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World's first confirmed case of SARS-CoV-2 re-infection

A team of researchers at the University of Hong Kong said that they have proven that a 33-year-old man was infected by the SARS-CoV-2 virus for a second time. The man was discharged from a hospital in April but contracted the infection again after returning from Spain via the United Kingdom in August.

24 Aug 2020

Single dose nasal vaccine against SARS-CoV-2 shows promise in animal studies

Now researchers at the Washington University School of Medicine in St. Louis have worked on developing a candidate vaccine against the infection that could be administered in a single dose via a nasal spray rather than an injection. In their preliminary studies using lab mice, this single dose of the nasal vaccine successfully prevented the infection with the novel coronavirus.

24 Aug 2020

Raccoon dogs potential intermediate host for SARS-CoV-2

Researchers at the Friedrich Loeffler Institute in Germany have conducted a study demonstrating that raccoon dogs were a potential intermediate host in the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

23 Aug 2020

Genomic analysis reveals vulnerability of many animal species to SARS-CoV-2 infection

Humans are not the only species facing a potential threat from SARS-CoV-2, the novel coronavirus that causes COVID-19, according to a new study from the University of California, Davis.

21 Aug 2020

DNA nanoswitches may provide an inexpensive platform to rapidly detect emerging viruses

Programmable DNA nanoswitches that bind to viral RNA in human body fluids may provide an inexpensive platform to rapidly detect a wide variety of emerging viruses, including SARS-CoV-2, according to a new study.

21 Aug 2020

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

21 Aug 2020

Key molecule can be used to assess prognosis of triple negative breast cancer

Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer.

21 Aug 2020

Bioinformatics identifies key genes and cellular pathways in COVID-19

The COVID-19 pandemic is showing no signs of waning or extinction anytime soon. Now, a new study published on the preprint server bioRxiv* in August 2020 shows a new bioinformatics approach to studying the pathogenesis of this disease, by uncovering the differentially expressed genes (DEGs) and cell signaling pathways that cause the disease characteristics. This will help develop better therapies to counter the effects of these genes.

20 Aug 2020

Lack of consistency in COVID-19-related data could harm prevention efforts

Since COVID-19 emerged late last year, there's been an enormous amount of research produced on this novel coronavirus disease.

20 Aug 2020

Air pollution may play a role in development of cardiometabolic diseases, shows study

Air pollution is the world's leading environmental risk factor, and causes more than nine million deaths per year.

20 Aug 2020

Study shows why certain genetically predisposed individuals do not develop heart disease

Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can lead to elevated cholesterol and increased risk for a premature heart attack.

20 Aug 2020

Study indicates a potential link between Alzheimer's and common brain disorder

Alzheimer's disease is one of the most common causes of dementia, and while most people might know someone who is affected by it, the genetic factors behind the disease are less known.

20 Aug 2020

Genomics study shows multiple and diverse SARS-CoV-2 introductions in the US capital region

A recent study led by the researchers from Johns Hopkins University reveals multiple and diverse introductions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the United States National Capital Region during the initial phase of coronavirus disease 2019 (COVID-19) pandemic. The study is currently available on the medRxiv* preprint server.

19 Aug 2020

New database could speed the development of gene-targeted therapies for breast cancer

All current breast cancer drugs were first tested in cell lines. Each cell line began as cancer in a patient. As such, each cell line is a surrogate for that patient's disease.

19 Aug 2020

Study sheds light on 500-year old mystery about the human heart

Researchers have investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart. The study, published in the journal Nature, sheds light on questions asked by Leonardo da Vinci 500 years ago, and shows how the shape of these muscles impacts heart performance and heart failure.

19 Aug 2020

Study shows how bacteria become increasingly infectious under certain conditions

Bacteria that invade animal cells in order to multiply are widespread in nature. Some of these are pathogens of humans and animals. In the environment, they are often found inside unicellular organisms.

18 Aug 2020

Study shows how foodborne pathogen infects a human intestinal cell

As soon as the foodborne pathogen Vibrio parahaemolyticus infects a human intestinal cell, the bacteria are already planning their escape.

18 Aug 2020

Study shows why young, female patients have low response rates to cancer immunotherapy

Cancer immunotherapy -- empowering a patient's own immune system to clear away tumors on its own -- holds great promise for some patients. But for other patients, immunotherapy just doesn't work.

18 Aug 2020

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.

17 Aug 2020

Deciphering the largest CRISPR system

Professor Guillermo Montoya spoke to News-Medical on his research that involved visualizing the largest and most complex CRISPR system.

17 Aug 2020

Genome News and Research

World's first confirmed case of SARS-CoV-2 re-infection

Single dose nasal vaccine against SARS-CoV-2 shows promise in animal studies

Raccoon dogs potential intermediate host for SARS-CoV-2

Genomic analysis reveals vulnerability of many animal species to SARS-CoV-2 infection

DNA nanoswitches may provide an inexpensive platform to rapidly detect emerging viruses

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

Key molecule can be used to assess prognosis of triple negative breast cancer

Bioinformatics identifies key genes and cellular pathways in COVID-19

Lack of consistency in COVID-19-related data could harm prevention efforts

Air pollution may play a role in development of cardiometabolic diseases, shows study

Study shows why certain genetically predisposed individuals do not develop heart disease

Study indicates a potential link between Alzheimer's and common brain disorder

Genomics study shows multiple and diverse SARS-CoV-2 introductions in the US capital region

New database could speed the development of gene-targeted therapies for breast cancer

Study sheds light on 500-year old mystery about the human heart

Study shows how bacteria become increasingly infectious under certain conditions

Study shows how foodborne pathogen infects a human intestinal cell

Study shows why young, female patients have low response rates to cancer immunotherapy

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

Deciphering the largest CRISPR system

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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