Immune Response News and Research

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Targeting the tumor microenvironment to improve osteosarcoma outcomes

The complex tumor microenvironment (TME) in osteosarcoma is emerging as a critical factor in disease progression and treatment resistance.

26 Jun 2025

Gut microbe emerges as a promising tool in the fight against COVID-19

Researchers found that Akkermansia muciniphila boosts lung-specific antiviral immunity against SARS-CoV-2 in mice by modulating the gut–lung axis. This commensal gut bacterium shows promise as a potential biomarker and biotherapeutic candidate for COVID-19 and other respiratory infections.

25 Jun 2025

New insights into the role of diet and microbiome in gastric cancer

Gastric cancer (GC), once primarily seen in older adults, is on the rise among younger individuals in developed countries.

25 Jun 2025

Aging and extreme heat combine to raise risk of deadly infections

As we age, extreme heat causes many heat-related illnesses that can lead to serious health issues. A new study from the University of California, Irvine's Joe C. Wen School of Population & Public Health adds to that list.

25 Jun 2025

Fructose consumption increases immune cell sensitivity to bacterial toxins

Despite medical advances, infectious diseases caused by bacteria and viruses are still among the most common causes of death worldwide.

24 Jun 2025

New PET radiotracer offers clearer view of brain inflammation

A newly developed PET radiotracer has shown the ability to produce high-quality images of real-time brain inflammation, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

24 Jun 2025

Many older people embrace vaccines. Research is proving them right.

Kim Beckham, an insurance agent in Victoria, Texas, had seen friends suffer so badly from shingles that she wanted to receive the first approved shingles vaccine as soon as it became available, even if she had to pay for it out-of-pocket.

23 Jun 2025

Cord blood proteins help detect early sepsis in preterm infants

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and colleagues identified several proteins from the umbilical cord blood of preterm newborns that signal acute systemic inflammation as an immune response to infection, providing objective and noninvasive means to diagnose early onset sepsis.

20 Jun 2025

Immune changes predict heart risks in cancer patients on checkpoint inhibitors

New research has uncovered immune changes in cancer patients that could help identify which patients are most at risk of dangerous heart complications from cancer drugs, known as immune checkpoint inhibitors.

20 Jun 2025

Circular RNAs emerge as key players in hepatitis B-related liver cancer

Hepatitis B virus-induced hepatocellular carcinoma (HCC) remains a major global health burden, and new therapeutic and diagnostic approaches are urgently needed.

20 Jun 2025

Autoantibodies against vinculin linked to childhood kidney disease

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein crucial for kidney cell structure—as a significant factor in INS.

19 Jun 2025

Researchers identify key differences in Alzheimer's progression in humans and animal models

Although it is known that Alzheimer's disease can start up to 20 years before the first symptoms appear, the lack of knowledge about how it progresses prevents the development of effective treatments, as well as a clear diagnosis to confront this neurodegenerative disease, which origin is also unknown.

19 Jun 2025

Scientists find hundreds of genes that behave like light switches

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer light.

19 Jun 2025

New dual-adjuvant vaccine strategy offers hope in the fight against HIV

In the quest to develop an effective HIV vaccine, scientists from Scripps Research have made a significant leap forward. They found that a two-part delivery strategy can train the immune system to produce a stronger response to HIV, offering new hope in the fight against one of the world's most elusive viruses.

19 Jun 2025