Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Researchers set up citizen science program to gain insight into triatomine insects in Texas

Chagas disease is caused by a parasitic protozoan (Trypanosoma cruzi) and transmitted via triatomine insects known locally in Texas as "kissing bugs". Due to the success of community based triatomine surveillance and collection in Central and South America, researchers from Texas A & M University set up a citizen science program to gain insight into the distribution and infection prevalence of triatomine insects in Texas.

11 Dec 2015

New heart failure drug may increase patients' risk of Alzheimer's disease, macular degeneration

Patients with mild heart failure stand to benefit from a new drug that can halt the progression of their disease and reduce their risk of cardiovascular-related death. But the drug -- a tablet that combines the agents valsartan and sacubitril, sold under the trade name Entresto by drugmaker Novartis -- may be too good to be true, according to Arthur M. Feldman, MD, PhD, Executive Dean of the Lewis Katz School of Medicine at Temple University, Chief Academic Officer of the Temple University Health System, and Laura H. Carnell Professor of Medicine at LKSOM.

10 Dec 2015

Ground breaking technology could revolutionise cancer diagnosis

A University of Warwick computer scientist is working with technology that could revolutionise how some cancers are diagnosed.

9 Dec 2015

Tetra begins human Phase 1 safety trials of BPN14770

Tetra Discovery Partners today announced that the company has initiated human Phase 1 safety trials of its lead compound BPN14770, which Tetra is developing as a potential treatment to both improve memory and slow the progression of Alzheimer's disease.

9 Dec 2015

Aspirin does not improve survival among breast cancer patients with aggressive disease

Whether aspirin may help prevent or reduce the risk of breast cancer remains a hotly debated research question. While past studies have indicated a potential benefit, most recently in hormone receptor-positive breast cancers, one new study from Penn Medicine suggests otherwise.

9 Dec 2015

New drug therapies that target glutamate pathway may be effective for subgroups of patient with schizophrenia

Mounting evidence indicates that disturbances in the brain's glutamate pathway contribute to symptoms of schizophrenia. Thus, the glutamate pathway has become the target of a number of new drug therapies. Findings published in the journal Biological Psychiatry suggest that at least one of these drugs may be an effective treatment for individuals in the early course of the illness.

9 Dec 2015

NeoGenomics introduces NeoLAB Solid Tumor Monitor, NeoLAB BTK Inhibitor Acquired Resistance test

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today an expansion of its liquid biopsy testing menu to include two new tests, a NeoLAB Solid Tumor Monitor and a NeoLAB BTK Inhibitor Acquired Resistance test.

8 Dec 2015

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Scientists have shown for the first time why loss of the enzyme CD73 in human cancer promotes tumor progression.

8 Dec 2015

Existing compound offers hope for slowing Huntington's disease progression

Currently, there is no treatment to halt the progression of Huntington's disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities. Now, researchers at University of California, San Diego School of Medicine have discovered that an existing compound, previously tested for diabetes, offers hope for slowing HD and its symptoms.

8 Dec 2015

Dompé’s investigational biotech molecule receives orphan drug designation for treatment of neurotrophic keratitis

The Dompé biopharmaceutical company announced today that the Committee for Orphan Medicinal Products of the European Medicines Agency (EMA) has officially designated recombinant human Nerve Growth Factor (rhNGF) - the investigational biotech molecule developed by Dompé based on research by Nobel Laureate Rita Levi Montalcini - as an orphan drug for the treatment of neurotrophic keratitis.

8 Dec 2015

Risk of dementia decreasing? An interview with Professor Carol Brayne, University of Cambridge

In this analysis we brought together the few European studies that have looked, within geographical areas, at the prevalence or incidence of dementia in the population aged 65 and over.

7 Dec 2015

Ibrutinib more effective than traditional chemotherapy in older untreated patients with CLL

A multi-center, international, randomized, Phase III study of older untreated patients with chronic lymphocytic leukemia (CLL) demonstrated that ibrutinib, a kinase inhibitor, is significantly more effective than traditional chemotherapy with chlorambucil.

7 Dec 2015

International telepathology consultations can improve patient care in China, study finds

International telepathology consultations can significantly improve patient care, according to a new study by UPMC and KingMed Diagnostics researchers. Their review of more than 1,500 pathology cases submitted electronically to UPMC over three years found that consultation with UPMC pathologists resulted in significantly altered treatment plans for more than half of the cases in which a patient's primary diagnosis had been provided from referring hospitals in China.

1 Dec 2015

Researchers discover drug target and genetic pathway for graft-versus-host disease

A Seattle Children's Research Institute lab has discovered a genetic pathway that can be targeted with existing drugs to prevent graft-versus-host disease (GVHD), a common and deadly complication of bone marrow transplants.

30 Nov 2015

Sectra provides Breast Imaging PACS to Kentucky Breast Care

International medical imaging IT company Sectra announces that Kentucky Breast Care has entered into a multi-year agreement to provide Breast Imaging PACS for their women's healthcare practice. This will allow Kentucky Breast Care to increase collaboration with sub-specialists around the US and offer exceptional care for their patients.

30 Nov 2015

Can-Fite BioPharma reports financial results, provides updates on drug development programs

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs being developed to treat inflammatory diseases, cancer and sexual dysfunction, today reported financial results for the nine months ended September 30, 2015 and updates on its drug development programs.

27 Nov 2015

Containing Airborne Contaminants

An interview with Gary Broomhead, discussing the potential sources of contamination in research and how controlling airflow in the laboratory can reduce this.

26 Nov 2015

TransLUMINAL-B project kicked off to study luminal breast cancers

Following a kick-off meeting, the TransLUMINAL-B project, which is being led by Charité -- Universitätsmedizin Berlin, is now officially underway. Over the next three years, researchers involved in the project will study the process of metastasis formation and the role of malignant cells, which accumulate in the blood and bone marrow of patients with certain types of breast cancer.

26 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

UNC study reveals how specific schizophrenia symptoms linked to distinct brain circuits

Schizophrenia, a severe mental disorder affecting about one in 100 people, is notoriously difficult to diagnose and treat, in large part because it manifests differently in different people. A new study published today in Molecular Neuropsychiatry helps explain why.

25 Nov 2015

Pathology News and Research

Further Reading

Researchers set up citizen science program to gain insight into triatomine insects in Texas

New heart failure drug may increase patients' risk of Alzheimer's disease, macular degeneration

Ground breaking technology could revolutionise cancer diagnosis

Tetra begins human Phase 1 safety trials of BPN14770

Aspirin does not improve survival among breast cancer patients with aggressive disease

New drug therapies that target glutamate pathway may be effective for subgroups of patient with schizophrenia

NeoGenomics introduces NeoLAB Solid Tumor Monitor, NeoLAB BTK Inhibitor Acquired Resistance test

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Existing compound offers hope for slowing Huntington's disease progression

Dompé’s investigational biotech molecule receives orphan drug designation for treatment of neurotrophic keratitis

Risk of dementia decreasing? An interview with Professor Carol Brayne, University of Cambridge

Ibrutinib more effective than traditional chemotherapy in older untreated patients with CLL

International telepathology consultations can improve patient care in China, study finds

Researchers discover drug target and genetic pathway for graft-versus-host disease

Sectra provides Breast Imaging PACS to Kentucky Breast Care

Can-Fite BioPharma reports financial results, provides updates on drug development programs

Containing Airborne Contaminants

TransLUMINAL-B project kicked off to study luminal breast cancers

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

UNC study reveals how specific schizophrenia symptoms linked to distinct brain circuits

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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