DNA News and Research

RSS

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington's disease, a neurodegenerative disorder that attacks brain cells.

7 Jul 2021

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Scientists at the University of Cambridge have identified rare genetic variants - carried by one in 3,000 people - that have a larger impact on the risk of developing type 2 diabetes than any previously identified genetic effect.

7 Jul 2021

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Together with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called APOBEC proteins are important factors in the body's immune response and offer fast and effective protection against a large number of DNA and RNA viruses.

7 Jul 2021

Uncovering cellular mechanism related to gene silencing therapies

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

A recent study by scientists from Japanese universities has shown that the shape of cell-derived nanoparticles, known as "extracellular vesicles" (EVs), in body fluids could be a biomarker for identifying types of cancer.

7 Jul 2021

Study explores the intersection of culture and health among Mexican women and children

As we move through life, our bodies get older. Aging is inevitable, but how fast it happens can vary considerably. Physical and environmental stressors can accelerate the process, and culture may interact with biology in ways that are not fully explored.

7 Jul 2021

Skin pigmentation mechanism confers major protection against UV-related cancers

A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH).

7 Jul 2021

New discovery provides clues to elucidate the pathogenesis of muscle diseases

A research collaboration based in Kumamoto University, Japan has discovered that muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body.

6 Jul 2021

NYUAD researchers unlock an epigenetic code that allows liver regeneration

NYU Abu Dhabi researchers uncovered a code that sets the genome of the liver to account for the remarkable ability for this organ to regenerate.

6 Jul 2021

Comprehensive genetic study provides new insights on cleft lip and palate

Cleft lip and palate is one of the most common congenital malformations. Its causes are mainly genetic. However, it is still largely unknown exactly which genes are affected.

6 Jul 2021

Researchers unravel mechanisms that produce individualized metabolism in leukemia

A research collaboration based in Kumamoto University (Japan) has shown that lysine-specific demethylase 1 (LSD1), an enzyme involved in gene expression, produces individualized metabolism depending on the type of acute myeloid leukemia cells.

6 Jul 2021

Brain cells snap DNA strands in numerous locations to make memories

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

6 Jul 2021

New method expands view into activity of single cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.

6 Jul 2021

Castration of male sheep slows DNA aging

Most of us are familiar with the fact that women live longer than men. But fellas, if we told you there was one thing that could be done to increase your lifespan, would you do it?

6 Jul 2021

Study examines evolution and avidity of anti-SARS-CoV-2 IgG antibodies after mRNA vaccination

New research released on the medRxiv* preprint server has measured antibody responses in 71 mRNA vaccinated adults (54 vaccinated with Pfizer and 17 vaccinated with Moderna).

6 Jul 2021

Developing a face mask that can detect COVID-19

A face mask has been developed that can detect COVID-19. News-Medical spoke to the researchers behind this idea to find out more about how it works.

6 Jul 2021

New genetic biobank could hold the key to preventing SIDS

A state-of-the-art genetic biobank could hold the key to preventing Sudden Infant Death Syndrome (SIDS), potentially saving the lives of hundreds of babies who die from the devastating condition each year.

5 Jul 2021

A new study reveals unintended CRISPR/Cas9 editing events

A recent study by researchers from Sweden and the United Kingdom shows that CRISPR/Cas9-based genomic engineering can prompt unwanted on-target effects, and highlights the complexity of human DNA repair mechanisms in the presence of the powerful prokaryotic Cas9 nuclease. The paper is currently available on the bioRxiv* preprint server.

4 Jul 2021

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Medical researchers led by Kyushu University have revealed a possible underlying genetic pathway behind the neurological dysfunction of Rett syndrome.

2 Jul 2021

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

Methylglyoxal (MG) is a highly reactive α-ketoaldehyde formed endogenously as a byproduct of the glycolytic pathway. MG accumulates under conditions of hyperglycemia, impaired glucose metabolism, or oxidative stress.

2 Jul 2021

DNA News and Research

Further Reading

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Uncovering cellular mechanism related to gene silencing therapies

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

Study explores the intersection of culture and health among Mexican women and children

Skin pigmentation mechanism confers major protection against UV-related cancers

New discovery provides clues to elucidate the pathogenesis of muscle diseases

NYUAD researchers unlock an epigenetic code that allows liver regeneration

Comprehensive genetic study provides new insights on cleft lip and palate

Researchers unravel mechanisms that produce individualized metabolism in leukemia

Brain cells snap DNA strands in numerous locations to make memories

New method expands view into activity of single cells

Castration of male sheep slows DNA aging

Study examines evolution and avidity of anti-SARS-CoV-2 IgG antibodies after mRNA vaccination

Developing a face mask that can detect COVID-19

New genetic biobank could hold the key to preventing SIDS

A new study reveals unintended CRISPR/Cas9 editing events

Researchers reveal underlying genetic pathway behind neurological dysfunction of Rett syndrome

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo