Polymerase News and Research

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Study uncovers pathogenic variants in the chromatin modifier EZH1 as the cause of neurodevelopmental disorders

Study identified pathogenic variants in the EZH1 as a cause of neurodevelopmental disorders.

14 Jul 2023

pAQ monitor: innovative device provides real-time surveillance of SARS-CoV-2 aerosols

Researchers presented the proof-of-concept of a pathogen Air Quality (pAQ) monitor.

13 Jul 2023

IL-9 identified as contributor to viral spread and airway inflammation in COVID-19

Researchers used a K18-hACE2 transgenic (ACE2.Tg) mouse model to demonstrate that interleukin-9 (IL-9).

13 Jul 2023

How does SARS-CoV-2 affect the placenta during pregnancy?

Researchers examine host responses to SARS-CoV-2 within the placenta using transcriptomics.

12 Jul 2023

Lollipop-based saliva collection system shows promise for more enjoyable, accurate diagnostic testing

A lollipop might be a sweet reward for a kid who's endured a trip to the doctor's office, but now, this candy could make diagnostic testing during a visit less invasive and more enjoyable.

10 Jul 2023

Real-time monitor can detect SARS-CoV-2 in indoor air within 5 minutes

Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses.

10 Jul 2023

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

Researchers investigated the role of senescent cells in the context of SARS-CoV-2 infection.

10 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

The vital role of smartphone apps during the COVID-19 pandemic

At the start of the coronavirus disease 2019 (COVID-19) pandemic, analog techniques like nasopharyngeal swab specimens for polymerase chain reaction (PCR) testing were prominent. The widespread use of nonpharmaceutical interventions (NPIs) such as facemasks and social distancing was reminiscent of the influenza outbreak in 1918.

9 Jul 2023

Dengue outbreak overlapped COVID-19 crisis in Key Largo, Florida in 2020: Call for enhanced disease testing protocols

Detection and response to a dengue outbreak in Florida during the COVID-19 pandemic in 2020, highlighting the challenges of diagnosing febrile illnesses and the need for surveillance. This study examines the impact and management of dengue cases in the context of the ongoing pandemic.

5 Jul 2023

Moderna COVID-19 vaccine effective in children five and under

mRNA-1273 vaccine (Moderna) shows strong effectiveness in reducing symptomatic SARS-CoV-2 infection and COVID-19-related hospitalization in children aged 6 months to 5 years. Further research is needed to explore long-term effectiveness and the potential need for booster doses.

5 Jul 2023

A novel RSV vaccine that could be effective across all ages

Researchers evaluate the in vivo efficacy of a respiratory syncytial virus vaccine in old and young rats.

4 Jul 2023

New regulatory system discovered in malaria parasite

Gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is regulated by melatonin (the circadian signaling hormone) in host blood, and intrinsic parasite cues, via a factor called ApSigma, as identified by a recent study aided by Tokyo Tech's World Research Hub Initiative.

3 Jul 2023

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

3 Jul 2023

Stalled progress: Enteric infection reduction efforts slowed in 2022 despite pandemic easing

The research paper focuses on the lack of progress in reducing enteric infection incidence in 2022 despite the subsiding influence of the COVID-19 pandemic. It emphasizes the need for collaborative efforts among food stakeholders and regulators to mitigate pathogen contamination during poultry slaughter and prevent contamination of leafy greens.

3 Jul 2023

Wastewater surveillance highlights significant underestimation of COVID-19 cases in Canada

Research examines the correlation between SARS-CoV-2 levels in untreated water and COVID-19 cases and hospitalizations in Ontario, Canada. It also highlights the value of wastewater data in enhancing local decision-making and COVID-19 surveillance systems.

3 Jul 2023

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Researchers used antibody testing to predict the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

3 Jul 2023

Polymerase News and Research

Study uncovers pathogenic variants in the chromatin modifier EZH1 as the cause of neurodevelopmental disorders

pAQ monitor: innovative device provides real-time surveillance of SARS-CoV-2 aerosols

IL-9 identified as contributor to viral spread and airway inflammation in COVID-19

How does SARS-CoV-2 affect the placenta during pregnancy?

Lollipop-based saliva collection system shows promise for more enjoyable, accurate diagnostic testing

Real-time monitor can detect SARS-CoV-2 in indoor air within 5 minutes

The causative role of age-associated pre-existing senescent cells on COVID-19 severity

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

The vital role of smartphone apps during the COVID-19 pandemic

Dengue outbreak overlapped COVID-19 crisis in Key Largo, Florida in 2020: Call for enhanced disease testing protocols

Moderna COVID-19 vaccine effective in children five and under

A novel RSV vaccine that could be effective across all ages

New regulatory system discovered in malaria parasite

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Stalled progress: Enteric infection reduction efforts slowed in 2022 despite pandemic easing

Wastewater surveillance highlights significant underestimation of COVID-19 cases in Canada

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Insights gained from genetically modified pig heart transplantation

Advances in influenza research

Understanding the biological effects of SARS-CoV-2 persistence in children

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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