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Gene expression is rhythmic in most tissue types

Researchers have mapped primate gene expression throughout the day and discovered that the majority of critical gene activity is time dependent, which may aid the development of new treatments for many diseases.

9 Feb 2018

Cholesterol and other lipids in the blood play role in many diseases

Lipids are fatty molecules that play important signaling and storage roles in the body, but having an excess of some lipids, like cholesterol, is a risk factor for many metabolic diseases.

8 Feb 2018

Biomedical engineers develop miniature self-sealing wound model

Biomedical engineers have developed a miniature self-sealing model system for studying bleeding and the clotting of wounds. The researchers envision the device as a drug discovery platform and potential diagnostic tool.

8 Feb 2018

Researchers describe human blood-nerve barrier transcriptome for the first time

Human peripheral nerves -- all the nerves outside of the central nervous system -- are protected by the blood-nerve barrier. This is a tight covering of endothelial cells that maintains the microenvironment within the nerves by restricting the amounts or types of water, ions, solutes and nutrients that can reach the axons, or electric cables within the nerves, from the blood circulation system.

8 Feb 2018

Researchers test effectiveness of investigational drug in treating diastolic dysfunction of the heart

Researchers at the University of Colorado School of Medicine have identified a potential treatment target for patients with a common type of heart failure.

8 Feb 2018

Dietary protein supplements provide muscle mass and strength gains for weight lifters

The debate is over. Dietary protein supplements significantly improve muscle strength and size when taken by healthy adults who lift weights, a determination reached by McMaster scientists who analyzed dozens of research studies.

8 Feb 2018

Research could pave way for treatments to reduce risk of heart disease and stroke

The discovery of a previously unknown interaction between proteins could provide a breakthrough in the prevention of damage to healthy blood vessels.

7 Feb 2018

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Scientists have for the first time discovered a mechanism that limits the number of "cellular janitors" in the nervous system, leading to increased risk for two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia, according to a Keck School of Medicine of USC study published today in Nature Medicine.

7 Feb 2018

Loss of coenzyme Q10 increases pre-diabetes risk

Levels of CoQ and the presence of insulin resistance were analyzed in a range of experimental laboratory settings, mouse models and samples from humans, as part of an ambitious research collaboration conducted with the University of Sydney, Victor Chang Cardiac Research Institute, Duke University School of Medicine, Garvan Institute of Medical Research, Genentech Inc. and the University of New South Wales.

7 Feb 2018

Open Pharma drug discovery project aims to develop new treatments for mycetoma

The MycetOS project was launched today by the University of Sydney, Erasmus MC, and the Drugs for Neglected Diseases initiative to use an Open Pharma approach to discover compounds that could lead to new treatments for patients suffering from fungal mycetoma (eumycetoma), a devastating disease for which current treatments are ineffective, expensive, and toxic.

6 Feb 2018

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's DNA, according to a study from UT Southwestern Medical Center.

6 Feb 2018

CHLA participates in clinical trial using stem cells to treat rare congenital heart defect

Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart.

5 Feb 2018

Study shows link between regular physical exercise and better lung function among smokers

Leisure-time vigorous physical activity is associated with better lung function among current smokers. This is the main conclusion of a new study published in Thorax and led by researchers from the Barcelona Institute of Global Health, an institution supported by "la Caixa" Foundation.

5 Feb 2018

Researchers discover gene network that regulates the motor neuron development in growing embryo

UCLA researchers have discovered the inner workings of a gene network that regulates the development of spinal motor neurons in the growing chicken and mouse embryo.

2 Feb 2018

Study finds low muscle strength as early risk factor for ALS

Low muscle strength during the later teen years has been identified as a risk factor for much later onset of the neurological disease known as ALS, or amyotrophic lateral sclerosis. A study at Sahlgrenska Academy published in the Journal of Neurology also links low blood counts at a young age to ALS.

2 Feb 2018

Study investigates impact of crash diet on heart function

Crash diets can cause a transient deterioration in heart function, according to research presented today at CMR 2018.

2 Feb 2018

Breast cancer patients may be at increased risk of cardiovascular diseases

Breast cancer patients may be at an increased risk of cardiovascular diseases including heart failure and may benefit from a treatment approach that weighs the benefits of specific therapies against potential damage to the heart, according to a new scientific statement from the American Heart Association published in its journal Circulation.

1 Feb 2018

Muscle News and Research

Gene expression is rhythmic in most tissue types

Cholesterol and other lipids in the blood play role in many diseases

Biomedical engineers develop miniature self-sealing wound model

Researchers describe human blood-nerve barrier transcriptome for the first time

Researchers test effectiveness of investigational drug in treating diastolic dysfunction of the heart

Dietary protein supplements provide muscle mass and strength gains for weight lifters

Research could pave way for treatments to reduce risk of heart disease and stroke

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Loss of coenzyme Q10 increases pre-diabetes risk

Open Pharma drug discovery project aims to develop new treatments for mycetoma

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

CHLA participates in clinical trial using stem cells to treat rare congenital heart defect

Study shows link between regular physical exercise and better lung function among smokers

Researchers discover gene network that regulates the motor neuron development in growing embryo

Study finds low muscle strength as early risk factor for ALS

Study investigates impact of crash diet on heart function

Breast cancer patients may be at increased risk of cardiovascular diseases

Standing for long periods of time could aid weight loss, finds study

As states target high drug prices, pharma targets state lawmakers

Discovery of molecular nets may lead to new treatment approach for heart failure

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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