Immune System News and Research

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Lab study of South African SARS-CoV-2 variant and Moderna vaccine: reduced neutralization, but still protective

Researchers from the US recently compared antibody binding and viral neutralization against 2 SARS-CoV-2 variants that emerged in different parts of the world. The researchers used sera from spike mRNA vaccinated and naturally infected individuals against a circulating B.1 variant and the emerging B.1.351 variant. The study is published on the preprint server bioRxiv.

24 Feb 2021

CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma

In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found.

24 Feb 2021

Tumors use unique mechanism to switch on regulatory T cells for protection

Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system.

24 Feb 2021

SARS-CoV-2 does not infect the entire body in the same way, finds study

COVID-19, the disease caused by the pandemic coronavirus SARS-CoV-2, is primarily regarded as a respiratory infection. Yet the virus has also become known for affecting other parts of the body in ways not as well understood, sometimes with longer-term consequences, such as heart arrhythmia, fatigue and "brain fog."

24 Feb 2021

AI-based 3D holographic microscopy found to be better at analyzing cancer immunotherapy

Live tracking and analyzing of the dynamics of chimeric antigen receptor (CAR) T-cells targeting cancer cells can open new avenues for the development of cancer immunotherapy.

24 Feb 2021

GW team to play a role in Sanofi COVID-19 vaccine clinical trial

The George Washington University announced today its participation in a Sanofi COVID-19 vaccine clinical trial. GW was selected as one of approximately 25 sites in the United States to launch a phase 2 study for its adjuvanted recombinant protein-based COVID-19 vaccine candidate.

24 Feb 2021

In Vivo Probes for Detecting Inflammation Markers in Humans and Animals

News-Medical talks to Parry Hashemi about research on in vivo probes for detecting inflammation markers in humans and animals she will present at Pittcon.

From Pittcon 24 Feb 2021

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

New research by a team of scientists at Stanford University School of Medicine in the U.S. found that both the UK and South African SARS-CoV-2 variants display tighter binding to the ACE2 receptor.

24 Feb 2021

Researchers explore how N501Y mutation in SARS-CoV-2 increases viral transmissibility

Researchers at Erasmus University Medical Center in The Netherlands have explored how and why new variants of SARS-CoV-2 have exhibited heightened infectivity.

24 Feb 2021

Hyperactive immune system contributes to COVID-19 severity, lung damage

Researchers have pinpointed a helper T cell population in the lungs of patients with severe COVID-19 that may be central to the development of hyperinflammation, lung injury, and subsequent acute respiratory distress syndrome (ARDS) during disease.

24 Feb 2021

TBE patients continue to be affected by long-term problems

Impaired memory, reduced motivation, and declining motor skills. These are some of the problems that may persist several years after people contract tick-borne encephalitis, a University of Gothenburg thesis shows.

23 Feb 2021

Innate immune system overreacts in patients with severe COVID-19

In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots (thrombi) and deterioration in oxygen saturation that affect the patients.

23 Feb 2021

After billions of dollars and dozens of wartime declarations, why are vaccines still in short supply?

The U.S. government has invested billions of dollars in manufacturing, used a wartime act dozens of times to boost supplies and yet there's still not enough covid vaccine on the way to meet demand — or even the government's own goals for national immunization.

23 Feb 2021

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several types of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations.

23 Feb 2021

Protective COVID-19 antibodies can transfer from mothers to babies in the womb

Antibodies that guard against COVID-19 can transfer from mothers to babies while in the womb, according to a new study from Weill Cornell Medicine and NewYork-Presbyterian researchers published in the American Journal of Obstetrics and Gynecology.

23 Feb 2021

Universal strain of bacteria derived from healthy human skin can treat eczema

In a new study out of University of California San Diego School of Medicine, researchers have identified a universal strain of bacteria derived from healthy human skin that can treat the most common type of eczema, also known as atopic dermatitis.

23 Feb 2021

People with absence of natural killer cell receptor are likely to develop severe COVID-19

The course and severity of COVID-19 in individual patients are largely influenced by the interaction between the SARS-CoV-2 coronavirus and the human immune system.

23 Feb 2021

Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress

Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS).

22 Feb 2021

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Monoclonal antibodies are part of the therapeutic arsenal for eliminating cancer cells. Some make use of the immune system to act and belong to a class of treatment called "immunotherapies." But how do these antibodies function within the tumor? And how can we hope to improve their efficacy?

22 Feb 2021

Virus-specific cellular immunity may be essential for long-term protection against SARS-CoV-2

Researchers from China and the US recently synthesized select peptide pools of the structural and functional proteins of SARS-CoV-2, including spike (S), envelope (E), membrane (M), nucleocapsid (N), and protease (P) proteins as target antigens to assess COVID-19-specific immunity.

22 Feb 2021

Immune System News and Research

Lab study of South African SARS-CoV-2 variant and Moderna vaccine: reduced neutralization, but still protective

CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma

Tumors use unique mechanism to switch on regulatory T cells for protection

SARS-CoV-2 does not infect the entire body in the same way, finds study

AI-based 3D holographic microscopy found to be better at analyzing cancer immunotherapy

GW team to play a role in Sanofi COVID-19 vaccine clinical trial

In Vivo Probes for Detecting Inflammation Markers in Humans and Animals

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

Researchers explore how N501Y mutation in SARS-CoV-2 increases viral transmissibility

Hyperactive immune system contributes to COVID-19 severity, lung damage

TBE patients continue to be affected by long-term problems

Innate immune system overreacts in patients with severe COVID-19

After billions of dollars and dozens of wartime declarations, why are vaccines still in short supply?

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

Protective COVID-19 antibodies can transfer from mothers to babies in the womb

Universal strain of bacteria derived from healthy human skin can treat eczema

People with absence of natural killer cell receptor are likely to develop severe COVID-19

Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Virus-specific cellular immunity may be essential for long-term protection against SARS-CoV-2

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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