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Exploring vaccine effectiveness against SARS-CoV-2 Omicron and Delta variants in adolescents

A new study assessed the effectiveness of the BNT162b2 SARS-CoV-2 vaccine against Delta and Omicron variants in adolescents.

12 Apr 2022

Safety, reactogenicity, and immunogenicity of the BNT and half-m1273 mRNA COVID-19 vaccines given as a fourth dose booster

Researchers evaluated the immunogenicity of Pfizer’s BNT162b2 and Moderna’s mRNA-1273 vaccines offered as the fourth dose against SARS-CoV-2.

12 Apr 2022

Differences in symptoms and risk of hospitalization following infection with Omicron or Delta SARS-CoV-2 variants among vaccinated people

A recent study assessed the prevalence of SARS-CoV-2 symptoms and the risk of hospitalization in vaccinated individuals infected with SARS-CoV-2 Omicron and Delta variants.

12 Apr 2022

SARS-CoV-2 mutations change proteasome processing to alter CD8+ T cell responses

Researchers identified mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleoproteins (NP) epitope flanking regions and their potential effects on CD8+ T cell activation.

12 Apr 2022

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

A recent study illustrated the enhanced distinct clustering of pseudotyped particles (PPs) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

12 Apr 2022

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

In a recent study researchers evaluated the T cell responses elicited by full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein vaccine NVX-CoV2373.

12 Apr 2022

Scientists find critical role for Hippo signaling pathway in COVID-19 pathogenesis

A recent article posted to the bioRxiv* preprint server illustrated that the activation of the Hippo signaling pathway upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection aids the host antiviral response.

11 Apr 2022

Inflammation weakens odor signals and may be responsible for COVID19 loss of smell

Anosmia, the loss of smell, is a frequent and often long-term symptom associated with COVID-19 that can severely burden a person's quality of life, making it extremely difficult to taste foods, detect airborne hazards in the environment and carry out other functions dependent on the sense.

11 Apr 2022

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Researchers used cryogenic electron microscopy (cryo-EM) to determine the structure of the spike (S) protein of BA.2 sub-variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and compared them with previously determined S structures of Omicron's BA.1 sub-variant.

11 Apr 2022

Patients with allergic disorders have greater risk of high blood pressure and coronary heart disease

Data from the National Health Interview Survey demonstrated adults with a history of allergic disorders have an increased risk of high blood pressure and coronary heart disease, with the highest risk seen in Black male adults.

11 Apr 2022

The relationship between household type, COVID-19 and mental health

Researchers demonstrated the relationship between the built environment with a common element and coronavirus disease 2019 (COVID-19) transmission and mental health conditions.

11 Apr 2022

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

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11 Apr 2022

New study reveals oral opaganib's potent in vitro activity against Omicron

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced study results in which opaganib (ABC294640), a leading oral drug candidate for hospitalized patients with moderate to severe COVID-19, was observed to have potent in vitro efficacy against the Omicron SARS-CoV-2 variant, while maintaining host cell viability.

11 Apr 2022

COVID-19 increases risk of bleeding, DVT, and pulmonary embolism

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11 Apr 2022

Safety of COVID booster doses and obstetric outcomes in pregnancy

Researchers determine whether there is any risk posed to pregnant women who have received a booster vaccine dose during pregnancy.

11 Apr 2022

Nanocell COVID-19 vaccine elicits potent neutralizing response

A new study describes the high level of neutralizing antibodies elicited by a nanocell vaccine against SARS-CoV-2 in vitro, in vivo, and human studies.

11 Apr 2022

Chromatin accessibility as an early marker of severe COVID-19

A new study explores the possible use of chromatin remodeling in predicting a severe clinical trajectory for COVID-19.

11 Apr 2022

COVID-19 vaccines and reports of menstrual disorders

A new study estimates the potential relationship between COVID-19 vaccines and menstrual disorders.

11 Apr 2022

International study offers insight into occurrence of acute myocarditis during COVID-19 hospitalization

Acute myocarditis, inflammation of the heart muscle typically triggered by a virus, occurred in about two out of every 1,000 people hospitalized with COVID-19, and was associated with more severe illness and complications in people with COVID-19, especially among people who also had pneumonia, according to new research published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

11 Apr 2022

Study identifies a novel class of angiotensin receptor blockers that interfere with SARS-CoV-2 spike – ACE2 interaction

Scientists have discovered a new generation of angiotensin receptor blockers that may be used to treat coronavirus disease 2019.

11 Apr 2022

Respiratory News and Research

Exploring vaccine effectiveness against SARS-CoV-2 Omicron and Delta variants in adolescents

Safety, reactogenicity, and immunogenicity of the BNT and half-m1273 mRNA COVID-19 vaccines given as a fourth dose booster

Differences in symptoms and risk of hospitalization following infection with Omicron or Delta SARS-CoV-2 variants among vaccinated people

SARS-CoV-2 mutations change proteasome processing to alter CD8+ T cell responses

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

Scientists find critical role for Hippo signaling pathway in COVID-19 pathogenesis

Inflammation weakens odor signals and may be responsible for COVID19 loss of smell

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Patients with allergic disorders have greater risk of high blood pressure and coronary heart disease

The relationship between household type, COVID-19 and mental health

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

New study reveals oral opaganib's potent in vitro activity against Omicron

COVID-19 increases risk of bleeding, DVT, and pulmonary embolism

Safety of COVID booster doses and obstetric outcomes in pregnancy

Nanocell COVID-19 vaccine elicits potent neutralizing response

Chromatin accessibility as an early marker of severe COVID-19

COVID-19 vaccines and reports of menstrual disorders

International study offers insight into occurrence of acute myocarditis during COVID-19 hospitalization

Study identifies a novel class of angiotensin receptor blockers that interfere with SARS-CoV-2 spike – ACE2 interaction

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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