanotechnology and the fight against COVID-19

Research findings on the links between air pollution and neurodegeneration

Use of nanotherapeutics in treating coronavirus diseases

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

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