Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Johns Hopkins scientists discover earliest premalignant genetic changes that mark potential onset of lung cancer

Working with tissue, blood and DNA from six people with precancerous and cancerous lung lesions, a team of Johns Hopkins scientists has identified what it believes are among the very earliest “premalignant” genetic changes that mark the potential onset of the most common and deadliest form of disease.

23 Sep 2015

UF researchers create fungi database to promote healthier environments

University of Florida Assistant Professor Matthew E. Smith is readying millions of fungi specimens for their close-ups. He and members of his team are helping to take photographs of and catalogue 2.3 million microfungi specimens for a worldwide database of mushrooms, truffles, molds and mildews, among other types of fungi.

23 Sep 2015

Salsalate drug offers new hope for treating Alzheimer's disease and FTD

Scientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau-related dysfunction in an animal model of frontotemporal dementia (FTD). Salsalate prevented the accumulation of tau in the brain and protected against cognitive impairments resembling impairments seen in Alzheimer's disease and FTD.

21 Sep 2015

Hypertension drugs block proteins that cause inflammation after traumatic brain injury

A new animal study shows that traumatic brain injury (TBI) affects the body as well as the brain and that treatment with hypertension drugs blocks the production of proteins related to inflammation.

21 Sep 2015

New study reshapes how scientists look at dengue virus

A new study is reshaping how scientists look at and understand a deadly virus. An international consortium of scientists, including researchers from the University of Texas Medical Branch at Galveston, worked to map out the antigenic differences in various strains of dengue virus.

19 Sep 2015

Genetically engineered vaccine eradicates precancerous cervical lesions

Scientists have used a genetically engineered vaccine to successfully eradicate high-grade precancerous cervical lesions in nearly one-half of women who received the vaccine in a clinical trial. The goal, say the scientists, was to find nonsurgical ways to treat precancerous lesions caused by HPV.

18 Sep 2015

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Cancer medicine is moving towards understanding what drives each particular patient's cancer. But not every patient has had access to this level of individualized care.

18 Sep 2015

UCI agrees to use MAggPI's web-based digital whole slide imaging to teach medical students

The University of California, Irvine School of Medicine has agreed to use web-based digital whole slide imaging developed by MAggPI in the teaching of medical students. In this collaboration, diagnostic-quality, expert-curated digital images of normal and diseased tissue will be incorporated in the teaching of histology and pathology to medical students at UCI.

16 Sep 2015

Using integrated molecular pathology to manage incidental pancreatic cysts: an interview with Dr Ananya Das

Pancreatic cystic neoplasms, or PCNs, are a subset of all pancreatic cysts that are found on the pancreas. PCNs are neoplastic cysts that span a biological spectrum from benign to malignant.

15 Sep 2015

Study reveals how leukemia cells evade deadly effects of BRD4 inhibitors

BRD4 inhibitors are among the most promising new agents in cancer therapy that are currently evaluated in clinical trials.

15 Sep 2015

Three-drug strategy effective against drug-resistant staph infection, finds new research

Three antibiotics that, individually, are not effective against a drug-resistant staph infection can kill the deadly pathogen when combined as a trio, according to new research.

15 Sep 2015

Two St. Louis institutions collaborate to create Center for Clinical Pharmacology

St. Louis College of Pharmacy and Washington University School of Medicine in St. Louis are joining forces to find better, safer and more effective ways to use prescription medications to improve health. Researchers from the two institutions are collaborating to create the Center for Clinical Pharmacology.

14 Sep 2015

Penn Medicine researchers show that DNA editing errors can lead to cancer

Sometimes when the immune system makes small mistakes, the body amplifies its response in a big way: Editing errors in the DNA of developing T and B cells can cause blood cancers. Now, researchers from the Perelman School of Medicine, University of Pennsylvania have shown that when the enzyme key to cutting and pasting segments of DNA hits so-called "off-target" spots on a chromosome, the development of immune cells can lead to cancer in animal models.

11 Sep 2015

Chronic alcohol consumption disrupts liver molecular circadian clock, leads to alcoholic liver disease

The activity of an organ in the body changes through the day and is governed by its internal clock, also known as a circadian clock. Staying on a circadian schedule is important for health, and disruptions lead to disease.

11 Sep 2015

Signs of Alzheimer’s found in growth hormone patients

People may be able to contract Alzheimer’s disease during certain medical procedures in the same way that Creutzfeldt-Jakob disease (CJD) is transmitted, suggest researchers from University College London.

10 Sep 2015

HUCBC-derived monocytes diminishes Aβ pathology, improves cognition in AD modeled mice

Alzheimer's disease (AD), which affects an estimated 26 million people worldwide, is the fourth leading cause of death among the elderly and the leading cause of dementia. Predictions are that the number of AD cases will quadruple by 2050.

9 Sep 2015

New UC Davis study suggests that popular molecular tests over-diagnose C. difficile infections

Clostridium difficile is a common cause of infection and diarrhea in hospitalized patients, but a new study by UC Davis pathologists suggests that many patients are mistakenly diagnosed and do not need antibiotic treatment. As a result, patients are likely being over-diagnosed and over-treated, adding to concerns about antibiotic resistance, damage to the "good" bacteria that live in people's intestines, and increased health-care costs.

9 Sep 2015

CSUSM gains initial accreditation for Master of Science in Speech-Language Pathology program

California State University San Marcos has earned initial accreditation from the Council on Academic Accreditation (CAA) of the American Speech-Language Hearing Association for the Master of Science in Speech-Language Pathology (SLP) program.

9 Sep 2015

Penns' Abramson Cancer Center rated as 'exceptional' by NCI

The University of Pennsylvania's Abramson Cancer Center (ACC) has received an "exceptional" rating by the National Cancer Institute during an extensive peer-review process for its five-year competitive research support grant. The rating is the highest possible for an NCI cancer center.

9 Sep 2015

UCSF researchers lead $10 million research project on pediatric cancer

Researchers at UC San Francisco are leading a five-year, $10 million research project dedicated to pediatric cancer, funded by the first grant of its kind to focus on a molecular pathway that underlies many cancers rather than on a cancer in a particular organ or tissue in the body.

9 Sep 2015

Pathology News and Research

Further Reading

Johns Hopkins scientists discover earliest premalignant genetic changes that mark potential onset of lung cancer

UF researchers create fungi database to promote healthier environments

Salsalate drug offers new hope for treating Alzheimer's disease and FTD

Hypertension drugs block proteins that cause inflammation after traumatic brain injury

New study reshapes how scientists look at dengue virus

Genetically engineered vaccine eradicates precancerous cervical lesions

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

UCI agrees to use MAggPI's web-based digital whole slide imaging to teach medical students

Using integrated molecular pathology to manage incidental pancreatic cysts: an interview with Dr Ananya Das

Study reveals how leukemia cells evade deadly effects of BRD4 inhibitors

Three-drug strategy effective against drug-resistant staph infection, finds new research

Two St. Louis institutions collaborate to create Center for Clinical Pharmacology

Penn Medicine researchers show that DNA editing errors can lead to cancer

Chronic alcohol consumption disrupts liver molecular circadian clock, leads to alcoholic liver disease

Signs of Alzheimer’s found in growth hormone patients

HUCBC-derived monocytes diminishes Aβ pathology, improves cognition in AD modeled mice

New UC Davis study suggests that popular molecular tests over-diagnose C. difficile infections

CSUSM gains initial accreditation for Master of Science in Speech-Language Pathology program

Penns' Abramson Cancer Center rated as 'exceptional' by NCI

UCSF researchers lead $10 million research project on pediatric cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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