Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Experts to study how improved support for dementia carers can enhance quality of life

Experts will explore how improved support and powers for people caring for loved-ones with dementia can improve quality of life for both patients and carers around the UK.

23 Sep 2014

Simple test based on movement and thought can help identify Alzheimer's risk before signs of dementia

York University researchers say a simple test that combines thinking and movement can help to detect heightened risk for developing Alzheimer's disease in a person, even before there are any telltale behavioural signs of dementia.

23 Sep 2014

TauRx achieves target enrolment in second LMTX Phase III clinical trial for Alzheimer's disease

TauRx Therapeutics Ltd has achieved its target enrolment of 700 subjects with mild Alzheimer's disease into the second of its two Phase III clinical trials of LMTX, a tau aggregation inhibitor, for the treatment of Alzheimer's disease.

22 Sep 2014

Researchers discover key cell-signaling pathway that contributes to development of Alzheimer's disease

Researchers at Jacksonville's campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer's disease patients as well as loss of communication between neurons - both significant contributors to this type of dementia.

21 Sep 2014

Research findings provide more details about earliest stages of neurodegenerative disease

The link between a protein typically associated with Alzheimer's disease and its impact on memory and cognition may not be as clear as once thought, according to a new study from the University of Wisconsin-Madison's Waisman Center.

19 Sep 2014

People who experience migraine in middle age may develop movement disorders later in life

A new study suggests that people who experience migraine in middle age may be more likely to develop Parkinson's disease, or other movement disorders later in life. Those who have migraine with aura may be at double the risk of developing Parkinson's, according to the study published in the September 17, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

18 Sep 2014

Study suggests potential treatment for cardiovascular disease in people with apoE4 gene variant

Researchers at UT-Southwestern Medical Center have found that the most common variant of the circulating protein apolipoprotein E, called apoE3, helps repair the lining of blood vessels. Individuals with another variant, called apoE4, do not get the benefit of this repair, putting them at higher risk for cardiovascular disease.

18 Sep 2014

State highlights: N.Y. sues drugmaker over Alzheimer's drug switch; Ariz. Republican resigns over Medicaid remarks

New York State's attorney general filed an antitrust lawsuit on Monday seeking to stop a pharmaceutical company from forcing patients with Alzheimer's disease to switch to a new version of a widely used drug. The lawsuit contends that the switch is designed to blunt competition from low-priced generic versions of the medication (Pollack, 9/15).

17 Sep 2014

Research findings could help explain how some people stave off dementia

The human brain is capable of a neural workaround that compensates for the buildup of beta-amyloid, a destructive protein associated with Alzheimer's disease, according to a new study led by researchers at the University of California, Berkeley.

17 Sep 2014

Lilly, AstraZeneca partner to co-develop and commercialize potential Alzheimer's disease treatment

Eli Lilly and Company and AstraZeneca today announced an agreement to co-develop and commercialize AZD3293, an oral beta secretase cleaving enzyme (BACE) inhibitor currently in development as a potential treatment for Alzheimer's disease.

16 Sep 2014

Adequate levels of vitamin E critical for young, elderly and pregnant women

Amid conflicting reports about the need for vitamin E and how much is enough, a new analysis published today suggests that adequate levels of this essential micronutrient are especially critical for the very young, the elderly, and women who are or may become pregnant.

16 Sep 2014

New class of compounds protect brain cells from traumatic brain injury

A new class of compounds has now been shown to protect brain cells from the type of damage caused by blast-mediated traumatic brain injury (TBI).

12 Sep 2014

Research gives scientists new insight into evolution of gibbon genome

A team led by an Oregon Health & Science University researcher has sequenced and annotated the genome of the only ape whose DNA had yet to be sequenced - the gibbon, an endangered small ape that inhabits the tropical forests of Southeast Asia.

11 Sep 2014

Study looks at blood type and risk of cognitive impairment

People with blood type AB may be more likely to develop memory loss in later years than people with other blood types, according to a study published in the September 10, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

11 Sep 2014

Pollution in many cities threatens brain development in children

Pollution in many cities threatens the brain development in children. Findings by University of Montana Professor Dr. Lilian Calder-n-Garcidue-as, MA, MD, Ph.D., and her team of researchers reveal that children living in megacities are at increased risk for brain inflammation and neurodegenerative changes, including Alzheimer's or Parkinson's disease.

11 Sep 2014

Sanofi contributes $2.5 million to CCNA for dementia research

Sanofi announced today its $2.5 million contribution to co-fund the Canadian Consortium on Neurodegeneration in Aging, a partnership officially launched in Montreal today in the presence of The Honourable Rona Ambrose, Minister of Health.

10 Sep 2014

New way to preserve flexibility and resilience of the brain

As Alzheimer's disease progresses, it kills brain cells mainly in the hippocampus and cortex, leading to impairments in "neuroplasticity," the mechanism that affects learning, memory, and thinking.

10 Sep 2014

Alzheimer's disease report success in harnessing mouse's immune system to attack toxic proteins

Alzheimer's disease experts at NYU Langone Medical Center and elsewhere are reporting success in specifically harnessing a mouse's immune system to attack and remove the buildup of toxic proteins in the brain that are markers of the deadly neurodegenerative disease.

9 Sep 2014

AMPK gene can slow aging process when activated remotely in key organ systems

UCLA biologists have identified a gene that can slow the aging process throughout the entire body when activated remotely in key organ systems.

9 Sep 2014

Scientists apply iPS cell technology to Huntington's disease transgenic monkey model

Creating induced pluripotent stem cells or iPS cells allows researchers to establish "disease in a dish" models of conditions ranging from Alzheimer's disease to diabetes.

8 Sep 2014

Alzheimer's Disease News and Research

Further Reading

Experts to study how improved support for dementia carers can enhance quality of life

Simple test based on movement and thought can help identify Alzheimer's risk before signs of dementia

TauRx achieves target enrolment in second LMTX Phase III clinical trial for Alzheimer's disease

Researchers discover key cell-signaling pathway that contributes to development of Alzheimer's disease

Research findings provide more details about earliest stages of neurodegenerative disease

People who experience migraine in middle age may develop movement disorders later in life

Study suggests potential treatment for cardiovascular disease in people with apoE4 gene variant

State highlights: N.Y. sues drugmaker over Alzheimer's drug switch; Ariz. Republican resigns over Medicaid remarks

Research findings could help explain how some people stave off dementia

Lilly, AstraZeneca partner to co-develop and commercialize potential Alzheimer's disease treatment

Adequate levels of vitamin E critical for young, elderly and pregnant women

New class of compounds protect brain cells from traumatic brain injury

Research gives scientists new insight into evolution of gibbon genome

Study looks at blood type and risk of cognitive impairment

Pollution in many cities threatens brain development in children

Sanofi contributes $2.5 million to CCNA for dementia research

New way to preserve flexibility and resilience of the brain

Alzheimer's disease report success in harnessing mouse's immune system to attack toxic proteins

AMPK gene can slow aging process when activated remotely in key organ systems

Scientists apply iPS cell technology to Huntington's disease transgenic monkey model

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