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Difficult transmembrane protein targets for therapeutic antibodies

In this interview, News-Medical talks to Sylvia Xie, product scientist at Sino Biological, about the ongoing emergence of transmembrane proteins as targets for therapeutic antibodies.

From Sino Biological Inc. 12 Jul 2023

Adiponectin can be a potential therapeutic target for obesity and diabetes

Adiponectin, a hormone secreted by adipose tissue, plays a doubly important role in preserving pancreatic function: in lean people, it protects beta cells, which make insulin, and in obese people, it reverses damage to fatty tissue.

11 Jul 2023

Chemotherapy-induced changes to gut bacteria linked to unhealthy weight gain in breast cancer patients

Researchers have found a link between chemotherapy-induced changes to gut bacteria and the unhealthy weight gain seen in breast cancer patients, pointing the way to potentially help survivors avoid obesity-related illness later in their lives.

11 Jul 2023

Rethinking how cancer immunotherapy drugs are delivered could save millions

A new analysis finds that up to millions of dollars could be saved annually on cancer immunotherapy treatments across the Veterans Health Administration by reconsidering how those drugs are delivered.

11 Jul 2023

THC-O-acetate's psychedelic effects may be greatly exaggerated

The cannabis plant is complex, with about 100 cannabinoids, or compounds, many of which science still knows little or nothing about.

11 Jul 2023

£1.5 million funding boost awarded for revolutionary test to improve early detection of Alzheimer's

A significant NIHR grant will enable researchers at the universities of Bath and Bristol, in collaboration with Cumulus Neuroscience, to develop revolutionary technology to help expand early dementia diagnosis.

11 Jul 2023

Using technological solutions to treat mental illnesses

The Center for Responsible Research and Innovation (CeRRi) within the Fraunhofer Institute for Industrial Engineering IAO, working with the University of Ottawa in Canada, the National Paraplegic Hospital in Toledo, Spain and the University Medical Center Göttingen in Germany, has developed recommended actions for implementing technological solutions to treat mental illnesses.

11 Jul 2023

AGS supports CMS decision to require registry data for monoclonal antibodies for Alzheimer's disease

The American Geriatrics Society (AGS) supports the recently announced decision from the Centers for Medicare and Medicaid Services (CMS) to require the collection of real-world information via a registry to study monoclonal antibodies directed against amyloid for the treatment of Alzheimer's disease.

11 Jul 2023

Prescription stimulants safe for treating ADHD, study finds

Many parents whose kids take prescription stimulants like Ritalin to treat ADHD worry that it could lead to illicit drug use later.

11 Jul 2023

Vernal Biosciences Announces Partnership With REPROCELL

Vernal Biosciences, a leader in mRNA and LNP manufacturing, and REPROCELL Inc., Japan’s first induced pluripotent stem cell (iPSC) company, have partnered to provide mRNA services in Japan at scale for research and clinical applications.

From REPROCELL 11 Jul 2023

Muscle soothes mind: Exercise training can lower stress-related blood pressure responses

Researchers performed a meta-analysis to elucidate the effects of exercise training on stress-related blood pressure reactivity.

11 Jul 2023

Researchers identify glycolipid that blocks infection with SARS-CoV-2 and RSV

7DW8-5, a glycolipid that utilizes the body's non-specific immune response to quickly combat viral infections, including COVID-19 in vivo.

11 Jul 2023

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

With support from Amplicore, a University of Cincinnati spinoff biopharmaceutical company, researchers at UC have begun a Department of Defense-funded clinical trial that seeks a regenerative pharmaceutical solution for meniscal tears.

10 Jul 2023

New drug shows synergistic effect with antifungals in killing drug-resistant fungi

A study conducted at the University of São Paulo (USP) in Brazil shows that brilacidin, a new drug tested for treatment of diseases ranging from bacterial skin infections to COVID-19, can kill drug-resistant strains of fungi when combined with two classes of antifungals available on the market.

10 Jul 2023

Surprising ancestry of caterpillar venom could be key to delivery of lifesaving drugs

Researchers at The University of Queensland have discovered the venom of a notorious caterpillar has a surprising ancestry and could be key to the delivery of lifesaving drugs.

10 Jul 2023

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, promote standardization of testing across different laboratories, and improve patient care.

10 Jul 2023

Study: Flavor restrictions could make major progress in fighting youth vaping epidemic

Major progress could be made in fighting the youth vaping epidemic with a complete restriction on sweet flavorings and cooling agents in both cartridge and disposable e-cigarette devices, according to a new study from the Center for Tobacco Research at The Ohio State University Comprehensive Cancer Center.

10 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

UVA researchers discover how 'hair cells' repair themselves

University of Virginia School of Medicine researchers have discovered how the cells that let us hear can repair themselves after being damaged.

10 Jul 2023

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Researchers investigated the role of senescent cells in the context of SARS-CoV-2 infection.

10 Jul 2023

Drugs News and Research

Difficult transmembrane protein targets for therapeutic antibodies

Adiponectin can be a potential therapeutic target for obesity and diabetes

Chemotherapy-induced changes to gut bacteria linked to unhealthy weight gain in breast cancer patients

Rethinking how cancer immunotherapy drugs are delivered could save millions

THC-O-acetate's psychedelic effects may be greatly exaggerated

£1.5 million funding boost awarded for revolutionary test to improve early detection of Alzheimer's

Using technological solutions to treat mental illnesses

AGS supports CMS decision to require registry data for monoclonal antibodies for Alzheimer's disease

Prescription stimulants safe for treating ADHD, study finds

Vernal Biosciences Announces Partnership With REPROCELL

Muscle soothes mind: Exercise training can lower stress-related blood pressure responses

Researchers identify glycolipid that blocks infection with SARS-CoV-2 and RSV

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

New drug shows synergistic effect with antifungals in killing drug-resistant fungi

Surprising ancestry of caterpillar venom could be key to delivery of lifesaving drugs

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

Study: Flavor restrictions could make major progress in fighting youth vaping epidemic

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

UVA researchers discover how 'hair cells' repair themselves

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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