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EBV viral genome alters the host epigenetic landscape to drive stomach cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

27 Jul 2020

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

In a recent bioRxiv* study, UK researchers used interleukin modules to investigate the pathology of coronavirus disease (COVID-19).

27 Jul 2020

Researchers discover new method to treat herpes viruses

Researchers at Lund University in Sweden have discovered a new method to treat human herpes viruses. The new broad-spectrum method targets physical properties in the genome of the virus rather than viral proteins, which have previously been targeted.

24 Jul 2020

Neurotransmitter-derived lipidoids help carry drugs across the blood-brain barrier in mice

Biomedical engineers at the Tufts University School of Engineering have developed tiny lipid-based nanoparticles that incorporate neurotranmitters to help carry drugs, large molecules, and even gene editing proteins across the blood-brain barrier and into the brain in mice.

24 Jul 2020

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

Olympus, a leading manufacturer of high-end research microscopes, and Cytosurge, a precision manufacturer of cell manipulation technologies, have entered a co-marketing agreement to become a complete system provider to the scientific community’s growing need for next-generation single-cell and CRISPR genetic manipulation solutions.

From Evident Corporation - Life Sciences 24 Jul 2020

New genome-editing technologies can help understand disease-associated genetic mutations

New genome-editing technologies developed by researchers in J. Keith Joung's laboratory at the Massachusetts General Hospital (MGH) have the potential to help understand disease-associated genetic mutations that are based on C-to-G (cytosine to guanine) single base changes.

24 Jul 2020

Epigenomic modifications play key role in the development of lung tumors

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

23 Jul 2020

New strategy allows long-term, non-invasive tracking of cardiomyocytes

A new platform reported on today in STEM CELLS Translational Medicine (SCTM) will enable long-term tracking of cardiomyocytes produced from induced pluripotent stem cells (iPSCs) after implantation into the heart.

23 Jul 2020

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

In a new bioRxiv study, authors identified a isoform of ACE2 (designated as deltaACE2 or dACE2) receptor, shown to be induced in various human cell types.

23 Jul 2020

Amyloid plaques may act as trigger for Alzheimer's disease

The brains of people living with Alzheimer's are riddled with plaques: protein aggregates consisting mainly of amyloid-beta.

23 Jul 2020

Ashion Analytics and Elevation Oncology form innovative cancer treatment partnership

Ashion Analytics LLC today announced a partnership with Elevation Oncology, a clinical stage biopharmaceutical company, focused on the matching of patients with tumors harboring an NRG1 gene fusion identified using Ashion's proprietary GEM ExTra test with CRESTONE, a registration-directed Phase 2 study sponsored by Elevation Oncology.

23 Jul 2020

Vesigen Therapeutics to develop and commercialize novel drug-delivery technologies

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

New method can detect cancer cells in the abdominal cavity in real time

A research team from Tel Aviv University's Zimin Institute for Engineering Solutions Advancing Better Lives, led by Prof. Noam Shomron and doctoral student Artem Danilevsky, has developed a method to detect cancer cells in the abdominal cavity in real time.

22 Jul 2020

Experts use genomic analysis tools to create personalized treatment for kidney cancer patients

Experts at City of Hope and the Translational Genomics Research Institute are using one of the world's most comprehensive genomic analysis tools to map out personalized treatment plans for metastatic kidney cancer patients.

22 Jul 2020

New pathways that could help treat RNA viruses identified

Researchers at the University of New Hampshire have identified new pathways in an RNA-based virus where inhibitors, like medical treatments, unbind.

22 Jul 2020

IBBL and LNS launch MIRABANK in Luxembourg

The Laboratoire national de santé and the Integrated Biobank of Luxembourg have launched MIRABANK.

22 Jul 2020

Novel genetic measure could improve osteoporosis screening

An international team of scientists has developed a novel genetic measure that could dramatically improve how doctors assess the risk of sustaining a fracture due to osteoporosis or fragility.

21 Jul 2020

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.

21 Jul 2020

Analysis of the SARS-CoV-2 proteome via visual tools

Now, a new study published on the preprint server bioRxiv* in July 2020 shows how this can be advanced at a greater speed by combining experimental results with homology models obtained by high-throughput pipelines. This will help produce new hypotheses that will show novel druggable targets for effective drug development.

21 Jul 2020

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses, the large class of viruses that includes coronaviruses and many other pathogens.

20 Jul 2020

Genome News and Research

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

Study reveals manifold applications of cytokine transcriptional response modules in COVID-19

Researchers discover new method to treat herpes viruses

Neurotransmitter-derived lipidoids help carry drugs across the blood-brain barrier in mice

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

New genome-editing technologies can help understand disease-associated genetic mutations

Epigenomic modifications play key role in the development of lung tumors

New strategy allows long-term, non-invasive tracking of cardiomyocytes

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

Amyloid plaques may act as trigger for Alzheimer's disease

Ashion Analytics and Elevation Oncology form innovative cancer treatment partnership

Vesigen Therapeutics to develop and commercialize novel drug-delivery technologies

New method can detect cancer cells in the abdominal cavity in real time

Experts use genomic analysis tools to create personalized treatment for kidney cancer patients

New pathways that could help treat RNA viruses identified

IBBL and LNS launch MIRABANK in Luxembourg

Novel genetic measure could improve osteoporosis screening

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

Analysis of the SARS-CoV-2 proteome via visual tools

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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