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New drug data release set to power genetic research into cancer treatment

This week (25 July) the Genomics of Drug Sensitivity in Cancer project has released the results of four years of intense data gathering and exploration which will power genetic research into cancer treatment worldwide.

26 Jul 2019

New biomimetic culture system enables more extensive testing of drugs and gene therapies

Researchers at the University of Louisville have developed an easily reproducible system that enables them to keep slices of human hearts alive for a longer period of time, allowing more extensive testing of new drugs and gene therapies.

26 Jul 2019

Novel therapeutic strategy for treating Lafora Disease shows promise in preclinical study

A team of scientists have designed and tested in mice a novel and promising therapeutic strategy for treating Lafora Disease, a fatal form of childhood epilepsy.

25 Jul 2019

Researchers receive $10 million grant to examine opioid addiction treatment for jail detainees

Researchers at the University of Massachusetts Amherst and the University of Massachusetts Medical School are among the scientists at a dozen institutions nationwide that will form the Justice Community Opioid Innovation Network, an ambitious, $155 million effort to improve opioid addiction treatment in criminal justice settings, the National Institutes of Health announced.

25 Jul 2019

Common antimalarial treatment has less effect in children with severe malnutrition

Researchers have found that severe malnutrition is associated with lower exposure to the antimalarial drug lumefantrine in children treated with artemether-lumefantrine, the most common treatment, for uncomplicated falciparum malaria.

24 Jul 2019

Alzheimer's Association awards $3 million grant to support Longeveron's innovative clinical trial

The Alzheimer's Association has awarded Longeveron LLC, a Miami-based biopharmaceutical company that develops cellular therapies for aging-related diseases, a $3 million grant to be applied to the company's mesenchymal stem cell Alzheimer's research.

23 Jul 2019

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Herbs, including cilantro, have a long history of use as folk medicine anticonvulsants. Until now, many of the underlying mechanisms of how the herbs worked remained unknown.

23 Jul 2019

Scientists identify new way to target bottleneck for cancer cell growth

The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. Scientists at Winship Cancer Institute of Emory University have identified a way of targeting ribonucleotide reductase that may avoid the toxicity of previous approaches, informing focused drug discovery efforts.

23 Jul 2019

FNR funds an additional 6 million euros for Luxembourg Parkinson's study

In spring 2015, the National Centre for Excellence in Research on Parkinson's Disease was created as the very first inter-institutional research program of its kind in Luxembourg.

22 Jul 2019

Microbial compound found in infant gut increases allergy, asthma risk

A study of newborn infants has identified a compound produced by gut bacteria that appears to predispose certain infants to allergies and asthma later in life.

22 Jul 2019

Servier chooses Pall as single-source supplier for new biomanufacturing facility

Pall Corporation, a global leader in filtration, separation and purification, has been chosen by Servier, an independent international pharmaceutical company, as an exclusive technology and services provider for their Gidy, France biomanufacturing facility.

From Pall Corporation 22 Jul 2019

Using zebrafish to discover and identify new drugs to treat spinal cord lesions

A research team led by Leonor Saúde, Principal Investigator at Instituto de Medicina Molecular, in partnership with the company Technophage, SA, has designed a simple and efficient platform that uses zebrafish to discover and identify new drugs to treat spinal cord lesions.

22 Jul 2019

Don't Miss the Blood-Brain Barrier Drug Delivery (B3DD) Summit this August

The B3DD Summit will be held in Boston from August 13-15, 2019. This news story provides an overview of what you can expect at this year's conference.

From Blood-Brain Barrier Delivery Summit (B3DD) 17 Jul 2019

Rutgers researchers create new device to see if targeted cancer therapy is working

Rutgers researchers have created a device that can determine whether targeted chemotherapy drugs are working on individual cancer patients.

17 Jul 2019

AI-enabled device detects if targeted chemotherapy is working

A new portable device that utilizes artificial intelligence (AI) and biosensors can rapidly detect if cancer cells thrive after chemotherapy treatment.

17 Jul 2019

Antioxidant precursor molecule could improve dopamine levels in Parkinson's patients

N-acetylcysteine (NAC) is a naturally occurring molecule that replenishes one of the body's antioxidants and now shows potential benefit as part of a standard course of treatment for patients with Parkinson's disease, according to a study published in the journal, Clinical Pharmacology & Therapeutics.

16 Jul 2019

Gene modulation goes wireless hacking the "boss gene"

Researchers from the University at Buffalo have successfully used technology to wirelessly tweak the functioning of a gene FGFR1. This gene is vital in the growth of embryos into adults. Their experiments were successful in the lab grown brain tissues and shows potential in therapeutics.

16 Jul 2019

New method spots rare immune cells reactive against cancer

Researchers from the Garvan Institute of Medical Research have developed a new method to spot rare immune cells that are reactive against cancer cells, from within a patient's own immune system.

16 Jul 2019

Removing bacterial armor could be new way to fight anthrax

A new study led by Dr. Antonella Fioravanti in the lab of Prof. Han Remaut (VIB-VUB Center for Structural Biology) has shown that removing the armor of the bacterium that causes anthrax slows its growth and negatively affects its ability to cause disease.

16 Jul 2019

Loose double-stranded RNA molecules spur skin rejuvenation

Want to smooth out your wrinkles, erase scars and sunspots, and look years younger? Millions of Americans a year turn to lasers and prescription drugs to rejuvenate their skin, but exactly how that rejuvenation works has never been fully explained.

From Johns Hopkins Medicine 16 Jul 2019

Therapeutics News and Research

New drug data release set to power genetic research into cancer treatment

New biomimetic culture system enables more extensive testing of drugs and gene therapies

Novel therapeutic strategy for treating Lafora Disease shows promise in preclinical study

Researchers receive $10 million grant to examine opioid addiction treatment for jail detainees

Common antimalarial treatment has less effect in children with severe malnutrition

Alzheimer's Association awards $3 million grant to support Longeveron's innovative clinical trial

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Scientists identify new way to target bottleneck for cancer cell growth

FNR funds an additional 6 million euros for Luxembourg Parkinson's study

Microbial compound found in infant gut increases allergy, asthma risk

Servier chooses Pall as single-source supplier for new biomanufacturing facility

Using zebrafish to discover and identify new drugs to treat spinal cord lesions

Don't Miss the Blood-Brain Barrier Drug Delivery (B3DD) Summit this August

Rutgers researchers create new device to see if targeted cancer therapy is working

AI-enabled device detects if targeted chemotherapy is working

Antioxidant precursor molecule could improve dopamine levels in Parkinson's patients

Gene modulation goes wireless hacking the "boss gene"

New method spots rare immune cells reactive against cancer

Removing bacterial armor could be new way to fight anthrax

Loose double-stranded RNA molecules spur skin rejuvenation

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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