Major Depressive Disorder News and Research

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Major Depressive Disorder (MDD) is a psychiatric condition characterized by depressed mood or anhedonia (significant loss of interest or pleasure). The condition affects more than 15.7 million adults and approximately 3 million adolescents (aged 13 to 17 years) in the USA each year.

DSM-IV insufficient for bipolar disorder diagnosis

Research findings support concerns that the text revision of the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders is too restrictive for diagnosing bipolar disorder.

11 Oct 2013

Alkermes' ALKS 5461 drug gets FDA Fast Track status for major depressive disorder

Alkermes plc today announced that the U.S. Food and Drug Administration has granted Fast Track status for ALKS 5461 for the adjunctive treatment of major depressive disorder in patients with an inadequate response to standard therapies.

10 Oct 2013

Alkermes announces plans to advance ALKS 5461 phase 3 program for major depressive disorder

Alkermes plc today announced that it has successfully completed its End-of-Phase 2 interactions with the U.S. Food and Drug Administration (FDA), and the company plans to advance ALKS 5461 into phase 3 development in early 2014.

9 Oct 2013

Bipolar disorder ‘distinct’ from borderline personality disorder

Researchers say that there are clear clinical differences between depressed patients with bipolar II disorder and those with borderline personality disorder, which supports the two being treated as distinct conditions.

8 Oct 2013

Brain & Behavior Research Foundation to hold research symposium on mental health

The Brain & Behavior Research Foundation, an organization dedicated to improving the lives of those with mental illness through the transformative power of neuroscience and psychiatric research, will hold its 25th Annual Mental Health Research Symposium on Friday, October 25th from 9:00 am to 4:30 p.m. at the Kaufman Music Center, located at 129 W. 67th St. in New York City.

8 Oct 2013

PMDD may shed light on complex interactions between sex hormones and mood

Improved understanding of the role of female sex hormones on the drivers and symptoms of premenstrual dysphoric disorder (PMDD) may shed light on the complex interactions between sex hormones and mood, potentially helping to explain the increased prevalence of mood disorders in women.

8 Oct 2013

FDA Approves Takeda-Lundbeck Drug For Major Depressive Disorder

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1 Oct 2013

Emotion regulation training enhances efficacy of inpatient cognitive behavioral therapy for MDD

A new psychotherapeutic ingredient, emotion regulation skills training, has been found to enhance standard cognitive behavior therapy for depression in a trial published in the current issue of Psychotherapy and Psychosomatics.

1 Oct 2013

FDA approves Brintellix drug to treat depressive disorder in adults

The U.S. Food and Drug Administration today approved Brintellix (vortioxetine) to treat adults with major depressive disorder.

1 Oct 2013

Study reveals new findings on role of psychotherapy in regulating serotonin receptors

A paper published in the current issue of Psychotherapy and Psychosomatics provides new findings on the role of psychotherapy in regulating serotonin receptors.

30 Sep 2013

Study: Countries with lower gun ownership are safer than those with higher gun ownership

A new study reports that countries with lower gun ownership are safer than those with higher gun ownership, debunking the widely quoted hypothesis that guns make a nation safer.

19 Sep 2013

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Results of a Pfizer-commissioned study published this month in Annals of Internal Medicine reveal that smokers with a past or present diagnosis of major depressive disorder (MDD)* taking varenicline had a significantly higher likelihood of quitting smoking (after 12 weeks and at 52 weeks) than those who were given a placebo.

18 Sep 2013

Varenicline drug helps people with depression quit smoking, say researchers

About half of smokers seeking treatment for smoking cessation have a history of depression. Compared with smokers who are not depressed, those who suffer from a major depressive disorder have greater difficulty quitting.

17 Sep 2013

Improved pediatric bipolar screen unveiled

Researchers have developed a screening instrument for detecting bipolar disorder in children and adolescents from the general population.

30 Aug 2013

Heritability of severe mental illness may be underestimated

Around one in three children of parents with a severe mental illness – schizophrenia, bipolar disorder, or major depressive disorder – will develop such a disorder themselves by early adulthood, a meta-analysis has found.

29 Aug 2013

Personality may be key to genetics of bipolar disorder

People with bipolar disorder vary significantly from their unaffected relatives, and from healthy controls, on several measures of personality, a study shows.

28 Aug 2013

Identifying bipolarity through MRI's proves successful in initial results

What are some of the most troubling numbers in mental health? Six to 10 -- the number of years it can take to properly diagnose a mental health condition. Dr. Elizabeth Osuch, a Researcher at Lawson Health Research Institute and a Psychiatrist at London Health Sciences Centre and the Department of Psychiatry at Western University, is helping to end misdiagnosis by looking for a 'biomarker' in the brain that will help diagnose and treat two commonly misdiagnosed disorders.

16 Aug 2013

Few physicians receive adequate training to help patients with chronic pain

Pain is the most common reason a patient sees a physician but few physicians have received adequate training to help their patients, according to a Henry Ford Hospital article published in the Journal of American Osteopathic Association.

13 Aug 2013

Study: Mental health services should be included into disaster response plans

Mental health services should be integrated into disaster response as part of emergency services planning, according to a new study by UT Southwestern Medical Center psychiatrists who completed an exhaustive review of articles on the aftereffects of disasters on mental health.

8 Aug 2013

Targacept reports net loss of $12.4 million for Q2 2013

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today reported its financial results for the second quarter and six months ended June 30, 2013.

6 Aug 2013

Major Depressive Disorder News and Research

Further Reading

DSM-IV insufficient for bipolar disorder diagnosis

Alkermes' ALKS 5461 drug gets FDA Fast Track status for major depressive disorder

Alkermes announces plans to advance ALKS 5461 phase 3 program for major depressive disorder

Bipolar disorder ‘distinct’ from borderline personality disorder

Brain & Behavior Research Foundation to hold research symposium on mental health

PMDD may shed light on complex interactions between sex hormones and mood

FDA Approves Takeda-Lundbeck Drug For Major Depressive Disorder

Emotion regulation training enhances efficacy of inpatient cognitive behavioral therapy for MDD

FDA approves Brintellix drug to treat depressive disorder in adults

Study reveals new findings on role of psychotherapy in regulating serotonin receptors

Study: Countries with lower gun ownership are safer than those with higher gun ownership

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Varenicline drug helps people with depression quit smoking, say researchers

Improved pediatric bipolar screen unveiled

Heritability of severe mental illness may be underestimated

Personality may be key to genetics of bipolar disorder

Identifying bipolarity through MRI's proves successful in initial results

Few physicians receive adequate training to help patients with chronic pain

Study: Mental health services should be included into disaster response plans

Targacept reports net loss of $12.4 million for Q2 2013

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