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Navigating the challenges and progress in dengue vaccine development

Dengue fever caused by a flavivirus named DENV is a major global health challenge, risking almost half of the world's population. Since the early 20th century, the scientific community has faced multiple challenges to develop effective dengue vaccines.

30 May 2025

New antibody discovery reveals powerful immune defense against tuberculosis

Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ability to fight Mycobacterium tuberculosis (Mtb), the bacteria responsible for tuberculosis (TB).

30 May 2025

WHO releases first-ever position paper on immunization products to protect infants against RSV

Today, the World Health Organization (WHO) published its first-ever position paper on immunization products to protect infants against respiratory syncytial virus (RSV) – the leading cause of acute lower respiratory infections in children globally.

30 May 2025

New electrochemical device advances point-of-care HIV diagnostics

Accurate monitoring of CD4+ T cell counts is vital for evaluating immune health and guiding treatment in people living with Human Immunodeficiency Virus (HIV).

30 May 2025

Early allergen introduction reduces childhood food allergy risk

Investigating allergy prevention, this research highlights early intervention strategies and the promise of biologic treatments in managing allergic conditions.

29 May 2025

Early measles vaccination gains urgency amid global outbreak

The global measles outbreak must trigger an urgent debate into whether a vaccine should be recommended earlier to better protect against the highly contagious disease during infancy, a new review states.

29 May 2025

New material could improve delivery and effectiveness of mRNA vaccines

A new material developed at Cornell University could significantly improve the delivery and effectiveness of mRNA vaccines by replacing a commonly used ingredient that may trigger unwanted immune responses in some people.

29 May 2025

Prior COVID-19 vaccination provides strong protection against emerging variants

Prior COVID-19 vaccination did not stop the immune system from mounting a protective response to the Delta and Omicron strains, though new mutation-specific antibody production dipped slightly, according to a study led by researchers at the University of Arizona Health Sciences and published in Nature Immunology.

27 May 2025

A collaborative initiative by ISSCR toward responsible adoption of stem cell models

Advances in human stem cell-derived disease models have the potential to augment our predictive power for the efficacy and safety of new drugs.

27 May 2025

Scientists make major progress toward an effective HIV vaccine

In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a wide range of HIV strains-including those that are typically the hardest to stop.

27 May 2025

Federal cuts ripple through a bioscience hub in rural Montana

Scientists are often careful to take off their work badges when they leave the campus of one of the nation's top research facilities, here in southwestern Montana's Bitterroot Valley.

27 May 2025

Tufts researchers develop dental floss sensor for real time stress monitoring

Chronic stress can lead to increased blood pressure and cardiovascular disease, decreased immune function, depression, and anxiety.

23 May 2025

New technique rapidly tracks cell state changes through density measurements

Measuring the density of a cell can reveal a great deal about the cell's state. As cells proliferate, differentiate, or undergo cell death, they may gain or lose water and other molecules, which is revealed by changes in density.

21 May 2025

Blocking IL1RAP protein may offer new approach to treat atherosclerosis

Atherosclerosis is the buildup of fat and calcium in the walls of blood vessels and represents the most common cause of cardiovascular disease.

21 May 2025

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

Headway in Alzheimer’s disease care: New guidance provides recommendations for use of anti-amyloid monoclonal antibodies

The new guidelines for the use of monoclonal antibodies (mAbs) published in Neurodegenerative Diseases, serve as exemplary clinical recommendations for clinicians and healthcare providers, supporting the advancement of Alzheimer's disease treatment in Switzerland.

From S. Karger AG 19 May 2025

What makes H5N1 a pandemic risk and how can we stop it?

A new PEARLS article in PLoS Pathogens reviews the rapid evolution and pandemic potential of emerging influenza A viruses, with a focus on H5N1. It highlights scientific advances and future strategies to outpace the virus, from next-generation vaccines to AI-driven antiviral discovery.

19 May 2025

USPSTF urges universal syphilis screening in pregnancy to prevent congenital infections

The US Preventive Services Task Force (USPSTF) reaffirms its recommendation for universal syphilis screening in pregnancy, citing strong evidence for early detection and prevention of congenital syphilis. Despite ongoing disparities and rising rates, early screening and treatment remain essential to improving outcomes for mothers and infants.

18 May 2025