Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Ligand's total revenues increase 37% to $16.0 million in first quarter 2014

Ligand Pharmaceuticals Incorporated today reported financial results for the three months ended March 31, 2014, and provided an operating forecast and program updates.

7 May 2014

Targacept reports net loss of $11.6M in first quarter 2014

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics™, today reported its financial results for the first quarter ended March 31, 2014.

7 May 2014

Young blood can rejuvenate brains of old mice

Something - or some things - in the blood of young mice has the ability to restore mental capabilities in old mice, a new study by Stanford University School of Medicine investigators has found.

6 May 2014

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

Cajal-Retzius cells are reelin-secreting neurons in the marginal zone of the neocortex and hippocampus.

6 May 2014

BrightFocus Foundation honors 5 outstanding scientists in fields of macular degeneration, glaucoma

The BrightFocus Foundation today honored five outstanding scientists in the fields of macular degeneration and glaucoma, presenting them with named research awards at an event during the annual meeting of the Association for Research in Vision and Ophthalmology.

6 May 2014

Calgary researcher receives $130,000 grant to develop clinical decision tools to aid epilepsy research

A researcher from the University of Calgary is receiving $130,000 to develop clinical decision tools to aid a physician's understanding of how a patient will respond to different treatments.

6 May 2014

Novogen partners with Genea Biocells to accelerate testing for neurodegenerative diseases

Novogen Limited, an oncology drug development company, today announced a collaboration with Australian company, Genea Biocells, to accelerate testing of their super-benzopyran (SBP) drugs for degenerative diseases of the nervous system and muscles.

5 May 2014

Researchers discover potential genetic variant that may make brains more resilient against Alzheimer's

Autopsies have revealed that some individuals develop the cellular changes indicative of Alzheimer's disease without ever showing clinical symptoms in their lifetime.

5 May 2014

Mayo Clinic neuroscientists define subtype of Alzheimer's disease

Neuroscientists at Mayo Clinic in Florida have defined a subtype of Alzheimer's disease (AD) that they say is neither well recognized nor treated appropriately.

2 May 2014

Study examines potential benefits of low fat diet on management of MS

People with multiple sclerosis who for one year followed a plant-based diet very low in saturated fat had much less MS-related fatigue at the end of that year - and significantly less fatigue than a control group of people with MS who didn't follow the diet, according to an Oregon Health & Science University study being presented today at the American Academy of Neurology's annual meeting in Philadelphia, Pa.

2 May 2014

Researchers find two types of neurons that enable spinal cord to control skilled forelimb movement

Researchers have identified two types of neurons that enable the spinal cord to control skilled forelimb movement. The first is a group of excitatory interneurons that are needed to make accurate and precise movements; the second is a group of inhibitory interneurons necessary for achieving smooth movement of the limbs.

2 May 2014

Scientists receive $2.3M grant to develop new technology to diagnose cancer, rheumatoid arthritis and colitis

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded a $2.3 million grant from the National Institute of General Medical Sciences of the National Institutes of Health to develop new technology to diagnose cancer, rheumatoid arthritis and colitis.

2 May 2014

Study finds that Medicare patients with dementia more likely to be readmitted within 30 days

A review of more than 25,000 admissions of Medicare beneficiaries to Rhode Island hospitals has found that patients with a documented diagnosis of dementia are nearly 20 percent more likely to be readmitted within 30 days than those without dementia.

30 Apr 2014

GE Healthcare announces commercial availability of new Alzheimer’s diagnostic tool

GE Healthcare today announced the first seven markets where Vizamyl (Flutemetamol F18 injection), a radioactive diagnostic agent approved by the FDA will be available. Late in the second quarter of 2014, Vizamyl will be available to imaging centers near East Rutherford, NJ, Woburn, MA, Beltsville, MD, East Lansing, MI, Dallas, TX, Phoenix, AZ and Colton, CA.

29 Apr 2014

AAN review finds certain forms of medical marijuana can help treat some symptoms of MS

A review by the American Academy of Neurology of available scientific research on the use of medical marijuana in brain diseases finds certain forms of medical marijuana can help treat some symptoms of multiple sclerosis (MS), but do not appear to be helpful in treating drug-induced (levodopa) movements in Parkinson's disease.

29 Apr 2014

Severe diabetes linked to brain atrophy

Type 2 diabetes may be associated with brain degeneration, according to a new multicenter study published online in the journal Radiology. The study also found that, contrary to common clinical belief, diabetes may not be directly associated with small vessel ischemic disease, where the brain does not receive enough oxygenated blood.

29 Apr 2014

Strategy-based cognitive training has potential to enhance cognitive performance

Strategy-based cognitive training has the potential to enhance cognitive performance and spill over to real-life benefit according to a data-driven perspective article by the Center for BrainHealth at The University of Texas at Dallas published in the open-access journal Frontiers in Systems Neuroscience.

29 Apr 2014

Understanding biological underpinnings of source-memory impairment in humans

Indiana University neuroscientists Jonathon Crystal and Wesley Alford are zeroing in with increasing certainty on the notion that nonhuman animals have a particular type of memory known as "source memory," long seen as exclusively human.

26 Apr 2014

Study shows mild cognitive impairment linked to early death

Mayo Clinic research studying the relationship between death and the two types of mild cognitive impairment (MCI) suggests that people who have these conditions die at a higher rate than people without MCI.

25 Apr 2014

Researchers develop gene therapy reversing memory loss in mice with early-stage Alzheimer's

Alzheimer's disease is the first cause of dementia and affects some 400,000 people in Spain alone. However, no effective cure has yet been found. One of the reasons for this is the lack of knowledge on the cellular mechanisms which cause alterations in nerve transmissions and the loss of memory in the initial stages of the disease.

25 Apr 2014

Alzheimer's Disease News and Research

Further Reading

Ligand's total revenues increase 37% to $16.0 million in first quarter 2014

Targacept reports net loss of $11.6M in first quarter 2014

Young blood can rejuvenate brains of old mice

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

BrightFocus Foundation honors 5 outstanding scientists in fields of macular degeneration, glaucoma

Calgary researcher receives $130,000 grant to develop clinical decision tools to aid epilepsy research

Novogen partners with Genea Biocells to accelerate testing for neurodegenerative diseases

Researchers discover potential genetic variant that may make brains more resilient against Alzheimer's

Mayo Clinic neuroscientists define subtype of Alzheimer's disease

Study examines potential benefits of low fat diet on management of MS

Researchers find two types of neurons that enable spinal cord to control skilled forelimb movement

Scientists receive $2.3M grant to develop new technology to diagnose cancer, rheumatoid arthritis and colitis

Study finds that Medicare patients with dementia more likely to be readmitted within 30 days

GE Healthcare announces commercial availability of new Alzheimer’s diagnostic tool

AAN review finds certain forms of medical marijuana can help treat some symptoms of MS

Severe diabetes linked to brain atrophy

Strategy-based cognitive training has potential to enhance cognitive performance

Understanding biological underpinnings of source-memory impairment in humans

Study shows mild cognitive impairment linked to early death

Researchers develop gene therapy reversing memory loss in mice with early-stage Alzheimer's

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