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Diagnostic assays that use the 2019-nCoV-N1 primer-probe are unlikely to be impacted by Omicron variant

A new study aimed to detect the genomic material of SARS-CoV-2 and its variants, such as the recently emerged variant of concern (VOC) Omicron.

21 Dec 2021

Stabilizing the long-term endemic behavior of COVID-19

Researchers used a classic age and contact structured model to explore the several reopening and vaccination coverage scenarios regarding the COVID-19 pandemic.

21 Dec 2021

Efficacy of the mRNA-1273 vaccine against emerging COVID-19 variants

A new study emphasized the effectiveness of two doses of mRNA-1273 in preventing infection with SARS-CoV-2 and hospital admission with covid-19 due to variants including delta.

21 Dec 2021

Estimating vaccine efficacy against COVID-like illness from omicron and other COVID-19 variants

A new study combines real-time syndromic surveillance data from daily cross-sectional surveys with a COVID-like illness (CLI) prevalence-based vaccine efficacy estimator to better explain the early onset of the omicron variant.

21 Dec 2021

$Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma$

Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma

Early results from an Alliance for Clinical Trials in Oncology randomized clinical trial of adults with multiple myeloma relapsing on frontline lenalidomide therapy showed that adding ixazomib (Ninlaro®) to pomalidomide and dexamethasone as part of second line therapy extended the length of time patients lived before their disease worsened (progression-free survival) compared with patients who received pomalidomide and dexamethasone.

21 Dec 2021

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

In a new study, published on the bioRxiv* preprint server, scientists showed in a mice model that three doses of the same synthetic peptide vaccine, eliciting an exclusive CD8+ T cell response against one SARS-CoV-2 Spike epitope, protected against lethal SARS-CoV-2 infection, in the absence of neutralizing antibodies. Researchers also showed that the third dose resulted in superior generation of effector-memory T cells in the circulation and tissue-resident memory T (TRM) cells.

20 Dec 2021

An Omicron wave predicted for England from December 2021 to April 2022

A study, published on the medRxiv* preprint server, focuses on the interaction between Omicron variants and public health interventions in England that promote immunity.

20 Dec 2021

New oral pill for COVID-19 home treatment

As cases and hospitalizations continue to rise in many countries, new treatments are being sought to arrest the progression of the disease, preventing severe illness and death or disability. One such is the small molecule molnupiravir, the focus of a new research paper.

20 Dec 2021

New study suggests most monoclonal antibody treatments are ineffective against Omicron SARS-CoV-2 variant

The arrival of the Omicron (B.1.1.529) variant has brought into question the effectiveness of current COVID-19 treatments in preventing infection and death. New research published in the preprint bioRxiv* server suggests the efficacy of most monoclonal antibody treatments are ineffective against Omicron.

20 Dec 2021

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Researchers discuss the likely impact on current convalescent therapies and immunity of vaccinated individuals against the SARS-CoV-2 Omicron variant.

20 Dec 2021

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Researchers discuss the sensitivity of the SARS-CoV-2 Omicron variant towards various monoclonal antibodies.

20 Dec 2021

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

A new study expands the understanding of the impact of receiving a prophylactic monoclonal antibody infusion, as well as other variables, on the endogenous immune response to complete COVID-19 immunization.

20 Dec 2021

Study offers an analysis of fungicide resistance and informs management strategies

The use of fungicides to treat plant pathogens dates back 150 years, when a mixture of lime and copper sulfate, known as the "Bordeaux mixture," was used to control fungal diseases in French vineyards. However, as fungicide usage has increased, their efficacy has decreased thanks to a phenomenon known as fungicide resistance.

19 Dec 2021

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

A new study evaluates the repRNA vaccine expressing the SARS-CoV-2 spike protein for the B.1.1.7 and B.1.351 variants in mice and hamsters.

19 Dec 2021

Echinacea purpurea may help prevent respiratory tract infections during COVID-19 pandemic

A new study describes the results of using an extract of the medicinal plant Echinacea purpurea to treat non-severe cases of COVID-19.

19 Dec 2021

Study examines the effects of methylphenidate on mental fatigue in multiple sclerosis patients

A team of researchers at Kessler Foundation studied the effects of methylphenidate on mental fatigue in individuals with multiple sclerosis (MS). This is the first study to examine the psychostimulant's effects on 'state' vs 'trait' mental fatigue in MS.

18 Dec 2021

Efficacy News and Research

Diagnostic assays that use the 2019-nCoV-N1 primer-probe are unlikely to be impacted by Omicron variant

Stabilizing the long-term endemic behavior of COVID-19

Efficacy of the mRNA-1273 vaccine against emerging COVID-19 variants

Estimating vaccine efficacy against COVID-like illness from omicron and other COVID-19 variants

Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma

Booster shots improve CD8+ T cell response to SARS-CoV-2 in animal model

An Omicron wave predicted for England from December 2021 to April 2022

New oral pill for COVID-19 home treatment

New study suggests most monoclonal antibody treatments are ineffective against Omicron SARS-CoV-2 variant

Omicron variant of SARS-CoV-2 exhibits striking antibody evasion

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Anti-SARS-CoV-2 antibody infusion shown to demonstrate robust immune response following COVID-19 vaccination

Study offers an analysis of fungicide resistance and informs management strategies

Efficacy of SARS-CoV2 variant-specific replicating RNA vaccines on SARS-CoV-2 variants of concern

Echinacea purpurea may help prevent respiratory tract infections during COVID-19 pandemic

Study examines the effects of methylphenidate on mental fatigue in multiple sclerosis patients

Scientists develop new immunotherapy for cancer based on transplant rejection mechanism

Efficacy of NVX-CoV2373 in the US and Mexican adult population

Modeling the potential interaction between COVID-19 outbreaks in susceptible and vaccinated sub-populations

Effectiveness of COVID-19 vaccines among older male veterans

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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