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Researchers identify a key regulator that stops excessive inflammation

A component has been identified by researchers in Umeå as a novel regulator of the immune system. It acts as a molecular switch to deactivate the innate immune system and has the ability to prevent certain diseases caused by an excessive activation of the immune system.

15 Jan 2019

Researchers manipulate T cells to improve transplant success

Researchers have manipulated T cells in a way that prevents the rejection of transplanted organs, without affecting the immune system’s ability to fight microbial infection.

15 Jan 2019

DNA origami can accurately measure how antibodies interact with several antigens

Using DNA origami - DNA-based design of precise nanostructures - scientists at Karolinska Institutet in collaboration with researchers at University of Oslo, have been able to demonstrate the most accurate distance between densely packed antigens in order to get the strongest bond to antibodies in the immune system.

14 Jan 2019

Meth’s resurgence spotlights lack of meds to combat the addiction

In 2016, news reports warned the public of an opioid epidemic gripping the nation. But Madeline Vaughn, then a lead clinical intake coordinator at the Houston-based addiction treatment organization Council on Recovery, sensed something different was going on with the patients she checked in from the street.

14 Jan 2019

Novel microfluidic device for real-time detection of cholesterol in liver-on-chip cultures

In a paper to be published in the September/December 2019 issue of TECHNOLOGY, a team of researchers from the Department of Biomedical Engineering at Illinois Institute of Technology, Chicago has developed a novel microfluidic device for measuring in real-time the cholesterol secreted from liver tissue-chip containing human hepatocytes.

11 Jan 2019

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

In nature, certain molecules with the same chemical composition, can exist in two different shapes that are mirrors images of each other, much like our hands.

11 Jan 2019

Expression of a molecule in blood cells inversely predicts appearance of subclinical atherosclerosis

Earlier detection of cardiovascular disease is a step closer thanks to the findings of a research team at the Centro Nacional de Investigaciones Cardiovasculares led by Francisco Sánchez-Madrid and Pilar Martín.

10 Jan 2019

Scientists pinpoint a hidden culprit in heart failure

An international research team led by scientists at the University of Alberta have pinpointed a hidden culprit that leads to dilated cardiomyopathy--a dangerous condition that accounts for 20 per cent of all cases of heart failure--which opens the door to potential new treatments that could help counter the threat.

10 Jan 2019

Novel biomarker links tumor progression to genome instability

Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and the food we eat.

10 Jan 2019

Unusual molecular regulatory mechanism discovered in unicellular parasites

Researchers of the University of Bern have discovered a new molecular regulatory mechanism in unicellular parasites which has never before been observed.

10 Jan 2019

Aptamer Group and AstraZeneca to develop new drug delivery vehicles

Aptamer Group today announced it has signed an agreement with AstraZeneca to explore the potential of using aptamer technology to target the kidney.

From AstraZeneca 10 Jan 2019

Drug development options diversified with new manganese catalyst

A University of Illinois team of researchers led by chemistry professor M. Christina White has developed a new manganese-based catalyst that can change the structure of druglike molecules to make new drugs, advancing the pace and efficiency of drug development.

9 Jan 2019

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Millions of people suffer from inflammatory bowel disease worldwide, either in the form of ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD.

9 Jan 2019

Developmental dysfunction of prefrontal cortex causes cognitive deficits related to mental illness

Faulty wiring of the prefrontal cortex during development leads to abnormal brain activity and cognitive impairments related to mental illness, according to a mouse study published in JNeurosci.

From Society for Neuroscience 9 Jan 2019

Researchers identify and overcome barrier in CRISPR gene editing to treat muscular dystrophy

The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be used to effectively treat long-term, chronic conditions.

9 Jan 2019

Moderate amounts of healthy fats could soon be allowed in diets

Most public health guidelines including the Dietary Guidelines for Americans do not allow fat portions in excess. However nutritionists and dieticians have now agreed that not all fats in diet are bad and many of them could be allowed.

8 Jan 2019

Study offers new insight on mechanism underlying control of gene expression

Researchers have provided new insight on the mechanism underlying the control of gene expression in all living organisms, according to a study published today in eLife.

8 Jan 2019

New molecular engineering method improves precision of biomarker analysis

Researchers from the University of Helsinki in cooperation with the University of Tartu, Competence Centre on Health Technologies from Estonia, and the Karolinska Institute, published an article in Nature's partner journal Genomic Medicine in which they present Targeted Allele Counting by sequencing along with several of its potential applications.

8 Jan 2019

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Researchers from LSTM and the University of Liverpool have successfully optimized a hit from a whole cell screening of a 10000-compound library to deliver the first novel fully synthetic and rationally designed anti-Wolbachia drug, AWZ1066S, which could potentially be used to treat onchocerciasis and lymphatic filariasis.

8 Jan 2019

Washington University scientists find an unknown route for cellular fuel delivery

Scientists at Washington University School of Medicine in St. Louis have identified a previously unknown route for cellular fuel delivery, a finding that could shed light on the process of aging and the chronic diseases that often accompany it.

8 Jan 2019

Molecule News and Research

Researchers identify a key regulator that stops excessive inflammation

Researchers manipulate T cells to improve transplant success

DNA origami can accurately measure how antibodies interact with several antigens

Meth’s resurgence spotlights lack of meds to combat the addiction

Novel microfluidic device for real-time detection of cholesterol in liver-on-chip cultures

Steady-state CD spectroscopy is a major structural tool in (bio)chemical analysis

Expression of a molecule in blood cells inversely predicts appearance of subclinical atherosclerosis

Scientists pinpoint a hidden culprit in heart failure

Novel biomarker links tumor progression to genome instability

Unusual molecular regulatory mechanism discovered in unicellular parasites

Aptamer Group and AstraZeneca to develop new drug delivery vehicles

Drug development options diversified with new manganese catalyst

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Developmental dysfunction of prefrontal cortex causes cognitive deficits related to mental illness

Researchers identify and overcome barrier in CRISPR gene editing to treat muscular dystrophy

Moderate amounts of healthy fats could soon be allowed in diets

Study offers new insight on mechanism underlying control of gene expression

New molecular engineering method improves precision of biomarker analysis

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Washington University scientists find an unknown route for cellular fuel delivery

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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